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Volumn 47, Issue 7, 2006, Pages 2847-2856

Apical corneal barrier disruption in experimental murine dry eye is abrogated by methylprednisolone and doxycycline

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; INVOLUCRIN; METHYLPREDNISOLONE; ANTIINFLAMMATORY AGENT; MEMBRANE PROTEIN; MESSENGER RNA; OCCLUDIN; OREGON GREEN BAPTA DEXTRAN; OREGON GREEN BAPTA-DEXTRAN; ORGANIC COMPOUND; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN PRECURSOR; SPRR2A PROTEIN, MOUSE; TRANSGLUTAMINASE 1;

EID: 33746713884     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-1281     Document Type: Article
Times cited : (150)

References (40)
  • 1
    • 0025374184 scopus 로고
    • Keratoconjunctivitis sicca and corneal ulcers
    • Hemady R, Chu W, Foster CS. Keratoconjunctivitis sicca and corneal ulcers. Cornea. 1990;9:170-173.
    • (1990) Cornea , vol.9 , pp. 170-173
    • Hemady, R.1    Chu, W.2    Foster, C.S.3
  • 3
    • 0020552796 scopus 로고
    • Demographic and predisposing factors in corneal ulceration
    • Musch DC, Sugar A, Meyer RF. Demographic and predisposing factors in corneal ulceration. Arch Ophthalmol. 1983;101:1545-1548.
    • (1983) Arch Ophthalmol , vol.101 , pp. 1545-1548
    • Musch, D.C.1    Sugar, A.2    Meyer, R.F.3
  • 4
    • 0025161590 scopus 로고
    • A new perspective on canine keratoconjunctivitis sicca: Treatment with ophthalmic cyclosporine
    • Kaswan RL, Salisbury MA. A new perspective on canine keratoconjunctivitis sicca: treatment with ophthalmic cyclosporine. Vet Clin North Am Small Anim Pract. 1990;20:583-613.
    • (1990) Vet Clin North Am Small Anim Pract , vol.20 , pp. 583-613
    • Kaswan, R.L.1    Salisbury, M.A.2
  • 5
    • 0025396044 scopus 로고
    • Dry eye syndrome in a Pakistani community
    • Jehangir S. Dry eye syndrome in a Pakistani community. J Pak Med Assoc. 1990;40:66-67.
    • (1990) J Pak Med Assoc , vol.40 , pp. 66-67
    • Jehangir, S.1
  • 6
    • 0028790898 scopus 로고
    • Simultaneous evaluation of tear turnover and corneal epithelial permeability by fluorophotometry in normal subjects and patients with keratoconjunctivitis sicca (KCS)
    • Nelson JD. Simultaneous evaluation of tear turnover and corneal epithelial permeability by fluorophotometry in normal subjects and patients with keratoconjunctivitis sicca (KCS). Trans Am Ophthalmol Soc. 1995;93:709-753.
    • (1995) Trans Am Ophthalmol Soc , vol.93 , pp. 709-753
    • Nelson, J.D.1
  • 7
    • 0026557768 scopus 로고
    • Comparison of fluorescein and rose bengal staining
    • Feenstra RPG, Tseng SCG. Comparison of fluorescein and rose bengal staining. Ophthalmology. 1992;99:605-617.
    • (1992) Ophthalmology , vol.99 , pp. 605-617
    • Feenstra, R.P.G.1    Tseng, S.C.G.2
  • 8
    • 0029164337 scopus 로고
    • Clinical evaluation of corneal epithelial barrier function with the slit-lamp fluorophotometer
    • Yokoi N, Kinoshita S. Clinical evaluation of corneal epithelial barrier function with the slit-lamp fluorophotometer. Cornea. 1995;14:485-489.
    • (1995) Cornea , vol.14 , pp. 485-489
    • Yokoi, N.1    Kinoshita, S.2
  • 9
    • 0025835075 scopus 로고
    • Effects of artificial tears on corneal epithelial permeability in dry eyes
    • Gobbels M, Spitznas M. Effects of artificial tears on corneal epithelial permeability in dry eyes. Graefes Arch Clin Exp Ophthalmol. 1991;229:345-349.
    • (1991) Graefes Arch Clin Exp Ophthalmol , vol.229 , pp. 345-349
    • Gobbels, M.1    Spitznas, M.2
  • 10
    • 0026776309 scopus 로고
    • Corneal epithelial permeability of dry eyes before and after treatment with artificial tears
    • Gobbels M, Spitznas M. Corneal epithelial permeability of dry eyes before and after treatment with artificial tears. Ophthalmology. 1992;99:873-878.
    • (1992) Ophthalmology , vol.99 , pp. 873-878
    • Gobbels, M.1    Spitznas, M.2
  • 11
    • 0031984088 scopus 로고    scopus 로고
    • Evaluation of subjective assessments and objective diagnostic tests for diagnosing tearfilm disorders known to cause ocular irritation
    • Pflugfelder SC, Tseng SCG, Sanabria O, et al. Evaluation of subjective assessments and objective diagnostic tests for diagnosing tearfilm disorders known to cause ocular irritation. Cornea. 1998;17:38-56.
    • (1998) Cornea , vol.17 , pp. 38-56
    • Pflugfelder, S.C.1    Tseng, S.C.G.2    Sanabria, O.3
  • 12
    • 0031801926 scopus 로고    scopus 로고
    • Low spatial-contrast sensitivity in dry eyes
    • Rolando M, Iester M, Macri A, Calabria G. Low spatial-contrast sensitivity in dry eyes. Cornea. 1998;17:376-379.
    • (1998) Cornea , vol.17 , pp. 376-379
    • Rolando, M.1    Iester, M.2    Macri, A.3    Calabria, G.4
  • 13
    • 0034105080 scopus 로고    scopus 로고
    • Two multicenter, randomized studies of the efficacy and safety of cyclosporine ophthalmic emulsion in moderate to severe dry eye disease. CsA Phase 3 Study Group
    • Sall K, Stevenson OD, Mundorf TK, Reis BL. Two multicenter, randomized studies of the efficacy and safety of cyclosporine ophthalmic emulsion in moderate to severe dry eye disease. CsA Phase 3 Study Group. Ophthalmology. 2000;107:631-639.
    • (2000) Ophthalmology , vol.107 , pp. 631-639
    • Sall, K.1    Stevenson, O.D.2    Mundorf, T.K.3    Reis, B.L.4
  • 14
    • 1242316166 scopus 로고    scopus 로고
    • Anti-inflammatory therapy of dry eye
    • Pflugfelder SC. Anti-inflammatory therapy of dry eye. Am J Ophthalmol. 2004;137:337-342.
    • (2004) Am J Ophthalmol , vol.137 , pp. 337-342
    • Pflugfelder, S.C.1
  • 15
    • 4444368235 scopus 로고    scopus 로고
    • A randomized, double-masked, placebo-controlled, multicenter comparison of loteprednol etabonate ophthalmic suspension, 0.5%, and placebo for treatment of keratoconjunctivitis sicca in patients with delayed tear clearance
    • Pflugfelder SC, Maskin SL, Anderson B, et al. A randomized, double-masked, placebo-controlled, multicenter comparison of loteprednol etabonate ophthalmic suspension, 0.5%, and placebo for treatment of keratoconjunctivitis sicca in patients with delayed tear clearance. Am J Ophthalmol. 2004;138:444-457.
    • (2004) Am J Ophthalmol , vol.138 , pp. 444-457
    • Pflugfelder, S.C.1    Maskin, S.L.2    Anderson, B.3
  • 16
    • 11144221616 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye
    • Pflugfelder SC, Farley W, Luo L, et al. Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye. Am J Pathol. 2005;166:61-71.
    • (2005) Am J Pathol , vol.166 , pp. 61-71
    • Pflugfelder, S.C.1    Farley, W.2    Luo, L.3
  • 18
    • 12144274468 scopus 로고    scopus 로고
    • ABCG2 transporter identifies a population of clonogenic human limbal epithelial cells
    • de Paiva CS, Chen Z, Corrales RM, Pflugfelder SC, Li DQ. ABCG2 transporter identifies a population of clonogenic human limbal epithelial cells. Stem Cells. 2005;23:63-73.
    • (2005) Stem Cells , vol.23 , pp. 63-73
    • de Paiva, C.S.1    Chen, Z.2    Corrales, R.M.3    Pflugfelder, S.C.4    Li, D.Q.5
  • 19
    • 0346729847 scopus 로고    scopus 로고
    • Corneal epitheliopathy of dry eye induces hyperesthesia to mechanical air jet stimulation
    • de Paiva CS, Pflugfelder SC. Corneal epitheliopathy of dry eye induces hyperesthesia to mechanical air jet stimulation. Am J Ophthalmol. 2004;137:109-115.
    • (2004) Am J Ophthalmol , vol.137 , pp. 109-115
    • de Paiva, C.S.1    Pflugfelder, S.C.2
  • 21
    • 0028900002 scopus 로고
    • Three patterns of cytokine expression potentially involved in epithelial-fibroblast interactions of human ocular surface
    • Li DQ, Tseng SC. Three patterns of cytokine expression potentially involved in epithelial-fibroblast interactions of human ocular surface. J Cell Physiol. 1995;163:61-79.
    • (1995) J Cell Physiol , vol.163 , pp. 61-79
    • Li, D.Q.1    Tseng, S.C.2
  • 23
    • 9444263191 scopus 로고    scopus 로고
    • Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface
    • Luo L, Li DQ, Doshi A, Farley W, Corrales RM, Pflugfelder SC. Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface. Invest Ophthalmol Vis Sci. 2004;45:4293-4301.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 4293-4301
    • Luo, L.1    Li, D.Q.2    Doshi, A.3    Farley, W.4    Corrales, R.M.5    Pflugfelder, S.C.6
  • 24
    • 0034849206 scopus 로고    scopus 로고
    • Proand anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease
    • Solomon A, Dursun D, Liu Z, Xie Y, Macri A, Pflugfelder SC. Proand anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease. Invest Ophthalmol Vis Sci. 2001;42:2283-2292.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2283-2292
    • Solomon, A.1    Dursun, D.2    Liu, Z.3    Xie, Y.4    Macri, A.5    Pflugfelder, S.C.6
  • 25
    • 0032871943 scopus 로고    scopus 로고
    • Tear fluid gelatinase B activity correlates with IL-1alpha concentration and fluorescein clearance in ocular rosacea
    • Afonso AA, Sobrin L, Monroy DC, Selzer M, Lokeshwar B, Pflugfelder SC. Tear fluid gelatinase B activity correlates with IL-1alpha concentration and fluorescein clearance in ocular rosacea. Invest Ophthalmol Vis Sci. 1999;40:2506-2512.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2506-2512
    • Afonso, A.A.1    Sobrin, L.2    Monroy, D.C.3    Selzer, M.4    Lokeshwar, B.5    Pflugfelder, S.C.6
  • 26
    • 0004191881 scopus 로고    scopus 로고
    • Regulation of MMP-9 activity in human tear fluid and corneal epithelial culture supernatant
    • Sobrin L, Liu Z, Monroy DC, et al. Regulation of MMP-9 activity in human tear fluid and corneal epithelial culture supernatant. Invest Ophthalmol Vis Sci. 2000;41:1703-1709.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 1703-1709
    • Sobrin, L.1    Liu, Z.2    Monroy, D.C.3
  • 27
    • 0344688189 scopus 로고    scopus 로고
    • Activation of ERK1/2 MAP kinase pathway induces tight junction disruption in human corneal epithelial cells
    • Wang Y, Zhang J, Yi XJ, Yu FS. Activation of ERK1/2 MAP kinase pathway induces tight junction disruption in human corneal epithelial cells. Exp Eye Res. 2004;78:125-136.
    • (2004) Exp Eye Res , vol.78 , pp. 125-136
    • Wang, Y.1    Zhang, J.2    Yi, X.J.3    Yu, F.S.4
  • 28
    • 2142819385 scopus 로고    scopus 로고
    • Regulation of involucrin expression in normal human corneal epithelial cells: A role for activator protein one
    • Adhikary G, Crish J, Lass J, Eckert RL. Regulation of involucrin expression in normal human corneal epithelial cells: a role for activator protein one. Invest Ophthalmol Vis Sci. 2004;45:1080-1087.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1080-1087
    • Adhikary, G.1    Crish, J.2    Lass, J.3    Eckert, R.L.4
  • 29
    • 0032990608 scopus 로고    scopus 로고
    • Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes
    • Zeigler ME, Chi Y, Schmidt T, Varani J. Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes. J Cell Physiol. 1999;180:271-284.
    • (1999) J Cell Physiol , vol.180 , pp. 271-284
    • Zeigler, M.E.1    Chi, Y.2    Schmidt, T.3    Varani, J.4
  • 30
    • 0037200088 scopus 로고    scopus 로고
    • Activation of p38a MAPK enhances collagenase-1 (MMP-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization
    • Reunanen N, Li SP, Ahonen M, Foschi M, Han J, Kahari VM. Activation of p38a MAPK enhances collagenase-1 (MMP-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization. J Biol Chem. 2002;277:32360-32368.
    • (2002) J Biol Chem , vol.277 , pp. 32360-32368
    • Reunanen, N.1    Li, S.P.2    Ahonen, M.3    Foschi, M.4    Han, J.5    Kahari, V.M.6
  • 31
    • 0036252640 scopus 로고    scopus 로고
    • Inhibition of interleukin-1-stimulated MAP kinases, activating protein- 1 (AP-1) and nuclear factor kappa B (NF-kappaB) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes
    • Liacini A, Sylvester J, Li WQ, Zafarullah M. Inhibition of interleukin-1-stimulated MAP kinases, activating protein- 1 (AP-1) and nuclear factor kappa B (NF-kappaB) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes. Matrix Biol. 2002;21:251-262.
    • (2002) Matrix Biol , vol.21 , pp. 251-262
    • Liacini, A.1    Sylvester, J.2    Li, W.Q.3    Zafarullah, M.4
  • 32
    • 0035504250 scopus 로고    scopus 로고
    • IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: Requirement for Runx-2 and activation by p38 MAPK and JNK pathways
    • Mengshol JA, Vincenti MP, Brinckerhoff CE. IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways. Nucleic Acids Res. 2001;29:4361-4372.
    • (2001) Nucleic Acids Res , vol.29 , pp. 4361-4372
    • Mengshol, J.A.1    Vincenti, M.P.2    Brinckerhoff, C.E.3
  • 34
    • 5644230846 scopus 로고    scopus 로고
    • Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: Up-regulation by interleukin-1beta and glucocorticoids
    • Toh ML, Yang Y, Leech M, Santos L, Morand EF. Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids. Arthritis Rheum. 2004;50:3118-3128.
    • (2004) Arthritis Rheum , vol.50 , pp. 3118-3128
    • Toh, M.L.1    Yang, Y.2    Leech, M.3    Santos, L.4    Morand, E.F.5
  • 35
    • 0036841288 scopus 로고    scopus 로고
    • Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38
    • Lasa M, Abraham SM, Boucheron C, Saklatvala J, Clark AR. Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Mol Cell Biol. 2002;22:7802-7811.
    • (2002) Mol Cell Biol , vol.22 , pp. 7802-7811
    • Lasa, M.1    Abraham, S.M.2    Boucheron, C.3    Saklatvala, J.4    Clark, A.R.5
  • 36
    • 0037126628 scopus 로고    scopus 로고
    • Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
    • Kassel O, Sancono A, Kratzschmar J, Kreft B, Stassen M, Cato AC. Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1. EMBO J. 2001;20:7108-7116.
    • (2001) EMBO J , vol.20 , pp. 7108-7116
    • Kassel, O.1    Sancono, A.2    Kratzschmar, J.3    Kreft, B.4    Stassen, M.5    Cato, A.C.6
  • 37
    • 3242785662 scopus 로고    scopus 로고
    • Minocycline suppresses hypoxic activation of rodent microglia in culture
    • Suk K. Minocycline suppresses hypoxic activation of rodent microglia in culture. Neurosci Lett. 2004;366:167-171.
    • (2004) Neurosci Lett , vol.366 , pp. 167-171
    • Suk, K.1
  • 38
    • 9444230614 scopus 로고    scopus 로고
    • Stimulation of matrix metalloproteinases by hyperosmolarity via a JNK pathway in human corneal epithelial cells
    • Li DQ, Chen Z, Song XJ, Luo L, Pflugfelder SC. Stimulation of matrix metalloproteinases by hyperosmolarity via a JNK pathway in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2004;45:4302-4311.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 4302-4311
    • Li, D.Q.1    Chen, Z.2    Song, X.J.3    Luo, L.4    Pflugfelder, S.C.5
  • 39
    • 0037983882 scopus 로고    scopus 로고
    • Assessing the severity of keratitis sicca with videokeratoscopic indices
    • de Paiva CS, Lindsey JL, Pflugfelder SC. Assessing the severity of keratitis sicca with videokeratoscopic indices. Ophthalmology. 2003;110:1102-1109.
    • (2003) Ophthalmology , vol.110 , pp. 1102-1109
    • de Paiva, C.S.1    Lindsey, J.L.2    Pflugfelder, S.C.3
  • 40
    • 0033504461 scopus 로고    scopus 로고
    • Topical nonpreserved methylprednisolone therapy for keratoconjunctivitis sicca in Sjogren syndrome
    • Marsh P, Pflugfelder SC. Topical nonpreserved methylprednisolone therapy for keratoconjunctivitis sicca in Sjogren syndrome. Ophthalmology. 1999;106:811-816.
    • (1999) Ophthalmology , vol.106 , pp. 811-816
    • Marsh, P.1    Pflugfelder, S.C.2


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