Attacking β-amyloid at its source

Scientist

Volumn 16, Issue 2, 2002, Pages 25-26

  Maher, Brendan A ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33746975374     PISSN: 08903670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. N.S. Halim, "Elusive β-secretase identified," The Scientist 14[13]:6, June 26, 2000.
2. I. Okamoto et al., "Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway," Journal of Cell Biology, 155[5]755-62, Nov. 26, 2001.
3. C-Y. Ni et al., "γ secretase cleavage and nuclear localization of ErbB-4 receptor tyro sine kinase," Science, 294:2179-81, Dec 7, 2001.
4. R. Vassar et al., "β-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE," Science, 286:735-41, 1999.
5. L. Hong et al., "Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor," Science, 290:150-3, 2000.
6. S. Kitazume et al., "Alzheimer's β-secretase, β-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase," Proceedings of the National Academy of Sciences, 98:13554-9 Nov. 20, 2001.