Dynamic changes in chromatin acetylation and the expression of histone acetyltransferases and histone deacetylases regulate the SM22α transcription in response to Smad3-mediated TGFβ1 signaling

Biochemical and Biophysical Research Communications

Volumn 348, Issue 2, 2006, Pages 351-358

  Qiu, Ping ^a   Ritchie, Raquel P ^a   Gong, Xue Qian ^a   Hamamori, Yasuo ^b   Li, Li ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Histone acetylation; Myocardin; SM22; Smad3; TGF 1; TSA

Indexed keywords

HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; MYOCARDIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSCRIPTION FACTOR TWIST; TRANSFORMING GROWTH FACTOR BETA1;

ACETYLATION; AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG EFFECT; GENE LOCUS; GENETIC TRANSCRIPTION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TRANSCRIPTION INITIATION;

ACETYLATION; ANIMALS; CELL LINE; CHROMATIN; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASES; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; NUCLEAR PROTEINS; P300-CBP TRANSCRIPTION FACTORS; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 33746912681     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.07.009     Document Type: Article

References (45)

1. Grainger D.J. Transforming growth beta and factor atherosclerosis: so far, so good for the protective cytokine hypothesis. Arterioscler. Thromb. Vasc. Biol. 24 (2004) 399-404
2. Feng X.H., and Derynck R. Specificity and versatility in TGF-signaling through Smads. Annu. Rev. Cell. Dev. Biol. (2005)
3. Chen S., and Lechleider R.J. Transforming growth factor-beta-induced differentiation of smooth muscle from a neural crest stem cell line. Circ. Res. 94 (2004) 1195-1202
4. Qiu P., Feng X.H., and Li L. Interaction of Smad3 and SRF-associated complex mediates TGF-beta1 signals to regulate SM22 transcription during myofibroblast differentiation. J. Mol. Cell. Cardiol. 35 (2003) 1407-1420
5. Hu B., Wu Z., and Phan S.H. Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression. Am. J. Respir. Cell Mol. Biol. 29 (2003) 397-404
6. Chen S., Kulik M., and Lechleider R.J. Smad proteins regulate transcriptional induction of the SM22alpha gene by TGF-beta. Nucleic Acids Res. 31 (2003) 1302-1310
7. Sinha S., Hoofnagle M.H., Kingston P.A., McCanna M.E., and Owens G.K. Transforming growth factor-beta1 signaling contributes to development of smooth muscle cells from embryonic stem cells. Am. J. Physiol. Cell Physiol. 287 (2004) C1560-C1568
8. Qiu P., Ritchie R.P., Fu Z., Cao D., Cumming J., Miano J.M., Wang D.Z., Li H.J., and Li L. Myocardin enhances Smad3-mediated transforming growth factor-beta1 signaling in a CArG box-independent manner: Smad-binding element is an important cis element for SM22alpha transcription in vivo. Circ. Res. 97 (2005) 983-991
9. Subramanian S.V., Polikandriotis J.A., Kelm Jr. R.J., David J.J., Orosz C.G., and Strauch A.R. Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators. Mol. Biol. Cell. 15 (2004) 4532-4543
10. Jenuwein T., and Allis C.D. Translating the histone code. Science 293 (2001) 1074-1080
11. Yang X.J. Multisite protein modification and intramolecular signaling. Oncogene 24 (2005) 1653-1662
12. Backs J., and Olson E.N. Control of cardiac growth by histone acetylation/deacetylation. Circ. Res. 98 (2006) 15-24
13. McKinsey T.A., and Olson E.N. Dual roles of histone deacetylases in the control of cardiac growth. Novartis Found. Symp. 259 (2004) 132-141
14. Qiu P., and Li L. Histone acetylation and recruitment of serum responsive factor and CREB-binding protein onto SM22 promoter during SM22 gene expression. Circ. Res. 90 (2002) 858-865
15. Ramirez S., Ait-Si-Ali S., Robin P., Trouche D., Harel-Bellan A., and Ait Si Ali S. The CREB-binding protein (CBP) cooperates with the serum response factor for transactivation of the c-fos serum response element. J. Biol. Chem. 272 (1997) 31016-31021
16. Cao D., Wang Z., Zhang C.L., Oh J., Xing W., Li S., Richardson J.A., Wang D.Z., and Olson E.N. Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol. Cell. Biol. 25 (2005) 364-376
17. Illi B., Scopece A., Nanni S., Farsetti A., Morgante L., Biglioli P., Capogrossi M.C., and Gaetano C. Epigenetic histone modification and cardiovascular lineage programming in mouse embryonic stem cells exposed to laminar shear stress. Circ. Res. 96 (2005) 501-508
18. Manabe I., and Owens G.K. Recruitment of serum response factor and hyperacetylation of histones at smooth muscle-specific regulatory regions during differentiation of a novel P19-derived in vitro smooth muscle differentiation system. Circ. Res. 88 (2001) 1127-1134
19. McDonald O.G., Wamhoff B.R., Hoofnagle M.H., and Owens G.K. Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo. J. Clin. Invest. 116 (2006) 36-48
20. Alberts A.S., Geneste O., and Treisman R. Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation. Cell 92 (1998) 475-487
21. Hirschi K.K., Rohovsky S.A., and D'Amore P.A. PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate. [published erratum appears in J. Cell Biol. Jun 1;141(5) (1998) 1287]. J. Cell Biol. 141 (1998) 805-814
22. Tomasek J.J., Gabbiani G., Hinz B., Chaponnier C., and Brown R.A. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat. Rev. Mol. Cell. Biol. 3 (2002) 349-363
23. Li L., Cserjesi P., and Olson E.N. Dermo-1: a novel twist-related bHLH protein expressed in the developing dermis. Dev. Biol. 172 (1995) 280-292
24. Li L., Miano J.M., Mercer B., and Olson E.N. Expression of the SM22alpha promoter in transgenic mice provides evidence for distinct transcriptional regulatory programs in vascular and visceral smooth muscle cells. J. Cell Biol. 132 (1996) 849-859
25. Gong X.Q., and Li L. Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation. J. Biol. Chem. 277 (2002) 12310-12317
26. Yang W.M., Yao Y.L., Sun J.M., Davie J.R., and Seto E. Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. J. Biol. Chem. 272 (1997) 28001-28007
27. Wu H., and Olson E.N. Activation of the MEF2 transcription factor in skeletal muscles from myotonic mice. J. Clin. Invest. 109 (2002) 1327-1333
28. Hamamori Y., Sartorelli V., Ogryzko V., Puri P.L., Wu H.Y., Wang J.Y., Nakatani Y., and Kedes L. Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A. Cell 96 (1999) 405-413
29. Wang D., Chang P.S., Wang Z., Sutherland L., Richardson J.A., Small E., Krieg P.A., and Olson E.N. Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell 105 (2001) 851-862
30. Weinstein M., Yang X., and Deng C. Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. Cytokine Growth Factor Rev. 11 (2000) 49-58
31. Pan D., Zhe X., Jakkaraju S., Taylor G.A., and Schuger L. P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype. J. Clin. Invest. 110 (2002) 1349-1358
32. Hautmann M.B., Adam P.J., and Owens G.K. Similarities and differences in smooth muscle alpha-actin induction by TGF-beta in smooth muscle versus non-smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 19 (1999) 2049-2058
33. Jain M.K., Layne M.D., Watanabe M., Chin M.T., Feinberg M.W., Sibinga N.E., Hsieh C.M., Yet S.F., Stemple D.L., and Lee M.E. In vitro system for differentiating pluripotent neural crest cells into smooth muscle cells. J. Biol. Chem. 273 (1998) 5993-5996
34. Euler-Taimor G., and Heger J. The complex pattern of SMAD signaling in the cardiovascular system. Cardiovasc. Res. 69 (2006) 15-25
35. Kobayashi T., Liu X., Wen F.Q., Kohyama T., Shen L., Wang X.Q., Hashimoto M., Mao L., Togo S., Kawasaki S., Sugiura H., Kamio K., and Rennard S.I. Smad3 mediates TGF-beta1-induced collagen gel contraction by human lung fibroblasts. Biochem. Biophys. Res. Commun. 339 (2006) 290-295
36. Dunn N.R., Vincent S.D., Oxburgh L., Robertson E.J., and Bikoff E.K. Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo. Development 131 (2004) 1717-1728
37. Wang Y., Fischle W., Cheung W., Jacobs S., Khorasanizadeh S., and Allis C.D. Beyond the double helix: writing and reading the histone code. Novartis Found. Symp. 259 (2004) 3-17 discussion 17-21, 163-169
38. Fu M., Wang C., Wang J., Zafonte B.T., Lisanti M.P., and Pestell R.G. Acetylation in hormone signaling and the cell cycle. Cytokine Growth Factor Rev. 13 (2002) 259-276
39. Kumar M.S., and Owens G.K. Combinatorial control of smooth muscle-specific gene expression. Arterioscler. Thromb. Vasc. Biol. 23 (2003) 737-747
40. Miano J.M. Serum response factor: toggling between disparate programs of gene expression. J. Mol. Cell. Cardiol. 35 (2003) 577-593
41. Wang D.Z., and Olson E.N. Control of smooth muscle development by the myocardin family of transcriptional coactivators. Curr. Opin. Genet. Dev. 14 (2004) 558-566
42. Janknecht R., Wells N.J., and Hunter T. TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300. Genes Dev. 12 (1998) 2114-2119
43. McKinsey T.A., Zhang C.L., and Olson E.N. Signaling chromatin to make muscle. Curr. Opin. Cell. Biol. 14 (2002) 763-772
44. Kumar M.S., Hendrix J.A., Johnson A.D., and Owens G.K. Smooth muscle alpha-actin gene requires two E-boxes for proper expression in vivo and is a target of class I basic helix-loop-helix proteins. Circ. Res. 92 (2003) 840-847
45. Ma K., Chan J.K., Zhu G., and Wu Z. Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation. Mol. Cell. Biol. 25 (2005) 3575-3582