Mechanism of signal transduction of differentiation of mesenchymal stem cells into cytokeratin-expressing epidermoid cells

National Medical Journal of China

Volumn 86, Issue 18, 2006, Pages 1269-1273

  Bai, Xiao Dong ^a   Fu, Xiao Bing ^b   Zhang, Qi ^b   Sun, Tong Zhu ^b  

^a GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

^b NONE

Author keywords

Epidermis; Mesenchymal stem cells; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA1 INTEGRIN; CD34 ANTIGEN; CD45 ANTIGEN; CYTOKERATIN; CYTOKERATIN 19; CYTOKERATIN 5; EPIDERMAL GROWTH FACTOR; FASUDIL; HERMES ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; RHO FACTOR; SUGAR; SYNAPTOPHYSIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SEPARATION; CELL STIMULATION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME INHIBITION; EPIDERMIS CELL; FIBROBLAST; IMMUNOCYTOCHEMISTRY; LYMPHOCYTE; MESENCHYMAL STEM CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; SUPERNATANT;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; ANTIGENS, CD29; ANTIGENS, CD44; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; EPIDERMAL GROWTH FACTOR; EPIDERMIS; FEMALE; FLAVONOIDS; FLOW CYTOMETRY; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; KERATIN-19; KERATINS; MALE; MECHANOTRANSDUCTION, CELLULAR; MESENCHYMAL STEM CELLS; PYRIDINES; RATS; RATS, WISTAR; TIME FACTORS;

EID: 33747052320     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Pittenger MF, Mackay AM, Beck SC, et al. Mutilineage potential of adult human mesenchymal stem cells. Science, 1999, 284: 143-147.
2. Krause DS, Theise ND, Collector MI, et al. Muti-organ, mutilineage engraftment by a single bone marrow-derived stem cell. Cell, 2001, 105:369-377.
3. Chinese source. 2003,19:212-214.
4. Bruder SP, Kurth AA, Shea M, et al. Bone regeneration by implantation of purified, culture-expanded human mesenchymal stem cells. J Orthop Res, 1998,16:155-162.
5. Chinese source. 2002,82:1632-1636.
6. Chinese source. 2004,84:1332.
7. Chinese source. 2005,85:1885-1889.
8. Chinese source. 2003,19:22-24.
9. Chinese source. 2004,84:920-924.
10. Fuchs E, Tumbar T, Guasch G, et al. Socializing with the neighbors stem cells and their niche. Cell, 2004,116:769-778.
11. Watt FM, Hogan BL. Out of Eden: stem cells and their niches. Science, 2000,287:1427-1430.
12. Roelen BA, Dijke P. Controlling mesenchymal stem cell differentiation by TGFbeta family members. J Orthop Sci, 2003,8: 740-748.
13. Rojas M, Xu J, Woods CR, et al. Bone marrow derived mesenchymal stem cells in repair of the injured lung. Am J Respir Cell Mol Biol, 2005,33:145-152.
14. Cool SM, Nurcombe V. The osteoblast heparan sulfate axis: control of the bone cell lineage. Int J Biochem Cell Biol, 2005,37:1739-1745.
15. Kratchmarova I, Blagoev B, Haack SM, et al. Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation. Science, 2005,308:1472-1477.
16. Park JS, Kim HY, Kim HW, et al. Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesencymal stem cell. Mech Ageing Dev, 2005,126:551-559.
17. Lang D, Lu MM, Huang I, et al. Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature, 2005,433:884-887.
18. Jaiswal RK, Jaiswal N, Bruder SP, et al. Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase. J Biol Chem, 2000, 275: 9645-9652.
19. Sordella R, Jiang W, Chen GC, et al. Modulation of Rho GTPase signaling regulates a switch between adiogenesis and myogenesis. Cell, 2003,113:147-158.
20. Mcbeath R, Pirone DM, Nelson CM, et al. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell, 2004,6:483-495.