Switching between methadone and morphine for maintenance treatment of opioid dependence: Impact on pain sensitivity and mood status

American Journal on Addictions

Volumn 15, Issue 4, 2006, Pages 311-315

  Mitchell, Timothy ^a   White, Jason ^b,c   Somogyi, Andrew ^b,d   Bochner, Felix ^b,d  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c Drug & Alcohol Services South Australia   (Australia)

^d ROYAL ADELAIDE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

METHADONE; MORPHINE; OPIATE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG WITHDRAWAL; FEMALE; HUMAN; HYPERALGESIA; MAINTENANCE THERAPY; MALE; MOOD; MOOD DISORDER; NARCOTIC DEPENDENCE; NOCICEPTION; OPEN STUDY; PAIN; SLOW RELEASE FORMULATION;

ADULT; AFFECT; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; METHADONE; MIDDLE AGED; MORPHINE; NARCOTICS; OPIOID-RELATED DISORDERS; PAIN THRESHOLD; RETREATMENT; SUBSTANCE ABUSE DETECTION; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 33746826066     PISSN: 10550496     EISSN: 15210391     Source Type: Journal    
DOI: 10.1080/10550490600754374     Document Type: Article

References (25)

1. Williams JT, Christie MJ, Mazoni O. Cellular and synaptic adaptations mediating opioid dependence. Physiol Rev. 2001;81:299-343.
2. White JM. Pleasure into pain: the consequences of long-term opioid use. Addict Behav. 2004;29:1311-1324.
3. Compton MA. Cold-pressor pain tolerance in opiate and cocaine abusers: correlates of drug type and use status. J Pain Symptom Manage. 1994;9:462-473.
4. Compton P, Charuvastra VC, Kintaudi K, Ling W. Pain responses in methadone-maintained opioid abusers. J Pain Symptom Manage. 2000;20:237-245.
5. Compton P, Charuvastra VC, Ling W. Pain intolerance in opioid-maintained former opiate addicts: effect of long-acting maintenance agent. Drug Alcohol Depend. 2001;63:139-146.
6. Ho A, Dole VP. Pain perception in drug-free and in methadone-maintained human ex-addicts. Proceedings of the Society for Experimental Biology and Medicine. 1979;162:392-395.
7. Martin JE, Inglis J. Pain tolerance and narcotic addiction. British Journal of Social and Clinical Psychology. 1965;4:224-229.
8. Dyer KR, White JM, Foster DJ, Bochner F, Menelaou A, Somogyi AA. The relationship between mood state and plasma methadone concentration in maintenance patients. Journal Clin Psychopharmacol. 2001;21:78-84.
9. Ripamonti C, Groff L, Brunelli C, Polastri D, Stavrakis A, De Conno F. Switching from morphine to oral methadone in treating cancer pain: what is the equianalgesic dose ratio? J Clin Oncol. 1998;16:3216-3221.
10. Levy MH. Pharmacologic treatment of cancer pain. N Engl J Med. 1996;335:1124-1132.
11. Fischer G, Presslich O, Diamant K, Schneider C, Pezawas L, Kasper S. Oral morphine-sulphate in the treatment of opiate-dependent patients. Alcoholism. 1996;32:35-43.
12. Ling W, Rawson RA, Compton MA. Substitution pharmacotherapies for opioid addiction: from methadone to LAAM and buprenorphine. J Psychoactive Drugs. 1994;26:119-128.
13. Perneger TV, Giner F, Del Rio M, Mino A. (1998). Randomised trial of heroin maintenance programme for addicts who fail in conventional drug treatments. BMJ. 1998;317:13-18.
14. Mitchell TB, White JM, Somogyi AA, Bochner F. Slow-release oral morphine versus methadone: a crossover comparison of patient outcomes and acceptability as maintenance pharmacotherapies for opioid dependence. Addiction. 2004;99:940-945.
15. Mitchell TB, White JM, Somogyi AA, Bochner F. Comparative pharmacodynamics and pharmacokinetics of methadone and slow-release oral morphine for maintenance treatment of opioid dependence. Drug Alcohol Dependence. 2003;72:85-94.
16. Gossop M. The development of a Short Opiate Withdrawal Scale (SOWS). Addict Behav. 1990;15:487-490.
17. Dyer KR, Foster DJ, White JM, Somogyi AA, Menelaou A, Bochner F. Steady-state pharmacokinetics and pharmacodynamics in methadone maintenance patients: comparison of those who do and do not experience withdrawal and concentration-effect relationships. Clin Pharmacol Ther. 1999;65:685-694.
18. Doverty M, Somogyi AA, White JM, et al. Methadone maintenance patients are cross-tolerant to the antinociceptive effects of morphine. Pain. 2001;93:155-163.
19. Doverty M, White JM, Somogyi AA, Bochner F, Ali R, Ling W. Hyperalgesic responses in methadone maintenance patients. Pain. 2001;90:91-96.
20. McNair D, Lorr M, Droppleman L. EITS Manual for the Profile of Mood States. San Diego: Educational and Industrial Testing Service; 1971.
21. Haertzen CA, Hickey JE. Addiction Research Center Inventory (ARCI): Measurement of euphoria and other drug effects. In: Bozarth MA, ed. Methods of Assessing the Reinforcing Properties of Abuse Drugs. New York: Springer-Verlag;1987:489-524.
22. Dyer KR, White JM. Patterns of symptom complaints in methadone maintenance patients. Addiction. 1997;92:1445-1455.
23. Laulin JP, Celerier E, Larcher A, Le Moal M, Simonnet G. Opiate tolerance to daily heroin administration: an apparent phenomenon associated with enhanced pain sensitivity. Neuroscience. 1999;89:631-636.
24. Gorman AL, Elliott KJ, Inturrisi CE. The d- and l-isomers of methadone bind to the non-competitive site on the N-methyl-D-aspartate (NMDA) receptor in rat forebrain and spinal cord. Neurosci Lett. 1997;223:5-8.
25. Ibuki T, Dunbar SA, Yaksh TL. Effect of transient naloxone antagonism on tolerance development in rats receiving continuous spinal morphine infusion. Pain. 1997;70:125-132.