Heat shock protein 105 is overexpressed in squamous cell carcinoma and extramammary Paget disease but not in basal cell carcinoma

British Journal of Dermatology

Volumn 155, Issue 3, 2006, Pages 582-585

  Muchemwa, F C ^a   Nakatsura, T ^b   Ihn, H ^a   Kageshita, T ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b NATIONAL CANCER CENTER HOSPITAL EAST   (Japan)

Author keywords

Basal cell carcinoma; Extramammary Paget disease; Heat shock protein 105; Squamous cell carcinoma

Indexed keywords

CANCER TESTIS ANTIGEN; CANCER VACCINE; COMPLEMENTARY DNA; DNA VACCINE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 105; RECOMBINANT DNA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CANCER IMMUNOLOGY; CONTROLLED STUDY; DNA LIBRARY; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOGENICITY; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PAGET SKIN DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEROLOGICAL ANALYSIS OF RECOMBINANT COMPLEMENTARY DNA EXPRESSION; SEROLOGY; SKIN METASTASIS; SQUAMOUS CELL CARCINOMA; VACCINATION; WESTERN BLOTTING;

AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CARCINOMA, BASAL CELL; CARCINOMA, SQUAMOUS CELL; FEMALE; HSP110 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PAGET DISEASE, EXTRAMAMMARY; PAGET'S DISEASE, EXTRAMAMMARY; SKIN NEOPLASMS;

EID: 33747082152     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2006.07362.x     Document Type: Article

References (18)

1. Hatayama T, Yasuda K, Nishiyama E. Characterization of high molecular mass heat shock proteins and 42°C-specific heat shock proteins of murine cells. Biochem Biophys Res Commun 1994; 204:357-65.
2. Morris SD. Heat shock proteins and the skin. Exp Dermatol 2001; 27:220-4.
3. Xue JH, Fukuyama H, Nonoguchi K et al. Induction of Apg-1, a member of the heat shock protein 110 family, following transient forebrain ischaemia in the rat brain. Biochem Biophys Res Commun 1998; 247:796-801.
4. Kumagai J, Fukuda J, Kodayama H et al. Germ specific heat shock protein 105 binds to p53 in a temperature-sensitive manner in rat testis. Eur J Biochem 2000; 267:3073-8.
5. Yasuda K, Nakai A, Hatayama T, Nagata K. Cloning and expression of murine high molecular mass heat shock proteins, HSP105. J Biol Chem 1995; 270:29718-23.
6. Hatayama T, Honda K, Yukioka M. HeLa cells synthesise a specific heat shock protein upon exposure to heat shock at 42°C but not at 45°C. Biochem Biophys Res Commun 1986; 137:957-63.
7. Miyazaki M, Nakatsura T, Yokomine K et al. DNA vaccination of HSP105 leads to tumour rejection of colorectal cancer and melanoma in mice through activation of both CD4+ cells and CD8+ T cells. Cancer Sci 2005; 96:695-705.
8. Kai M, Nakatsura T, Egami H et al. Heat shock protein 105 is over-expressed in a variety of human tumors. Oncol Rep 2003; 10:1777-82.
9. Berchuck A, Soisson AP, Clarke-Pearson DL et al. Immunohistochemical expression of CA 125 in endometrial adenocarcinoma: correlation of antigen expression with metastatic potential. Cancer Res 1989; 49:2091-5.
10. Jones RE, Austin C, Ackerman AB. Extramammary Paget's disease: a critical re-examination. Am J Dermatopathol 1979; 1:101-32.
11. Zollo JD, Zetouni NC. The Roswell Park Cancer Institute experience with extramammary Paget's disease. Br J Dermatol 2000; 142:59-65.
12. Hatayama T, Nishiyama E, Yasuda K. Cellular localization of high-molecular-mass heat shock protein in murine cells. Biochem Biophys Res Commun 1994; 200:1367-73.
13. Bayerl C, Dorfner B, Rzany E et al. Heat shock protein HSP27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groups. Eur J Dermatol 1999; 4:281-4.
14. Trautinger F, Kindas-Mugge I, Dekrout B et al. Expression of the 27-kDa heat shock protein in human epidermis and in epidermal neoplasms: an immunohistochemical study. Br J Dermatol 1995; 133:194-202.
15. Goodheart HP. Benign versus malignant: a mini atlas. Part 2: the nose, ears and neck. Dermatology Rounds 2002; 5:283-5.
16. Nakatsura T, Senju S, Yamada K et al. Gene cloning of immunogenic antigens over-expressed in pancreatic cancer. Biochem Biophys Res Commun 2001; 281:936-44.
17. Tamura Y, Peng P, Liu K et al. Immunotherapy of tumours with autologous tumour derived heat shock protein preparation. Science 1997; 278:117-20.
18. Bagatell R, Beliakoff J, David CL et al. Hsp90 inhibitors deplete key anti-apoptotic proteins in pediatric solid tumor cells and demonstrate synergistic anticancer activity with cisplatin. Int J Cancer 2005; 113:179-88.