Filaria-induced monocyte dysfunction and its reversal following treatment

Infection and Immunity

Volumn 74, Issue 8, 2006, Pages 4409-4417

  Semnani, Roshanak Tolouei ^a   Keiser, Paul B ^a   Coulibaly, Yaya I ^b   Keita, Falaye ^b   Diallo, Abdallah A ^b   Traore, Diakaridia ^b   Diallo, Dapa A ^b   Doumbo, Ogobara K ^b   Traore, Sekou F ^b   Kubofcik, Joseph ^a   Klion, Amy D ^a   Nutman, Thomas B ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF BAMAKO   (Mali)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ALBENDAZOLE; CATHEPSIN L; CHEMOKINE; CHEMOKINE RECEPTOR CCR7; COLLAPSIN RESPONSE MEDIATOR PROTEIN; CYTOKINE; EXODUS II PROTEIN; GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; HEAT SHOCK PROTEIN; HERMES ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 8; IVERMECTIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PARASITE ANTIGEN; PROTEIN DNAJ; PROTEIN TYROSINE KINASE; RANTES; SPHINGOSINE KINASE 1; STRESS ACTIVATED PROTEIN KINASE 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BRUGIA MALAYI; CELL ADHESION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FILARIASIS; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOSTIMULATION; MALI; MANSONELLA PERSTANS; MICROARRAY ANALYSIS; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; STAPHYLOCOCCUS AUREUS; STATISTICAL ANALYSIS; T LYMPHOCYTE; WUCHERERIA BANCROFTI;

ALBENDAZOLE; ANIMALS; ANTHELMINTICS; ANTIPARASITIC AGENTS; DRUG THERAPY, COMBINATION; ELEPHANTIASIS, FILARIAL; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; IVERMECTIN; MOLECULAR SEQUENCE DATA; MONOCYTES; TREATMENT OUTCOME; WUCHERERIA BANCROFTI;

EID: 33746591697     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01106-05     Document Type: Article

References (31)

1. Agbolade, M., and D. O. Akinboye. 2001. Loa loa and Mansonella perstans infections in Ijebu northwestern Nigeria: a parasitological study. Jpn. J. Infect. Dis. 54:108-110.
2. Allen, J. E., and P. Loke. 2001. Divergent roles for macrophages in lymphatic filariasis. Parasite Immunol. 23:345-352.
3. Bethke, K., F. Staib, M. Distler, U. Schmitt, H. Jonuleit, A. H. Enk, P. R. Galle, and M. Heike. 2002. Different efficiency of heat shock proteins (HSP) to activate human monocytes and dendritic cells: superiority of HSP60. J. Immunol. 169:6141-6148.
4. Boyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand. J. Clin. Lab. Investig. 97:77-89.
5. Chaussabel, D., R. T. Semnani, M. A. McDowell, D. Sacks, A. Sher, and T. B. Nutman. 2003. Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites. Blood 102:672-681.
6. Chaussabel, D., and A. Sher. 2002. Mining microarray expression data by literature profiling. Genome Biol. 3:0055.1-0055.16.
7. Dai, W. J., and B. Gottstein. 1999. Nitric oxide-mediated immunosuppression following murine Echinococcus multilocularis infection. Immunology 97:107-116.
8. Dennis, G., B. T. Sherman, D. A. Hosack, J. Yang, W. Gao, H. C. Lane, and R. A. Lempicki. 2003. DAVID: database for annotation, visualization, and integrated discovery. Genome Biol. 4:P3.
9. Friedland, J. S., R. Shattock, D. G. Remick, and G. E. Griffin. 1993. Mycobacterial 65-kD heat shock protein induces release of proinflammatory cytokines from human monocytic cells. Clin. Exp. Immunol. 91:58-62.
10. + T lymphocytes: a mechanism of immune unresponsiveness in filariasis. Eur. J. Immunol. 32:858-867.
11. Kaifi, J. T., E. Diaconu, and E. Pearlman. 2001. Distinct roles for PECAM-1, ICAM-1, and VCAM-1 in recruitment of neutrophils and eosinophils to the cornea in ocular onchocerciasis (river blindness). J. Immunol. 166:6795-6801.
12. Keiser, P. B., Y. I. Coulibaly, F. Keita, D. Traaore, A. Diallo, D. A. Diallo, R. T. Semnani, O. K. Doumbo, S. F. Traore, A. D. Klion, and T. B. Nutman. 2003. Clinical characteristics of post-treatment reactions to ivermectin/albendazole for Wuchereria bancrofti in a region co-endemic for Mansonella perstans. Am. J. Trop. Med. Hyg. 69:331-335.
13. King, C. L., S. Mahanty, V. Kumaraswami, J. S. Abrams, J. Regunathan, K. Jayaraman, E. A. Ottesen, and T. B. Nutman. 1993. Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset. J. Clin. Investig. 92:1667-1673.
14. Kol, A., T. Bourcier, A. H. Lichtman, and P. Libby. 1999. Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages. J. Clin. Investig. 103:571-577.
15. Liossis, S. N., X. Z. Ding, J. G. Kiang, and G. C. Tsokos. 1997. Overexpression of the heat shock protein 70 enhances the TCR/CD3- and Fas/Apo-1/CD95-mediated apoptotic cell death in Jurkat T cells. J. Immunol. 158:5668-5675.
16. Loke, P., A. S. MacDonald, A. Robb, R. M. Maizels, and J. E. Allen. 2000. Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact. Eur. J. Immunol. 30:2669-2678.
17. Mahanty, S., H. E. Luke, V. Kumaraswami, P. R. Narayanan, V. Vijayshekaran, and, T. B. Nutman. 1996. Stage-specific induction of cytokines regulates the immune response in lymphatic filariasis. Exp. Parasitol. 84:282-290.
18. Mahanty, S., S. N. Mollis, M. Ravichandran, J. A. Abrams, V. Kumaraswami, K. Jayaraman, E. A. Ottesen, and T. B. Nutman. 1996. High levels of spontaneous and parasite antigen-driven interleukin-10 production are associated with antigen-specific hyporesponsiveness in human lymphatic filariasis. J. Infect. Dis. 173:769-773.
19. Maizels, R. M., and M. Yazdanbakhsh. 2003. Immune regulation by helminth parasites: cellular and molecular mechanisms. Nat. Rev. Immunol. 3:733-744.
20. Nutman, T. B., and V. Kumaraswami. 2001. Regulation of the immune response in lymphatic filariasis: perspectives on acute and chronic infection with Wuchereria bancrofti in South India. Parasite Immunol. 23:389-399.
21. Prohaszka, Z., and G. Fust. 2004. Immunological aspects of heat-shock proteins-the optimum stress of life. Mol. Immunol. 41:29-44.
22. Ritter, D. M., and J. H. McKerrow. 1996. Intercellular adhesion molecule 1 is the major adhesion molecule expressed during schistosome granuloma formation. Infect. Immun. 64:4706-4713.
23. Samali, A., and T. G. Cotter. 1996. Heat shock proteins increase resistance to apoptosis. Exp. Cell Res. 223:163-170.
24. Sasisekhar, B., M. Aparna, D. J. Augustin, P. Kaliraj, S. K. Kar, T. B. Nutman, and R. B. Narayanan. 2005. Diminished monocyte function in microfilaremic patients with lymphatic filariasis and its relationship to altered lymphoproliferative responses. Infect. Immun. 73:3385-3393.
25. Semnani, R. T., M. Law, J. Kubofcik, and T. B. Nutman. 2004. Filaria-induced immune evasion: suppression by the infective stage of Brugia malayi at the earliest host-parasite interface. J. Immunol. 172:6229-6238.
26. + T cells. J. Immunol. 171:1950-1960.
27. Semnani, R. T., H. Sabzevari, R. Iyer, and T. B. Nutman. 2001. Filarial antigens impair the function of human dendritic cells during differentiation. Infect. Immun. 69:5813-5822.
28. Srivastava, P. K., A. Menoret, S. Basu, R. J. Binder, and K. L. McQuade. 1998. Heat shock proteins come of age: primitive functions acquire new roles in an adaptive world. Immunity 8:657-665.
29. Tusher, V. G., R. Tibshirani, and G. Chu. 2001. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98:5116-5121.
30. Wanji, S., N. Tendongfor, M. Esum, S. Ndindeng, and P. Enyong. 2003. Epidemiology of concomitant infections due to Loa loa, Mansonella perstans, and Onchocerca volvulus in rain forest villages of Cameroon. Med. Microbiol. Immunol. 192:15-21.
31. Whelan, M., M. M. Harnett, K. M. Houston, V. Patel, W. Harnett, and K. P. Rigley. 2000. A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells. J. Immunol. 164:6453-6460.