Neuregulin effect on quantal content dissociated from effect on miniature endplate potential amplitude

Journal of Neurophysiology

Volumn 96, Issue 2, 2006, Pages 671-676

  Mann, Mary Anne ^a   Das, Saumya ^b   Zhang, Jinghua ^a   Wagner, Meredith ^a   Fischbach, Gerald D ^a  

^a Columbia University ^*  (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CHOLINERGIC RECEPTOR; NEU DIFFERENTIATION FACTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISSOCIATION; HETEROZYGOSITY; MINIATURE ENDPLATE POTENTIAL; MOUSE; MUSCLE CELL; NEUROTRANSMITTER RELEASE; NONHUMAN; POSTNATAL DEVELOPMENT; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING;

ANIMALS; BUNGAROTOXINS; ELECTRIC STIMULATION; EMBRYO; EVOKED POTENTIALS, MOTOR; FEMALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ENDPLATE; MUSCLE FIBERS; NEUREGULINS; NEUROTRANSMITTER AGENTS; PREGNANCY; RNA, MESSENGER; SYNAPTIC TRANSMISSION;

EID: 33746603528     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00225.2006     Document Type: Article

References (54)

1. Altiok N, Bessereau JL, and Changeux JP. ErbB3 and ErbB2/neu mediate the effect of heregulin on acetylcholine receptor gene expression in muscle: differential expression at the endplate. EMBO J 14: 4258-4266, 1995.
2. Andrechek ER, Hardy WR, Girgis-Gabardo AA, Perry RL, Butler R, Graham FL, Kahn RC, Rudnicki MA, and Muller WJ. ErbB2 is required for muscle spindle and myoblast cell survival. Mol Cell Biol 22: 4714-4722, 2002.
3. Brenner HR, Rotzler S, Kues WA, Witzemann V, and Sakmann B. Nerve-dependent induction of AChR epsilon-subunit gene expression in muscle is independent of state of differentiation. Dev Biol 165: 527-536, 1994.
4. Buonanno A and Fischbach GD. Neuregulin and ErbB receptor signaling pathways in the nervous system. Curr Opin Neurobiol 11: 287-296, 2001.
5. Corfas G, Rosen KM, Aratake H, Krauss R, and Fischbach GD. Differential expression of ARIA isoforms in the rat brain. Neuron 14: 103-115, 1995.
6. Crawley JN, Belknap JK, Collins A, Crabbe JC, Frankel W, Henderson N, Hitzemann RJ, Maxson SC, Miner LL, Silva AJ, Wehner JM, Wynshaw-Boris A, and Paylor R. Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology 132: 107-124, 1997.
7. Cull-Candy SG, Miledi R, Trautmann A, and Uchitel OD. On the release of transmitter at normal, myasthenia gravis and myasthenic syndrome affected human end-plates. J Physiol 299: 621-638, 1980.
8. Davis GW and Bezprozvanny I. Maintaining the stability of neural function: a homeostatic hypothesis. Annu Rev Physiol 63: 847-869, 2001.
9. Davis GW, DiAntonio A, Petersen SA, and Goodman CS. Postsynaptic PKA controls quantal size and reveals a retrograde signal that regulates presynaptic transmitter release in Drosophila. Neuron 20: 305-315, 1998.
10. Del Castillo J and Engbaek L. The nature of the neuromuscular block produced by magnesium. J Physiol 124: 370-384, 1954.
11. Del Castillo J and Katz B. Quantal components of the end-plate potential. J Physiol 124: 560-573, 1954.
12. DiAntonio A, Petersen SA, Heckmann M, and Goodman CS. Glutamate receptor expression regulates quantal size and quantal content at the Drosophila neuromuscular junction. J Neurosci 19: 3023-3032, 1999.
13. Falls DL. Neuregulins: functions, forms, and signaling strategies. Exp Cell Res 284: 14-30, 2003.
14. Falls DL, Rosen KM, Corfas G, Lane WS, and Fischbach GD. ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family. Cell 72: 801-815, 1993.
15. Feng G, Mellor RH, Bernstein M, Keller-Peck C, Nguyen QT, Wallace M, Nerbonne JM, Lichtman JW, and Sanes JR. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28: 41-51, 2000.
16. Fernandes C, Paya-Cano JL, Sluyter F, D'Souza U, Plomin R, and Schalkwyk LC. Hippocampal gene expression profiling across eight mouse inbred strains: towards understanding the molecular basis for behaviour. Eur J Neurosci 19: 2576-2582, 2004.
17. Fischbach GD and Schuetze SM. A post-natal decrease in acetylcholine channel open time at rat end-plates. J Physiol 303: 125-137, 1980.
18. Fontaine B, Klarsfeld A, and Changeux JP. Calcitonin gene-related peptide and muscle activity regulate acetylcholine receptor alpha-subunit mRNA levels by distinct intracellular pathways. J Cell Biol 105: 1337-1342, 1987.
19. + channels in cardiac myocytes. Biochem Biophys Res Commun 308: 23-28, 2003.
20. Fromm L and Rhode M. Neuregulin-1 induces expression of Egr-1 and activates acetylcholine receptor transcription through an Egr-1-binding site. J Mol Biol 339: 483-494, 2004.
21. Haghighi AP, McCabe BD, Fetter RD, Palmer JE, Hom S, and Goodman CS. Retrograde control of synaptic transmission by postsynaptic CaMKII at the Drosophila neuromuscular junction. Neuron 39: 255-267, 2003.
22. Harris JB and Ribchester RR. The relationship between end-plate size and transmitter release in normal and dystrophic muscles of the mouse. J Physiol 296: 245-265, 1979.
23. Katz B and Thesleff S. On the factors which determine the amplitude of the miniature end-plate potential. J Physiol 137: 267-278, 1957.
24. Kramer R, Bucay N, Kane DJ, Martin LE, Tarpley JE, and Theill LE. Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development. Proc Natl Acad Sci USA 93: 4833-4838, 1996.
25. Kues WA, Sakmann B, and Witzemann V. Differential expression patterns of five acetylcholine receptor subunit genes in rat muscle during development. Eur J Neurosci 7: 1376-1385, 1995.
26. Lai KO and Ip NY. Central synapse and neuromuscular junction: same players, different roles. Trends Genet 19: 395-402, 2003a.
27. Lai KO and Ip NY. Postsynaptic signaling of new players at the neuromuscular junction. J Neurocytol 32: 727-741, 2003b.
28. Landmesser LT. Synaptic plasticity: keeping synapses under control. Curr Biol 8: R564-R567, 1998.
29. Loeb JA. Neuregulin: an activity-dependent synaptic modulator at the neuromuscular junction. J Neurocytol 32: 649-664, 2003.
30. Loeb JA, Khurana TS, Robbins JT, Yee AG, and Fischbach GD. Expression patterns of transmembrane and released forms of neuregulin during spinal cord and neuromuscular synapse development. Development 126: 781-791, 1999.
31. Martinou JC, Falls DL, Fischbach GD, and Merlie JP. Acetylcholine receptor-inducing activity stimulates expression of the epsilon-subunit gene of the muscle acetylcholine receptor. Proc Natl Acad Sci USA 88: 7669-7673, 1991.
32. Meyer D, Yamaai T, Garratt A, Riethmacher-Sonnenberg E, Kane D, Theill LE, and Birchmeier C. Isoform-specific expression and function of neuregulin. Development 124: 3575-3586, 1997.
33. Missias AC, Chu GC, Klocke BJ, Sanes JR, and Merlie JP. Maturation of the acetylcholine receptor in skeletal muscle: regulation of the AChR gamma-to-epsilon switch. Dev Biol 179: 223-238, 1996.
34. Missias AC, Mudd J, Cunningham JM, Steinbach JH, Merlie JP, and Sanes JR. Deficient development and maintenance of postsynaptic specializations in mutant mice lacking an "adult" acetylcholine receptor subunit. Development 124: 5075-5086, 1997.
35. Moscoso LM, Chu GC, Gautam M, Noakes PG, Merlie JP, and Sanes JR. Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle. Dev Biol 172: 158-169, 1995.
36. New HV and Mudge AW. Calcitonin gene-related peptide regulates muscle acetylcholine receptor synthesis. Nature 323: 809-811, 1986.
37. Nguyen PV, Duffy SN, and Young JZ. Differential maintenance and frequency-dependent tuning of LTP at hippocampal synapses of specific strains of inbred mice. J Neurophysiol 84: 2484-2493, 2000.
38. Petersen SA, Fetter RD, Noordermeer JN, Goodman CS, and DiAntonio A. Genetic analysis of glutamate receptors in Drosophila reveals a retrograde signal regulating presynaptic transmitter release. Neuron 19: 1237-1248, 1997.
39. Plomp JJ and Molenaar PC. Involvement of protein kinases in the upregulation of acetylcholine release at endplates of alpha-bungarotoxin-treated rats. J Physiol 493: 175-186, 1996.
40. Plomp JJ, van Kempen GT, De Baets MB, Graus YM, Kuks JB, and Molenaar PC. Acetylcholine release in myasthenia gravis: regulation at single end-plate level. Ann Neurol 37: 627-636, 1995.
41. Plomp JJ, van Kempen GT, and Molenaar PC. Adaptation of quantal content to decreased postsynaptic sensitivity at single endplates in alpha-bungarotoxin-treated rats. J Physiol 458: 487-499, 1992.
42. Plomp JJ, van Kempen GT, and Molenaar PC. The upregulation of acetylcholine release at endplates of alpha-bungarotoxin-treated rats: its dependency on calcium. J Physiol 478: 125-136, 1994.
43. Prakash YS and Sieck GC. Age-related remodeling of neuromuscular junctions on type-identified diaphragm fibers. Muscle Nerve 21: 887-895, 1998.
44. Rimer M. Neuregulins: primary or secondary signals for the control of synapse-specific gene expression. J Neurocytol 32: 665-675, 2003.
45. Rimer M, Prieto AL, Weber JL, Colasante C, Ponomareva O, Fromm L, Schwab MH, Lai C, and Burden SJ. Neuregulin-2 is synthesized by motor neurons and terminal Schwann cells and activates acetylcholine receptor transcription in muscle cells expressing ErbB4. Mol Cell Neurosci 26: 271-281, 2004.
46. Rosato Siri MD and Uchitel OD. Calcium channels coupled to neurotransmitter release at neonatal rat neuromuscular junctions. J Physiol 514: 533-540, 1999.
47. Sakmann B and Brenner HR. Change in synaptic channel gating during neuromuscular development. Nature 276: 401-402, 1978.
48. Sandrock AW Jr, Dryer SE, Rosen KM, Gozani SN, Kramer R, Theill LE, and Fischbach GD. Maintenance of acetylcholine receptor number by neuregulins at the neuromuscular junction in vivo. Science 276: 599-603, 1997.
49. Sandrock AW Jr, Goodearl AD, Yin QW, Chang D, and Fischbach GD. ARIA is concentrated in nerve terminals at neuromuscular junctions and at other synapses. J Neurosci 15: 6124-6136, 1995.
50. Sanes JR and Lichtman JW. Induction, assembly, maturation and maintenance of a postsynaptic apparatus. Nat Rev Neurosci 2: 791-805, 2001.
51. Santafe MM, Garcia N, Lanuza MA, Uchitel OD, and Tomas J. Calcium channels coupled to neurotransmitter release at dually innervated neuromuscular junctions in the newborn rat. Neuroscience 102: 697-708, 2001.
52. Santafe MM, Salon I, Garcia N, Lanuza MA, Uchitel OD, and Tomas J. Modulation of ACh release by presynaptic muscarinic autoreceptors in the neuromuscular junction of the newborn and adult rat. Eur J Neurosci 17: 119-127, 2003.
53. Usdin TB and Fischbach GD. Purification and characterization of a polypeptide from chick brain that promotes the accumulation of acetylcholine receptors in chick myotubes. J Cell Biol 103: 493-507, 1986.
54. Zhu X, Lai C, Thomas S, and Burden SJ. Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapses. EMBO J 14: 5842-5848, 1995.