Simple synthesis of a building block for solid-phase labeling of oligonucleotides with 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)

Bioconjugate Chemistry

Volumn 17, Issue 4, 2006, Pages 1105-1107

  Jaakkola, Lassi ^a   Ylikoski, Alice ^a   Hovinen, Jari ^a  

^a PerkinElmer Finland Oy   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

SYNTHESIS (CHEMICAL);

BUILDING BLOCKES; LABELINGS; PHOSPHORAMIDITES; SIMPLE++; SOLID PHASIS; SOLID-PHASE; TETRAACETIC ACID;

OLIGONUCLEOTIDES;

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; OLIGONUCLEOTIDE;

ARTICLE; CONJUGATION; PURIFICATION; REACTION ANALYSIS; SOLID; SYNTHESIS;

EID: 33746779416     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0600362     Document Type: Article

References (12)

1. Aime, S., Botta, M., Fasano, M., and Terreno, E. (1998) Lanthanide-(III) chelates for NMR biomedical applications. Chem. Soc. Rev. 27, 19-29.
2. Caravan, P., Ellison, J. J., McMurry, T. J., and Lauffer, R. B. (1999) Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications. Chem. Rev. 99, 2293-2352.
3. Woods, M., Kovacs, Z., and Sherry, A. D. (2002) Targeted complexes of lanthanide(III) ions as therapeutic and diagnostic pharmaceuticals. J. Supramol. Chem. 2, 1-15.
4. Runge, V. M. (2000) Safety of approved MR contrast media for intravenous injection. J. Magn. Reson Imaging 12, 205-213.
5. Anderson, C. J., and Welch, M. J. (1999) Radiometal-labeled agents (non-technetium) for diagnostic imaging. Chem. Rev. 99, 2219-2234.
6. Volkert, W. A., and Hoffman, T. J. (1999) Therapeutic radiopharmaceuticals. Chem. Rev. 99, 2269-2292.
7. Fichna, J., and Janecka, A. (2003) Synthesis of target-specific radiolabeled peptides for diagnostic imaging. Bioconjugate Chem. 14, 3-17.
8. Heppeler, A., Froilevaux, S., Mäcke, H. R., Jermann, H. E., Béhé, M., Powell, P., and Hennig, M. (1999) Radiometal-labeled macrocyclic chelator-derivatised somatostatin analogue with superb tumor-targeting properties and potential for receptor-mediated tumor therapy. Chem. Eur. J. 1, 1974-1981.
9. De Leon-Rodriguez, Kovacs, Z., Dieckmann, G. R., Sherry, A. D. (2004) Solid-phase synthesis of DOTA-peptides. Chem. Eur. J. 10, 1149-1155.
10. 68Ga-labelling of oligonucleotides. J. Labelled Compd. Radiopharm. 47, 79-89.
11. 68Ga-labelled oligonucleotides for in vivo imaging with PET. J. Nucl. Med. 45, 347-355.
12. Hakala, H., and Hovinen, J. (2001) Versatile strategy for oligonucleotide derivatization. Introduction of lanthanide(III) chelates to oligonucleotides. Org. Lett. 3, 2473-2476