Shivering in the cold: From mechanisms of fuel selection to survival

Journal of Applied Physiology

Volumn 100, Issue 5, 2006, Pages 1702-1708

  Haman, François ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Energy metabolism; Fuel selection; Shivering thermogenesis; Survival in the cold; Thermoregulation

Indexed keywords

BODY TEMPERATURE; CARBOHYDRATE METABOLISM; COLD; ELECTROMYOGRAPHY; ENERGY METABOLISM; HUMAN; HYPOTHERMIA; LIPID METABOLISM; MUSCLE FATIGUE; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; SHIVERING; SKELETAL MUSCLE; SURVIVAL; THERMOREGULATION; VASOCONSTRICTION;

BODY TEMPERATURE; BODY TEMPERATURE REGULATION; CARBOHYDRATE METABOLISM; COLD; ELECTROMYOGRAPHY; ENERGY METABOLISM; HUMANS; HYPOTHERMIA; LIPID METABOLISM; MUSCLE FATIGUE; MUSCLE, SKELETAL; SHIVERING; SURVIVAL; VASOCONSTRICTION;

EID: 33746895178     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01088.2005     Document Type: Review

References (43)

1. Bell DG, Tikuisis P, and Jacobs I. Relative intensity of muscular contraction during shivering. J Appl Physiol 72: 2336-2342, 1992.
2. Eyolfson DA, Tikuisis P, Xu X, Weseen G, and Giesbrecht GG. Measurement and prediction of peak shivering intensity in humans. Eur J Appl Physiol 84: 100-106, 2001. (Pubitemid 32177877)
3. Gale EA, Bennett T, Green JH, and MacDonald IA. Hypoglycaemia, hypothermia and shivering in man. Clin Sci (Lond) 61: 463-469, 1981. (Pubitemid 12243013)
4. Glickman-Weiss EL, Nelson AG, Hearon CM, Vasanthakumar SR, and Stringer BT. Does feeding regime affect physiologic and thermal responses during exposure to 8, 20, and 27°C? Eur J Appl Physiol 67: 30-34, 1993. (Pubitemid 23272200)
5. Glickman-Weiss EL, Nelson AG, Hearon CM, Windhauser M, and Heltz D. The thermogenic effect of carbohydrate feeding during exposure to 8, 12 and 27°C. Eur J Appl Physiol 68: 291-297, 1994. (Pubitemid 24138792)
6. Gorke K and Pierau FK. Initiation of muscle activity in spinalized pigeons during spinal cord cooling and warming. Pflügers Arch 381: 47-52, 1979.
7. Haight JSJ and Keating RW. Failure of thermoregulation in the cold during hypoglycaemia induced by exercise and ethanol. J Physiol 229: 87-97, 1973.
8. Haman F, Legault SR, Rakobowchuk M, Ducharme MB, and Weber JM. Effects of carbohydrate availability on sustained shivering. II. Relating muscle recruitment to fuel selection. J Appl Physiol 96: 41-49, 2004. (Pubitemid 38031980)
9. Haman F, Legault SR, and Weber JM. Fuel selection during intense shivering in humans: EMG pattern reflects carbohydrate oxidation. J Physiol 556: 305-313, 2004. (Pubitemid 38515185)
10. Haman F, Peronnet F, Kenny GP, Doucet E, Massicotte D, Lavoie C, and Weber JM. Effects of carbohydrate availability on sustained shivering. I. Oxidation of plasma glucose, muscle glycogen, and proteins. J Appl Physiol 96: 32-40, 2004. (Pubitemid 38031979)
11. Haman F, Peronnet F, Kenny GP, Massicotte D, Lavoie C, Scott C, and Weber JM. Effect of cold exposure on fuel utilization in humans: plasma glucose, muscle glycogen, and lipids. J Appl Physiol 93: 77-84, 2002. (Pubitemid 34686196)
12. Haman F, Peronnet F, Kenny GP, Massicotte D, Lavoie C, and Weber JM. Partitioning oxidative fuels during cold exposure in humans: muscle glycogen becomes dominant as shivering intensifies. J Physiol 566: 247-256, 2005. (Pubitemid 40984218)
13. Herdman SJ. Recovery of shivering in spinal cats. Exp Neurol 59: 177-189, 1978. (Pubitemid 8313329)
14. Hohtola E and Stevens ED. The relationship of muscle electrical activity, tremor and heat production to shivering thermogenesis in Japanese quail. J Exp Biol 125: 119-135, 1986. (Pubitemid 16051916)
15. Israel DJ and Pozos RS. Synchronized slow-amplitude modulations in the electromyograms of shivering muscles. J Appl Physiol 66: 2358-2363, 1989. (Pubitemid 19142392)
16. Jeukendrup AE. Regulation of fat metabolism in skeletal muscle. Ann NY Acad Sci 967: 217-235, 2002. (Pubitemid 34721908)
17. Kosaka M and Simon E. [Central nervous spinal mechanism of cold shivering]. Pflügers Arch 302: 357-373, 1968.
18. MacNaughton K, Sathasivam. P, Vallerand A, and Graham T. Influence of caffeine on metabolic responses of men at rest in 28 and 5°C. J Appl Physiol 68: 1889-1895, 1990. (Pubitemid 20183073)
19. Martin S and Cooper KE. Factors which affect shivering in man during cold water immersion. Pflügers Arch 391: 81-83, 1981.
20. Martineau L and Jacobs I. Effects of muscle glycogen and plasma FFA availability on human metabolism responses in cold water. J Appl Physiol 71: 1331-1339, 1991.
21. Martineau L and Jacobs I. Muscle glycogen availability and temperature regulation in humans. J Appl Physiol 66: 72-78, 1989. (Pubitemid 19056060)
22. Martineau L and Jacobs I. Muscle glycogen utilization during shivering thermogenesis in humans. J Appl Physiol 65: 2046-2050, 1988. (Pubitemid 19012307)
23. Meigal A. Gross and fine neuromuscular performance at cold shivering. Int J Circumpolar Health 61: 163-172, 2002.
24. Passias TC, Meneilly GS, and Mekjavic IB. Effect of hypoglycemia on thermoregulatory responses. J Appl Physiol 80: 1021-1032, 1996. (Pubitemid 26087271)
25. Péronnet F and Massicotte D. Table of nonprotein respiratory quotient: an update. Can J Sport Sci 16: 23-29, 1991.
26. Pettit SE, Marchand I, and Graham T. Gender differences in cardiovascular and catecholamine responses to cold-air exposure at rest. Can J Appl Physiol 24: 131-147, 1999.
27. Scott CG, Ducharme MB, Haman F, and Kenny GP. Warming by immersion or exercise affects initial cooling rate during subsequent cold water immersion. Aviat Space Environ Med 75: 956-963, 2004. (Pubitemid 39435186)
28. Simon E, Klussmann FW, Rautenberg W, and Kosaka M. [Shivering from cold in anesthetized spinal dogs]. Pflügers Arch 291: 187-204, 1966.
29. Spriet LL. Regulation of skeletal muscle fat oxidation during exercise in humans. Med Sci Sports Exerc 34: 1477-1484, 2002. (Pubitemid 35006821)
30. Tikuisis P, Eyolfson DA, Xu X, and Giesbrecht GG. Shivering endurance and fatigue during cold water immersion in humans. Eur J Appl Physiol 87: 50-58, 2002. (Pubitemid 41399031)
31. Tikuisis P and Giesbrecht GG. Prediction of shivering heat production from core and mean skin temperatures. Eur J Appl Physiol 79: 221-229, 1999. (Pubitemid 29057266)
32. Tikuisis P, Jacobs I, Moroz D, Vallerand AL, and Martineau L. Comparison of thermoregulatory responses between men and women immersed in cold water. J Appl Physiol 89: 1403-1411, 2000.
33. Vallerand A, Zamenik J, and Jacobs I. Plasma glucose turnover during cold stress in humans. J Appl Physiol 78: 1296-1302, 1995.
34. Vallerand AL and Jacobs I. Influence of cold exposure on plasma triglyceride clearance in humans. Metabolism 39: 1211-1218, 1990. (Pubitemid 20376355)
35. Vallerand AL and Jacobs I. Rates of energy substrate utilization during human cold exposure. Eur J Appl Physiol 58: 873-878, 1989. (Pubitemid 19179075)
36. Vallerand AL, Jacobs I, and Kavanagh MF. Mechanism of enhanced cold tolerance by an ephedrine-caffeine mixture in humans. J Appl Physiol 67: 438-444, 1989. (Pubitemid 19196502)
37. Vallerand AL, Tikuisis P, Ducharme MB, and Jacobs I. Is energy substrate mobilization a limiting factor for cold thermogenesis? Eur J Appl Physiol 67: 239-244, 1993. (Pubitemid 23272221)
38. Vallerand AL, Zamenick J, Jones PJH, and Jacobs I. Cold stress increases lipolysis, FFA Ra and TG/FFA cycling in humans. Aviat Space Environ Med 70, 1999.
39. Weber JM and Haman F. Oxidative fuel selection: adjusting mix and flux to stay alive. In: Animals and Environments, edited by Morris S and Vosloo A. New York: Elsevier, 2004, p. 22-31. (Pubitemid 44360437)
40. Weber JM and Haman F. Fuel selection in shivering humans. Acta Physiol Scand 184: 319-329, 2005. (Pubitemid 41039737)
41. Weller AS, Greenhaff PL, and Macdonald IA. Physiological responses to moderate cold stress in man and the influence of prior prolonged exhaustive exercise. Exp Physiol 83: 679-695, 1998. (Pubitemid 28458399)
42. Xu X, Tikuisis P, Gonzalez R, and Giesbrecht G. Thermoregulatory model for prediction of long-term cold exposure. Comput Biol Med 35: 287-298, 2005. (Pubitemid 40313541)
43. Young AJ, Sawka MN, Neufer PD, Muza SR, Askew EW, and Pandolf KB. Thermoregulation during cold water immersion is impaired by low glycogen levels. J Appl Physiol 66: 1806-1816, 1989.