A novel, antimicrobially active analog of gramicidin S without amphiphilic conformation

Journal of Antibiotics

Volumn 59, Issue 6, 2006, Pages 370-372

  Tamaki, Makoto ^a   Sawa, Kenta ^a   Kikuchi, Sho ^a   Shindo, Mitsuno ^b   Uchida, Yoshiki ^b  

^a TOHO UNIVERSITY   (Japan)

^b OSAKA SHOIN WOMEN'S UNIVERSITY   (Japan)

Author keywords

A potent cyclotetradecapeptide antibiotic; Antiparallel sheet conformation; Circular dichroism; Gramicidin S analog; NMR; No amphiphilic character

Indexed keywords

AMPHOPHILE; ANTIINFECTIVE AGENT; CYCLO(VALYLLEUCYLLEUCYL ORNITHINE LEUCYL DEXTRO PHENYLALANYLPROLINE)2; GRAMICIDIN S; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS MEGATERIUM; BETA SHEET; CIRCULAR DICHROISM; CONFORMATION; CONTROLLED STUDY; DRUG SENSITIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; GRAMICIDIN; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP;

BACILLUS MEGATERIUM; POSIBACTERIA;

EID: 33746919609     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2006.54     Document Type: Article

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