Nε-(3[*I]iodobenzoyl)-Lys5-N α-maleimido-Gly1-GEEEK([*I]IB-Mal-D-GEEEK): A radioiodinated prosthetic group containing negatively charged D-glutamates for labeling internalizing monoclonal antibodies

Bioconjugate Chemistry

Volumn 17, Issue 4, 2006, Pages 1085-1092

  Vaidyanathan, Ganesan ^a   Alston, Kevin L ^a   Bigner, Darrel D ^a   Zalutsky, Michael R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; RADIATION; RADIOACTIVITY; TUMORS;

D-AMINO ACIDS; EPIDERMAL GROWTH FACTOR RECEPTORS; LABELINGS; LABELLED PROTEIN; NEGATIVELY CHARGED; NOVEL METHODS; PROSTHETIC GROUPS; RADIOCHEMICAL YIELD; RADIOIODINATION; SYNTHESISED;

MONOCLONAL ANTIBODIES;

DEXTRO GLUTAMIC ACID; EPIDERMAL GROWTH FACTOR RECEPTOR 3; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY L8A4; NEPSILON (3 IODOBENZOYL)LYSINE 5N ALPHA MALEIMIDOGLYCINE I 125; RADIOACTIVE IODINE; UNCLASSIFIED DRUG; GLUTAMIC ACID; IODOBENZENE; OLIGOPEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLIOMA CELL; MOUSE; NONHUMAN; NUDE MOUSE; PROTEIN DEGRADATION; RADIOCHEMISTRY; RADIOIODINATION; XENOGRAFT; ANIMAL; BRAIN TUMOR; CHEMISTRY; GLIOMA; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; BRAIN NEOPLASMS; CELL LINE, TUMOR; GLIOMA; GLUTAMIC ACID; IODINE RADIOISOTOPES; IODOBENZENES; MICE; OLIGOPEPTIDES; TISSUE DISTRIBUTION;

EID: 33746747057     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0600766     Document Type: Article

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