In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 69, Issue 15, 2006, Pages 1431-1440

  Kuca, Kamil ^a   Cabal, Jiri ^a   Kassa, Jiri ^a,b   Jun, Daniel ^a   Hrabinova, Martina ^a  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b UNIVERSITY OF DEFENCE   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ACETYLCHOLINESTERASE; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; OBIDOXIME; OXIME BI 6; OXIME DERIVATIVE; PRALIDOXIME; TABUN; TRIMEDOXIME; UNCLASSIFIED DRUG; 1 (4 CARBAMOYLPYRIDINIO) 4 (2 HYDROXYIMINOMETHYLPYRIDINIO) 2 BUTENE DIBROMIDE; 1 [2,4 BIS(HYDROXYIMINOMETHYL)PYRIDINIO] 1' (4 CARBAMOYLPYRIDINIO)DIMETHYL ETHER DIIODIDE; ANTIDOTE; CHEMICAL WARFARE AGENT; CHOLINESTERASE INHIBITOR; CHOLINESTERASE REACTIVATOR; ORGANOPHOSPHATE; OXIME; PHOSPHOROTHIOIC ACID DERIVATIVE; PYRIDINE DERIVATIVE; PYRIDINIUM DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN CELL; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG POTENCY; ENZYME INHIBITION; ENZYME REACTIVATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BRAIN; DRUG EFFECT; PHYSIOLOGY; WISTAR RAT;

ACETYLCHOLINESTERASE; ANIMALS; ANTIDOTES; BRAIN; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; MALE; OBIDOXIME CHLORIDE; ORGANOTHIOPHOSPHORUS COMPOUNDS; OXIMES; PHOSPHORIC ACID ESTERS; PRALIDOXIME COMPOUNDS; PYRIDINES; PYRIDINIUM COMPOUNDS; RATS; RATS, WISTAR; TRIMEDOXIME;

EID: 33746756763     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390500364283     Document Type: Article

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