The effect of PEG concentration on the release rate of cisplatin from PEG-modified silica xerogels

Drug Delivery

Volumn 13, Issue 5, 2006, Pages 339-344

  Czarnobaj, Katarzyna ^a   Prokopowicz, Magdalena ^a   Łukasiak, Jerzy ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Cisplatin; Controlled Release; Polyethylene Glycol; Silica Xerogels; Sol Gel Method

Indexed keywords

CISPLATIN; MACROGOL; SILICON DIOXIDE;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED DRUG RELEASE; PRIORITY JOURNAL; TEMPERATURE;

ANTINEOPLASTIC AGENTS; CISPLATIN; DELAYED-ACTION PREPARATIONS; GELS; POLYETHYLENE GLYCOLS; SILANES; SILICON DIOXIDE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; TIME FACTORS;

EID: 33746809462     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.1080/10717540500394752     Document Type: Article

References (10)

1. Ahola M., Kortesuo P., Kangasniemi I., et al. 2000. Silica xerogel carrier material for controlled release of toremifene citrate. Int. J. Pharm. 195:219-227.
2. Buckley, A. M., and Greenblatt, M. 1994. The sol-gel preparation of silica gels. J. Chem. Ed. 71:599-602.
3. Czarnobaj, K., and Łukasiak, J. 2004. In vitro release of cisplatin from sol-gel processed porous silica xerogels. Drug De. 11:341-344.
4. Livage, J., and Sanchez, C. 1994. Sol-gel chemistry. J. Non-Cryst. Solids 45:11-19.
5. 2 system. J. Mol. Struct. 511-512:223-231.
6. Łukasiak, J., and Czarnobaj, K. 2002. Evaluation of the usefulness of the spectrophotometric method based on the reaction of formation of silic-molybdenic blue for determination of silica in hydrogenated fat. Roczn. PZH 53:259-265.
7. Nguyen D. T., Smit M., Dunn B., and Zink J. I. 2002. Stabilization of creatine kinase encapsulated in silicate sol-gel materials and unusual temperature effects on its activity. Chem. Mater. 14:4300-4306.
8. Radin S., Falaize S., Lee M. H., and Ducheyne P. 2002. In vitro bioactivity and degradation behavior of silica xerogels intended as controlled release materials. Biomaterials 23:3113-3122.
9. Sato, S., Murakata, T., Suzuki, T., and Ohgawara, T. 1990. Control of pore size distribution of silica gel through sol-gel process using water soluble polymers as additives. J. Mater. Sci. 254:4880-4885.
10. Schmidt, H. 1988. Chemistry of material preparation by the sol-gel process. J. Non-Cryst. Solids 100:51-64.