North and South American Loxosceles spiders: Development of a polyvalent antivenom with recombinant sphingomyelinases D as antigens

Toxicon

Volumn 48, Issue 1, 2006, Pages 64-74

  Olvera, Alejandro ^a   Ramos Cerrillo, Blanca ^a   Estévez, Judith ^b   Clement, Herlinda ^a   de Roodt, Adolfo ^c   Paniagua Solís, Jorge ^b   Vázquez, Hilda ^b   Zavaleta, Alfonso ^d   Salas Arruz, María ^d   Stock, Roberto P ^a   Alagón, Alejandro ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^b Laboratorios Silanes SA de CV   (Mexico)

^c Sección Farmacología   (Peru)

^d Administracion Nacional   (Argentina)

Author keywords

Antivenom; Enzymatic activity; Loxosceles; Recombinant sphingomyelinase D

Indexed keywords

ANTIGEN; COMPLEMENTARY DNA; HISTIDINE; IMMUNOGLOBULIN F(AB')2 FRAGMENT; RABBIT ANTISERUM; RECOMBINANT ENZYME; RECOMBINANT SPHINGOMYELINASE D; SPHINGOMYELIN PHOSPHODIESTERASE; SPIDER VENOM; SPIDER VENOM ANTISERUM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; FEASIBILITY STUDY; GENE EXPRESSION SYSTEM; MOLECULAR CLONING; MOUSE; NONHUMAN; NORTH AMERICA; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; SOUTH AMERICA; SPIDER;

AMINO ACID SEQUENCE; ANIMALS; ANTIVENINS; BASE SEQUENCE; CROSS REACTIONS; IMMUNOGLOBULIN FAB FRAGMENTS; MOLECULAR SEQUENCE DATA; PHOSPHORIC DIESTER HYDROLASES; RABBITS; RECOMBINANT PROTEINS; SPIDER VENOMS;

ANIMALIA; ARANEAE; BACTERIA (MICROORGANISMS); EQUIDAE; LOXOSCELES; LOXOSCELES BONETI; LOXOSCELES LAETA; LOXOSCELES RECLUSA; ORYCTOLAGUS CUNICULUS;

EID: 33746649729     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.04.010     Document Type: Article

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