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Volumn 397, Issue 3, 2006, Pages 509-518

Disruption of inositol biosynthesis through targeted mutagenesis in Dictyostelium discoideum: Generation and characterization of inositol-auxotrophic mutants

Author keywords

2,3 bisphosphoglycerate; Dictyostelium; Gene disruption; Inositol auxotrophy; Inositol 3 phosphate synthase; Phosphoinositide

Indexed keywords

BACTERIOPHAGES; BIOSYNTHESIS; CELLS; ENZYME INHIBITION; MUTAGENESIS; PHOSPHATES; PHYSIOLOGY;

EID: 33746895424     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060277     Document Type: Article
Times cited : (15)

References (48)
  • 1
    • 0141682777 scopus 로고    scopus 로고
    • Diversification and evolution of L-myo-inositol 1-phosphate synthase
    • Majumder, A. L., Chatterjee, A., Dastidar, K. G. and Majee, M. (2003) Diversification and evolution of L-myo-inositol 1-phosphate synthase. FEBS Lett. 553, 3-10
    • (2003) FEBS Lett. , vol.553 , pp. 3-10
    • Majumder, A.L.1    Chatterjee, A.2    Dastidar, K.G.3    Majee, M.4
  • 3
    • 0034764722 scopus 로고    scopus 로고
    • The promise of a protiste: The Dictyostelium genome project
    • Kuspa, A., Sucgang, R. and Shaulsky, G. (2001) The promise of a protiste: the Dictyostelium genome project. Funct. Integr. Genomics 1, 279-293
    • (2001) Funct. Integr. Genomics , vol.1 , pp. 279-293
    • Kuspa, A.1    Sucgang, R.2    Shaulsky, G.3
  • 4
    • 0035347166 scopus 로고    scopus 로고
    • Back in the water: The return of the inositol phosphates
    • Irvine, R. F. and Schell, M. J. (2001) Back in the water: the return of the inositol phosphates. Nat. Rev. Mol. Cell Biol. 2, 327-338
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 327-338
    • Irvine, R.F.1    Schell, M.J.2
  • 5
    • 0035975965 scopus 로고    scopus 로고
    • Modular phosphoinositide-binding domains - Their role in signalling and membrane trafficking
    • Cullen, P. J., Cozier, G. E., Banting, G. and Mellor, H. (2001) Modular phosphoinositide-binding domains - their role in signalling and membrane trafficking. Curr. Biol. 11, R882-R893
    • (2001) Curr. Biol. , vol.11
    • Cullen, P.J.1    Cozier, G.E.2    Banting, G.3    Mellor, H.4
  • 6
    • 0017493805 scopus 로고
    • A defined minimal medium for axenic strains of Dictyostelium discoideum
    • Franke, J. and Kessin, R. (1977) A defined minimal medium for axenic strains of Dictyostelium discoideum. Proc. Natl. Acad. Sci. U.S.A. 74, 2157-2161
    • (1977) Proc. Natl. Acad. Sci. U.S.A. , vol.74 , pp. 2157-2161
    • Franke, J.1    Kessin, R.2
  • 7
    • 0030738316 scopus 로고    scopus 로고
    • Biochemistry and genetics of inositol metabolism in Dictyostelium
    • Van Haastert, P. J. M. and Van Dijken, P. (1997) Biochemistry and genetics of inositol metabolism in Dictyostelium. FEBS Lett. 410, 39-43
    • (1997) FEBS Lett. , vol.410 , pp. 39-43
    • Van Haastert, P.J.M.1    Van Dijken, P.2
  • 8
    • 0029147402 scopus 로고
    • A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: Biological roles of putative mammalian p110 and yeast VPs34p PI 3-kinase homologs during growth and development
    • Zhou, K., Takegawa, K., Emr, S. D. and Firtel, R. A. (1995) A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast VPs34p PI 3-kinase homologs during growth and development. Mol. Cell. Biol. 15, 5645-5656
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5645-5656
    • Zhou, K.1    Takegawa, K.2    Emr, S.D.3    Firtel, R.A.4
  • 9
    • 0037458725 scopus 로고    scopus 로고
    • A diverse family of inositol 5-phosphatases playing a role in growth and development in Dictyostelium discoideum
    • Loovers, H. M., Veenstra, K., Snippe, H., Pesesse, X., Erneux, Ch. and Van Haastert, P. J. M. (2003) A diverse family of inositol 5-phosphatases playing a role in growth and development in Dictyostelium discoideum. J. Biol. Chem. 278, 5652-5658
    • (2003) J. Biol. Chem. , vol.278 , pp. 5652-5658
    • Loovers, H.M.1    Veenstra, K.2    Snippe, H.3    Pesesse, X.4    Erneux, Ch.5    Van Haastert, P.J.M.6
  • 10
    • 0034010804 scopus 로고    scopus 로고
    • Diphospho-myo-inositol phosphates during the life cycle of Dictyostelium and Polysphondylium
    • Laussmann, T., Pikzack, C., Thiel, U., Mayr, G. W. and Vogel, G. (2000) Diphospho-myo-inositol phosphates during the life cycle of Dictyostelium and Polysphondylium. Eur. J. Biochem. 267, 2447-2451
    • (2000) Eur. J. Biochem. , vol.267 , pp. 2447-2451
    • Laussmann, T.1    Pikzack, C.2    Thiel, U.3    Mayr, G.W.4    Vogel, G.5
  • 11
    • 0014841120 scopus 로고
    • Growth of myxameobae of the cellular slime mould Dictyostelium discoideum in axenic culture
    • Watts, D. J. and Ashworth, J. M. (1970) Growth of myxameobae of the cellular slime mould Dictyostelium discoideum in axenic culture. Biochem. J. 119, 171-174
    • (1970) Biochem. J. , vol.119 , pp. 171-174
    • Watts, D.J.1    Ashworth, J.M.2
  • 12
    • 0023073916 scopus 로고
    • Cultivation and synchronous morphogenesis of Dictyostelium under controlled experimental conditions
    • (Spudich, J. A., ed.), Academic Press, New York
    • Sussman, M. (1987) Cultivation and synchronous morphogenesis of Dictyostelium under controlled experimental conditions. In Methods in Cell Biology, vol. 28 (Spudich, J. A., ed.), pp. 9-29, Academic Press, New York
    • (1987) Methods in Cell Biology , vol.28 , pp. 9-29
    • Sussman, M.1
  • 13
    • 0018516170 scopus 로고
    • Photoaffinity labeling of cyclic-AMP- and AMP-binding proteins in differentiating Dictyostelium discoideum cells
    • Wallace, L. J. and Frazier, W. A. (1979) Photoaffinity labeling of cyclic-AMP- and AMP-binding proteins in differentiating Dictyostelium discoideum cells. Proc. Natl. Acad. Sci. U.S.A. 76, 4250-4254
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 4250-4254
    • Wallace, L.J.1    Frazier, W.A.2
  • 14
    • 0028670206 scopus 로고
    • Isolation of Dictyostelium discoideum cytokinesis mutants by restriction enzyme-mediated integration of the blasticidin S resistance marker
    • Adachi, H., Hasebe, T., Yoshinaga, K., Ohta, T. and Sutoh, K. (1994) Isolation of Dictyostelium discoideum cytokinesis mutants by restriction enzyme-mediated integration of the blasticidin S resistance marker. Biochem. Biophys. Res. Commun. 205, 1808-1814
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 1808-1814
    • Adachi, H.1    Hasebe, T.2    Yoshinaga, K.3    Ohta, T.4    Sutoh, K.5
  • 15
    • 0026650509 scopus 로고
    • Overexpression of the csA cell adhesion molecule under its own cAMP-regulated promoter impairs morphogenesis in Dictyostelium
    • Faix, J., Gerisch, G. and Noegel, A. A. (1992) Overexpression of the csA cell adhesion molecule under its own cAMP-regulated promoter impairs morphogenesis in Dictyostelium. J. Cell Sci. 102, 203-214
    • (1992) J. Cell Sci. , vol.102 , pp. 203-214
    • Faix, J.1    Gerisch, G.2    Noegel, A.A.3
  • 16
    • 0019305482 scopus 로고
    • Mechanism of phagocytosis in Dictyostelium discoideum: Phagocytosis is mediated by different recognition sites as disclosed by mutants with altered phagocytotic properties
    • Vogel, G., Thilo, L., Schwarz, H. and Steinhart, R. (1980) Mechanism of phagocytosis in Dictyostelium discoideum: phagocytosis is mediated by different recognition sites as disclosed by mutants with altered phagocytotic properties. J. Cell Biol. 86, 456-465
    • (1980) J. Cell Biol. , vol.86 , pp. 456-465
    • Vogel, G.1    Thilo, L.2    Schwarz, H.3    Steinhart, R.4
  • 17
    • 0038181194 scopus 로고    scopus 로고
    • Stereoselective synthesis of myo-, neo-, L-chiro-, D-chiro-, allo-, scyllo-, and epi-inositol systems via conduritols prepared from p-benzoquinone
    • Podeschwa, M., Plettenburg, O., vom Brocke, J., Block, O., Adelt, S. and Altenbach, H. J. (2003) Stereoselective synthesis of myo-, neo-, L-chiro-, D-chiro-, allo-, scyllo-, and epi-inositol systems via conduritols prepared from p-benzoquinone. Eur. J. Org. Chem. 10, 1958-1972
    • (2003) Eur. J. Org. Chem. , vol.10 , pp. 1958-1972
    • Podeschwa, M.1    Plettenburg, O.2    Vom Brocke, J.3    Block, O.4    Adelt, S.5    Altenbach, H.J.6
  • 18
    • 0019554465 scopus 로고
    • Alkaline O → N-transacylation: A new method for the quantitative deacylation of phospholipids
    • Clarke, N. G. and Dawson, R. M. (1981) Alkaline O → N-transacylation: a new method for the quantitative deacylation of phospholipids. Biochem. J. 195, 301-306
    • (1981) Biochem. J. , vol.195 , pp. 301-306
    • Clarke, N.G.1    Dawson, R.M.2
  • 19
    • 0037083398 scopus 로고    scopus 로고
    • Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection
    • Nasuhoglu, C., Feng, S., Mao, J., Yamamoto, M., Yin, H. L., Earnest, S., Barylko, B., Albanesi, J. P. and Hilgemann, D. W. (2002) Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection. Anal. Biochem. 301, 243-254
    • (2002) Anal. Biochem. , vol.301 , pp. 243-254
    • Nasuhoglu, C.1    Feng, S.2    Mao, J.3    Yamamoto, M.4    Yin, H.L.5    Earnest, S.6    Barylko, B.7    Albanesi, J.P.8    Hilgemann, D.W.9
  • 20
    • 0024075976 scopus 로고
    • A novel metal-dye-detection system permits picomolar-range h.p.l.c. analysis of inositol polyphosphates from non-radioactively labelled cell or tissue specimens
    • Mayr, G. W. (1988) A novel metal-dye-detection system permits picomolar-range h.p.l.c. analysis of inositol polyphosphates from non-radioactively labelled cell or tissue specimens. Biochem. J. 254, 585-591
    • (1988) Biochem. J. , vol.254 , pp. 585-591
    • Mayr, G.W.1
  • 21
    • 0033535534 scopus 로고    scopus 로고
    • Enzyme-assisted total synthesis of the optical antipodes D-myo-inositol 3,4,5-trisphosphate and D-myo-inositol 1,5,6-trisphosphate: Aspects of their structure-activity relationship to biologically active inositol phosphates
    • Adelt, S., Plettenburg, O., Stricker, R., Reiser, G., Altenbach, H. J. and Vogel, G. (1999) Enzyme-assisted total synthesis of the optical antipodes D-myo-inositol 3,4,5-trisphosphate and D-myo-inositol 1,5,6-trisphosphate: aspects of their structure-activity relationship to biologically active inositol phosphates. J. Med. Chem. 42, 1262-1273
    • (1999) J. Med. Chem. , vol.42 , pp. 1262-1273
    • Adelt, S.1    Plettenburg, O.2    Stricker, R.3    Reiser, G.4    Altenbach, H.J.5    Vogel, G.6
  • 23
    • 0024075975 scopus 로고
    • Two dephosphorylation pathways of inositol 1,4,5-trisphosphate in homogenates of the cellular slime mould Dictyostelium discoideum
    • Van Lookeren Campagne, M. M., Erneux, C., Van Eijk, R. and Van Haastert, P. J. M. (1988) Two dephosphorylation pathways of inositol 1,4,5-trisphosphate in homogenates of the cellular slime mould Dictyostelium discoideum. Biochem. J. 254, 343-350
    • (1988) Biochem. J. , vol.254 , pp. 343-350
    • Van Lookeren Campagne, M.M.1    Erneux, C.2    Van Eijk, R.3    Van Haastert, P.J.M.4
  • 25
    • 0017579105 scopus 로고
    • Growth and metabolism of inositol-starved Saccharomyces cerevisiae
    • Henry, S. A., Atkinson, K. D., Kolat, A. I. and Culbertson, M. R. (1977) Growth and metabolism of inositol-starved Saccharomyces cerevisiae. J. Bacteriol. 130, 472-484
    • (1977) J. Bacteriol. , vol.130 , pp. 472-484
    • Henry, S.A.1    Atkinson, K.D.2    Kolat, A.I.3    Culbertson, M.R.4
  • 26
    • 0018367448 scopus 로고
    • Lipid and cell wall changes in an inositol-requiring mutant of Neurospora crassa
    • Hanson, B. and Brody, S. (1979) Lipid and cell wall changes in an inositol-requiring mutant of Neurospora crassa. J. Bacteriol. 138, 461-466
    • (1979) J. Bacteriol. , vol.138 , pp. 461-466
    • Hanson, B.1    Brody, S.2
  • 27
    • 0023806484 scopus 로고
    • Inositol metabolism and cell growth in a Chinese hamster ovary cell myo-inositol auxotroph
    • Jackowski, S., Voelker, D. R. and Rock, C. O. (1988) Inositol metabolism and cell growth in a Chinese hamster ovary cell myo-inositol auxotroph. J. Biol. Chem. 263, 16830-16836
    • (1988) J. Biol. Chem. , vol.263 , pp. 16830-16836
    • Jackowski, S.1    Voelker, D.R.2    Rock, C.O.3
  • 28
    • 0011017611 scopus 로고
    • The relationship of m-inositol to morphology in Neurospora crassa
    • Shatkin, A. J. and Tatum, E. L. (1961) The relationship of m-inositol to morphology in Neurospora crassa. Am. J. Bot. 48, 760-771
    • (1961) Am. J. Bot. , vol.48 , pp. 760-771
    • Shatkin, A.J.1    Tatum, E.L.2
  • 29
    • 0023075453 scopus 로고
    • The axenic mutations and endocytosis in Dictyostelium
    • Clarke, M. and Kayman, S. C. (1987) The axenic mutations and endocytosis in Dictyostelium. Methods Cell Biol. 28, 157-176
    • (1987) Methods Cell Biol. , vol.28 , pp. 157-176
    • Clarke, M.1    Kayman, S.C.2
  • 30
    • 0035042937 scopus 로고    scopus 로고
    • p110-related PI 3-kinases regulate phagosome-phagosome fusion and phagosomal pH through a PKB/Akt dependent pathway in Dictyostelium
    • Rupper, A. C., Rodriguez-Paris, J. M., Grove, B. D. and Cardelli, J. A. (2001) p110-related PI 3-kinases regulate phagosome-phagosome fusion and phagosomal pH through a PKB/Akt dependent pathway in Dictyostelium. J. Cell Sci. 114, 1283-1295
    • (2001) J. Cell Sci. , vol.114 , pp. 1283-1295
    • Rupper, A.C.1    Rodriguez-Paris, J.M.2    Grove, B.D.3    Cardelli, J.A.4
  • 31
    • 0343207804 scopus 로고
    • The developmental regulation of phosphatidylinositol kinase in Dictyostelium discoideum
    • Varela, I., Van Lookeren Campagne, M. M., Alvarez, J. F. and Mato, J. M. (1987) The developmental regulation of phosphatidylinositol kinase in Dictyostelium discoideum. FEBS Lett. 211, 64-68
    • (1987) FEBS Lett. , vol.211 , pp. 64-68
    • Varela, I.1    Van Lookeren Campagne, M.M.2    Alvarez, J.F.3    Mato, J.M.4
  • 33
    • 0033555931 scopus 로고    scopus 로고
    • A requirement for phosphatidylinositol 3-kinase in pseudopod extension
    • Cox, D., Tseng, C. C., Bjekic, G. and Greenberg, S. (1999) A requirement for phosphatidylinositol 3-kinase in pseudopod extension. J. Biol. Chem. 274, 1240-1247
    • (1999) J. Biol. Chem. , vol.274 , pp. 1240-1247
    • Cox, D.1    Tseng, C.C.2    Bjekic, G.3    Greenberg, S.4
  • 34
    • 24644452029 scopus 로고    scopus 로고
    • Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases
    • Stevenson-Paulik, J., Bastidas, R. J., Chiou, S.-T., Frye, R. A. and York, J. D. (2005) Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases. Proc. Natl. Acad. Sci. U.S.A. 102, 12612-12617
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 12612-12617
    • Stevenson-Paulik, J.1    Bastidas, R.J.2    Chiou, S.-T.3    Frye, R.A.4    York, J.D.5
  • 36
    • 20844440571 scopus 로고    scopus 로고
    • Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression
    • Verbsky, J., Lavine, K. and Majerus, Ph. W. (2005) Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression. Proc. Natl. Acad. Sci. U.S.A. 102, 8448-8453
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 8448-8453
    • Verbsky, J.1    Lavine, K.2    Majerus, Ph.W.3
  • 39
    • 0017688609 scopus 로고
    • Changes in phospholipids of Saccharomyces cerevisiae associated with inositol-less death
    • Becker, G. W. and Lester, R. L. (1977) Changes in phospholipids of Saccharomyces cerevisiae associated with inositol-less death. J. Biol. Chem. 252, 8684-8691
    • (1977) J. Biol. Chem. , vol.252 , pp. 8684-8691
    • Becker, G.W.1    Lester, R.L.2
  • 40
    • 0019050302 scopus 로고
    • The lipid composition and membrane fluidity of Dictyostelium discoideum plasma membranes at various stages during differentiation
    • Weeks, G. and Herring, F. G. (1980) The lipid composition and membrane fluidity of Dictyostelium discoideum plasma membranes at various stages during differentiation. J. Lipid Res. 21, 681-686
    • (1980) J. Lipid Res. , vol.21 , pp. 681-686
    • Weeks, G.1    Herring, F.G.2
  • 41
    • 0037449756 scopus 로고    scopus 로고
    • Fragmentation of the Golgi apparatus: A role for βIII spectrin and synthesis of phosphatidylinositol 4,5-bisphosphate
    • Siddhanta, A., Radulescu, A., Stankewicn, M. C., Morrow, J. S. and Shields, D. (2003) Fragmentation of the Golgi apparatus: a role for βIII spectrin and synthesis of phosphatidylinositol 4,5-bisphosphate. J. Biol. Chem. 278, 1957-1965
    • (2003) J. Biol. Chem. , vol.278 , pp. 1957-1965
    • Siddhanta, A.1    Radulescu, A.2    Stankewicn, M.C.3    Morrow, J.S.4    Shields, D.5
  • 42
    • 0028606474 scopus 로고
    • Purification and properties of phosphofructokinase from Dictyostelium discoideum
    • Martinez-Costa, O. H., Estevez, A. M., Sanchez, V. and Aragon, J. J. (1994) Purification and properties of phosphofructokinase from Dictyostelium discoideum. Eur. J. Biochem. 226, 1007-1017
    • (1994) Eur. J. Biochem. , vol.226 , pp. 1007-1017
    • Martinez-Costa, O.H.1    Estevez, A.M.2    Sanchez, V.3    Aragon, J.J.4
  • 43
    • 0023031893 scopus 로고
    • A possible role for glucose metabolites in the regulation of inositol-1,4,5-trisphosphate 5-phosphomonoesterase activity in pancreatic islets
    • Rana, R. S., Chandra Sekar, M., Hokin, L. E. and MacDonald, M. J. (1986) A possible role for glucose metabolites in the regulation of inositol-1,4,5-trisphosphate 5-phosphomonoesterase activity in pancreatic islets. J. Biol. Chem. 261, 5237-5240
    • (1986) J. Biol. Chem. , vol.261 , pp. 5237-5240
    • Rana, R.S.1    Chandra Sekar, M.2    Hokin, L.E.3    MacDonald, M.J.4
  • 44
    • 0024582989 scopus 로고
    • Inositol polyphosphate-mediated repartitioning of aldolase in skeletal muscle triads and myofibrils
    • Thieleczek, R., Mayr, G. W. and Brandt, N. R. (1989) Inositol polyphosphate-mediated repartitioning of aldolase in skeletal muscle triads and myofibrils. J. Biol. Chem. 264, 7349-7356
    • (1989) J. Biol. Chem. , vol.264 , pp. 7349-7356
    • Thieleczek, R.1    Mayr, G.W.2    Brandt, N.R.3
  • 47
    • 29644439885 scopus 로고    scopus 로고
    • Genetic perturbation of glycolysis results in inhibition of de novo inositol biosynthesis
    • Shi, Y., Vaden, D. L., Ju, S., Ding, D., Geiger, J. H. and Greenberg, M. L. (2005) Genetic perturbation of glycolysis results in inhibition of de novo inositol biosynthesis. J. Biol. Chem. 280, 41805-41810
    • (2005) J. Biol. Chem. , vol.280 , pp. 41805-41810
    • Shi, Y.1    Vaden, D.L.2    Ju, S.3    Ding, D.4    Geiger, J.H.5    Greenberg, M.L.6
  • 48
    • 0036677944 scopus 로고    scopus 로고
    • Inositol and higher inositol phosphates in neural tissues: Homeostasis, metabolism and functional significance
    • Fisher, S. K., Novak, J. E. and Agranoff, B. W. (2002) Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance. J. Neurochem. 82, 736-754
    • (2002) J. Neurochem. , vol.82 , pp. 736-754
    • Fisher, S.K.1    Novak, J.E.2    Agranoff, B.W.3


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