Atypical warfarin-induced skin necrosis

Pharmacotherapy

Volumn 26, Issue 8 I, 2006, Pages 1175-1179

  Ward, Ceressa T ^a,b   Chavalitanonda, Nann ^b  

^a NOVA SOUTHEASTERN UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Anticoagulation; Skin necrosis; Warfarin

Indexed keywords

ACETYLSALICYLIC ACID; BACITRACIN; DEXTROMETHORPHAN; DIPHENHYDRAMINE; FLUOCINONIDE; GLYCERYL TRINITRATE; GUAIFENESIN; IBUPROFEN; IPRATROPIUM BROMIDE; METHYLPREDNISOLONE; OXYBUTYNIN; PAROXETINE; PREDNISONE; RANITIDINE; SALBUTAMOL; TEMAZEPAM; WARFARIN;

ADULT; ARTICLE; CASE REPORT; CAUCASIAN; DISEASE ASSOCIATION; DRUG EXPOSURE; DRUG HYPERSENSITIVITY; EVALUATION; FEMALE; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LEUKOCYTOCLASTIC VASCULITIS; OBESITY; PATHOGENESIS; RATING SCALE; SKIN BIOPSY; SKIN MANIFESTATION; SKIN NECROSIS; THROMBOEMBOLISM;

ADULT; ANTICOAGULANTS; FATAL OUTCOME; FEMALE; HUMANS; NECROSIS; SKIN; SKIN DISEASES; WARFARIN;

EID: 33746754745     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.26.8.1175     Document Type: Article

References (23)

1. Last JA. The missing link: the story of Karl Paul Link. Toxicol Sci 2002;66:4-6.
2. Ansell J, Hirsh J, Poller L, Bussey H, Jacobson A, Hylek E. The pharmacology and management of the vitamin K antagonists. Chest 2004;126(suppl):204S-33.
3. Goldberg SL, Orthner CL, Yalisove BL, Elgart ML, Kessler CM. Skin necrosis following prolonged administration of coumarin in a patient with inherited protein S deficiency. Am J Hematol 1991;38:64-6.
4. Gelwix TJ, Beeson MS. Warfarin-induced skin necrosis. Am J Emerg Med 1998;16:541-3.
5. Valdivielso M, Longo I, Lecona M, Lázaro P. Cutaneous necrosis induced by acenocoumarol. J Eur Acad Dermatol Venereol 2004;18:211-15.
6. Chan YC, Valenti D, Mansfield AO, Stansby G. Warfarin induced skin necrosis. Br J Surg 2000;87:266-72.
7. Eby CS. Warfarin-induced skin necrosis. Hematol Oncol Clin North Am 1993;7:1291-300.
8. Sternberg ML, Pettyjohn FS. Warfarin sodium-induced skin necrosis. Ann Emerg Med 1995;26:94-7.
9. Hyers TM, Agnelli G, Hull RD, et al. Antithrombotic therapy for venous thromboembolic disease. Chest 1998;114(suppl 5):561S-78.
10. Grimaudo V, Gueissaz F, Hauert J, Sarraj A, Kruithof EKO, Bachman F. Necrosis of skin induced by coumarin in a patient deficient in protein S. BMJ 1989;298:233-4.
11. Harrison L, Johnston M, Massicotte MP, Crowther M, Moffat K, Hirsh J. Comparison of 5-mg and 10-mg loading doses in initiation of warfarin therapy. Ann Intern Med 1997;126:133-6.
12. Gailani D, Reese EP. Anticoagulant-induced skin necrosis in a patient with hereditary deficiency of protein S. Am J Hematol 1999;60:231-6.
13. Majerus PW, Broze GJ, Miletich JP, Tollefsen DM. Anticoagulant, thrombolytic, and antiplatelet drugs. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Goodman LS, Gilman A, eds. Goodman & Gilman's the pharmacological basis of therapeutics. New York: McGraw-Hill, 1996:1341-59.
14. Esmon CT. Regulatory mechanisms in hemostasis: natural anticoagulants. In: Hoffman R, Benz EJ, Shattil SJ, et al, eds. Hematology: basic principles and practice. Philadelphia: Churchill Livingstone, 2005:1963-8.
15. Nalbandian RM, Mader IJ, Barrett JL, Pearce JF, Rupp EC. Petechiae, ecchymoses, and necrosis of skin induced by coumarin congeners. JAMA 1965;192:107-12.
16. Chosidow OM, Stern RS, Wintroub BU. Cutaneous drug reactions. In: Kasper DL, Braunwald E, Fauci AS, et al, eds. Harrison's principles of internal medicine. New York: McGraw-Hill, 2005:318-24.
17. Scarff CE, Baker C, Hill P, Foley P. Late-onset warfarin necrosis. Australas J Dermatol 2002;45:202-6.
18. Essex DW, Wynn SS, Jin DK. Late-onset warfarin-induced skin necrosis: case report and review of the literature. Am J Hematol 1998;57:233-7.
19. Alves DW, Chen IA. Warfarin-induced skin necrosis. Hosp Phys 2002;38:39-42.
20. Beitz JM. Coumadin-induced skin necrosis. Wounds 2002;14:217-20.
21. Jiménez-Gonzalo FJ, Medina-Pérez M, Marín- Martín J. Acenocoumarol-induced leukocytoclastic vasculitis. Haematologica 1999;84:462-3.
22. Jillella AP, Lutcher CL. Reinstituting warfarin in patients who develop warfarin skin necrosis. Am J Hematol 1996;52:117-19.
23. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.