Synthesis of 2-bromomethyl-3-hydroxy-2-hydroxymethyl-propyl pyrimidine and theophylline nucleosides under microwave irradiation. Evaluation of their activity against hepatitis B virus

Nucleosides, Nucleotides and Nucleic Acids

Volumn 25, Issue 8, 2006, Pages 925-939

  Ashry, E S H ^a,b   Rashed, N ^a   Abdel Rahman, A ^a   Awad, L ^a   Rasheed, H ^a  

^a Alexandria University Faculty Of Science   (Egypt)

^b UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

Acyclonucleosides; Double headed acyclonucleosides; Hepatitis B virus; Micro wave alkylation reactions; Theophylline

Indexed keywords

1 [(2 BROMOMETHYL 3 HYDROXY 2 HYDROXYMETHYL)PROP 1 YL] 2 METHYLTHIO 6 PROPYLPYRIMIDIN 4(1H) ONE; 1 [(2 BROMOMETHYL 3 HYDROXY 2 HYDROXYMETHYL)PROP 1 YL] 2 METHYLTHIOPYRIMIDIN 4(1H) ONE; 1 [(2 BROMOMETHYL 3 HYDROXY 2 HYDROXYMETHYL)PROP 1 YL] 5 METHYL 2 METHYLTHIOPYRIMIDIN 4(1H) ONE; 1 [(2 BROMOMETHYL 3 HYDROXY 2 HYDROXYMETHYL)PROP 1 YL] 6 METHYL 2 METHYLTHIOPYRIMIDIN 4(1H) ONE; 1 [(3 ACETOXY 2 ACETOXYMETHYL 2 BROMOMETHYL)PROP 1 YL] 2 METHYLTHIO 6 N PROPYLPYRIMIDIN 4(1H) ONE; 1 [(3 ACETOXY 2 ACETOXYMETHYL 2 BROMOMETHYL)PROP 1 YL] 2 METHYLTHIOPYRIMIDIN 4(1H) ONE; 1 [(3 ACETOXY 2 ACETOXYMETHYL 2 BROMOMETHYL)PROP 1 YL] 5 METHYL 2 METHYLTHIOPYRIMIDIN 4(1H) ONE; 1 [(3 ACETOXY 2 ACETOXYMETHYL 2 BROMOMETHYL)PROP 1 YL] 6 METHYL 2 METHYLTHIOPYRIMIDIN 4(1H) ONE; 1,1' [(2,2 DIACETOXYMETHYL) 1,3 PROPYLIDENE]BIS[(2 METHYLTHIO)PYRIMIDIN 4(1H) ONE]; 1,1' [(2,2 DIACETOXYMETHYL) 1,3 PROPYLIDENE]BIS[5 METHYL 2 (METHYLTHIO)PYRIMIDIN 4(1H) ONE]; 1,1' [(2,2 DIACETOXYMETHYL) 1,3 PROPYLIDENE]BIS[6 METHYL 2 (METHYLTHIO)PYRIMIDIN 4(1H) ONE]; 7 [(3 ACETOXY 2 ACETOXYMETHYL 2 BROMOMETHYL)PROP 1 YL]THEOPHYLLINE; 7,7' [(2,2 DIACETOXYMETHYL) 1,3 PROPYLIDENE]BIS(THEOPHYLLINE); ACYCLIC NUCLEOSIDE; ANTIVIRUS AGENT; LAMIVUDINE; UNCLASSIFIED DRUG;

ALKYLATION; ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DEACETYLATION; DRUG SYNTHESIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IC 50; MICROWAVE IRRADIATION; NONHUMAN; POLYMERASE CHAIN REACTION;

ANTIVIRAL AGENTS; CELLS, CULTURED; HEPATITIS B VIRUS; HUMANS; MICROWAVES; PYRIMIDINE NUCLEOSIDES; PYRIMIDINONES; THEOPHYLLINE;

HEPATITIS B VIRUS;

EID: 33746791543     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770600793919     Document Type: Article

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