Ketamine administration disturbs behavioural and distributed neural correlates of fear conditioning in the rat

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 30, Issue 7, 2006, Pages 1209-1218

  Pietersen, Charmaine Y ^a   Bosker, Fokko J ^a   Postema, Folkert ^a   Fokkema, Dirk S ^a   Korf, Jakob ^a   den Boer, Johan A ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Amygdala; Anterior cingulate; cFos; Fear conditioning; NMDA receptor

Indexed keywords

KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROTEIN C FOS;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR DISORDER; CINGULATE GYRUS; CONDITIONING; CONTROLLED STUDY; FEAR; IMMOBILIZATION; MENTAL STRESS; NONHUMAN; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING; THALAMUS MIDLINE NUCLEUS;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BRAIN MAPPING; CONDITIONING (PSYCHOLOGY); ELECTROSHOCK; EXCITATORY AMINO ACID ANTAGONISTS; FEAR; IMMUNOHISTOCHEMISTRY; KETAMINE; MALE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33747059806     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2006.02.019     Document Type: Article

References (45)

1. Campeau S., Miserendino M.J., and Davis M. Intra-amygdala infusion of the N-methyl-d-aspartate receptor antagonist AP5 blocks acquisition but not expression of fear-potentiated startle to an auditory conditioned stimulus. Behav Neurosci 106 (1992) 569-574
2. Cardinal R.N., Parkinson J.A., Hall J., and Everitt B.J. Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex. Neurosci Biobehav Rev 26 (2002) 321-352
3. Chaouloff F. Serotonin, stress and corticoids. J Psychopharmacol 14 (2000) 139-151
4. Coyle J.T., and Tsai G. The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia. Psychopharmacology (Berl) 174 (2004) 32-38
5. Daniels W.M., Pietersen C.Y., Carstens M.E., and Stein D.J. Maternal separation in rats leads to anxiety-like behavior and a blunted ACTH response and altered neurotransmitter levels in response to a subsequent stressor. Metab Brain Dis 19 (2004) 3-14
6. Davidson R.J., and Irwin W. The functional neuroanatomy of emotion and affective style. Trends Cogn Sci 3 (1999) 11-21
7. Davis M., Rainnie D., and Cassell M. Neurotransmission in the rat amygdala related to fear and anxiety. Trends Neurosci 17 (1994) 208-214
8. de Bruin N.M., Ellenbroek B.A., Cools A.R., Coenen A.M., and van Luijtelaar E.L. Differential effects of ketamine on gating of auditory evoked potentials and prepulse inhibition in rats. Psychopharmacology (Berl) 142 (1999) 9-17
9. Doronbekov T.K., Tokunaga H., Ikejiri Y., Kazui H., Hatta N., Masaki Y., et al. Neural basis of fear conditioning induced by video clip: positron emission tomography study. Psychiatry Clin Neurosci 59 (2005) 155-162
10. Dunn A.J., Swiergiel A.H., and Palamarchouk V. Brain circuits involved in corticotropin-releasing factor-norepinephrine interactions during stress. Ann N Y Acad Sci 1018 (2004) 25-34
11. Fanselow M.S., and Kim J.J. Acquisition of contextual Pavlovian fear conditioning is blocked by application of an NMDA receptor antagonist d,l-2-amino-5-phosphonovaleric acid to the basolateral amygdala. Behav Neurosci 108 (1994) 210-212
12. Frankland P.W., Bontempi B., Talton L.E., Kaczmarek L., and Silva A.J. The involvement of the anterior cingulate cortex in remote contextual fear memory. Science 304 (2004) 881-883
13. Gao Y.J., Ren W.H., Zhang Y.Q., and Zhao Z.Q. Contributions of the anterior cingulate cortex and amygdala to pain- and fear-conditioned place avoidance in rats. Pain 110 (2004) 343-353
14. Goosens K.A., and Maren S. Pretraining NMDA receptor blockade in the basolateral complex, but not the central nucleus, of the amygdala prevents savings of conditional fear. Behav Neurosci 117 (2003) 738-750
15. Imre G., Fokkema D.S., Boer J.A., and Ter Horst G.J. Dose-response characteristics of ketamine effect on locomotion, cognitive function and central neuronal activity. Brain Res Bull 69 3 (2006) 338-345
16. Kim M., and McGaugh J.L. Effects of intra-amygdala injections of NMDA receptor antagonists on acquisition and retention of inhibitory avoidance. Brain Res 585 (1992) 35-48
17. Koo J.W., Han J.S., and Kim J.J. Selective neurotoxic lesions of basolateral and central nuclei of the amygdala produce differential effects on fear conditioning. J Neurosci 24 (2004) 7654-7662
18. LeDoux J.E. Brain mechanisms of emotion and emotional learning. Curr Opin Neurobiol 2 (1992) 191-197
19. LeDoux J. Fear and the brain: where have we been, and where are we going?. Biol Psychiatry 44 (1998) 1229-1238
20. LeDoux J.E. Emotion circuits in the brain. Annu Rev Neurosci 23 (2000) 155-184
21. Lee H.J., Choi J.S., Brown T.H., and Kim J.J. Amygdalar nmda receptors are critical for the expression of multiple conditioned fear responses. J Neurosci 21 (2001) 4116-4124
22. Levita L., Dalley J.W., and Robbins T.W. Nucleus accumbens dopamine and learned fear revisited: a review and some new findings. Behav Brain Res 137 (2002) 115-127
23. Li X.F., Phillips R., and LeDoux J.E. NMDA and non-NMDA receptors contribute to synaptic transmission between the medial geniculate body and the lateral nucleus of the amygdala. Exp Brain Res 105 (1995) 87-100
24. Maren S. Neurobiology of Pavlovian fear conditioning. Annu Rev Neurosci 24 (2001) 897-931
25. Maren S., and Fanselow M.S. The amygdala and fear conditioning: has the nut been cracked?. Neuron 16 (1996) 237-240
26. Miserendino M.J., Sananes C.B., Melia K.R., and Davis M. Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala. Nature 345 (1990) 716-718
27. Morrow B.A., Elsworth J.D., and Roth R.H. Fear-like biochemical and behavioral responses in rats to the predator odor, TMT, are dependent on the exposure environment. Synapse 46 (2002) 11-18
28. Nash Jr. J.F., and Maickel R.P. The role of the hypothalamic-pituitary-adrenocortical axis in post-stress induced ethanol consumption by rats. Prog Neuropsychopharmacol Biol Psychiatry 12 (1988) 653-671
29. Pallares M.A., Nadal R.A., Silvestre J.S., and Ferre N.S. Effects of ketamine, a noncompetitive NMDA antagonist, on the acquisition of the lever-press response in rats. Physiol Behav 57 (1995) 389-392
30. Paradiso S., Andreasen N.C., Crespo-Facorro B., O'Leary D.S., Watkins G.L., Boles Ponto L.L., et al. Emotions in unmedicated patients with schizophrenia during evaluation with positron emission tomography. Am J Psychiatry 160 (2003) 1775-1783
31. Phillips R.G., and LeDoux J.E. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci 106 (1992) 274-285
32. Pietersen C.Y., Bosker F.J., Postema F., and den Boer J.A. Fear conditioning and shock intensity: the choice between minimizing the stress induced and reducing the number of animals used. Lab Anim 40 (2006) 180-185
33. Reynolds S.M., and Berridge K.C. Glutamate motivational ensembles in nucleus accumbens: rostrocaudal shell gradients of fear and feeding. Eur J Neurosci 17 (2003) 2187-2200
34. Sachs G., Steger-Wuchse D., Kryspin-Exner I., Gur R.C., and Katschnig H. Facial recognition deficits and cognition in schizophrenia. Schizophr Res 68 (2004) 27-35
35. Salamone J.D., Correa M., Mingote S.M., and Weber S.M. Beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine. Curr Opin Pharmacol 5 (2005) 34-41
36. Schauz C., and Koch M. Blockade of NMDA receptors in the amygdala prevents latent inhibition of fear-conditioning. Learn Mem 7 (2000) 393-399
37. Sharp J.L., Zammit T.G., Azar T.A., and Lawson D.M. Stress-like responses to common procedures in male rats housed alone or with other rats. Contemp Top Lab Anim Sci 41 (2002) 8-14
38. Suzuki T., Ishigooka J., Watanabe S., and Miyaoka H. Enhancement of delayed release of dopamine in the amygdala induced by conditioned fear stress in methamphetamine-sensitized rats. Eur J Pharmacol 435 (2002) 59-65
39. Swanson L.W. Brain maps: structure of the rat brain (1992), Elsevier Publishing Company, Amsterdam
40. Swanson C.J., Bures M., Johnson M.P., Linden A.M., Monn J.A., and Schoepp D.D. Metabotropic glutamate receptors as novel targets for anxiety and stress disorders. Nat Rev Drug Discov 4 (2005) 131-144
41. Takahashi H., Koeda M., Oda K., Matsuda T., Matsushima E., Matsuura M., et al. An fMRI study of differential neural response to affective pictures in schizophrenia. NeuroImage 22 (2004) 1247-1254
42. Tang J., Ko S., Ding H.K., Qiu C.S., Calejesan A.A., and Zhuo M. Pavlovian fear memory induced by activation in the anterior cingulate cortex. Mol Pain 1 (2005) 6
43. Thiels E., and Klann E. Hippocampal memory and plasticity in superoxide dismutase mutant mice. Physiol Behav 77 (2002) 601-605
44. Tsai G., and Coyle J.T. Glutamatergic mechanisms in schizophrenia. Annu Rev Pharmacol Toxicol 42 (2002) 165-179
45. Walker D.L., and Davis M. The role of amygdala glutamate receptors in fear learning, fear-potentiated startle, and extinction. Pharmacol Biochem Behav 71 (2002) 379-392