Phosphodiesterase-5 Isoforms: Differential Cyclic Guanyl Monophosphate Binding and Cyclic Guanyl Monophosphate Catalytic Activities, and Inhibitory Effects of Sildenafil and Vardenafil

Journal of Urology

Volumn 176, Issue 3, 2006, Pages 1242-1247

  Lin, Guiting ^a,b   Xin, Zhong Cheng ^b   Lue, Tom F ^a,b   Lin, Ching Shwun ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PEKING UNIVERSITY   (China)

Author keywords

penile erection; penis; phosphodiesterase V; sildenafil; vardenafil

Indexed keywords

CYCLIC GUANYL MONOPHOSPHATE; HISTIDINE; PHOSPHATE; PHOSPHODIESTERASE V; SILDENAFIL; UNCLASSIFIED DRUG; VARDENAFIL;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DRUG BINDING; DRUG POTENCY; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN PURIFICATION; WESTERN BLOTTING;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; CYCLIC GMP; HUMANS; IMIDAZOLES; ISOENZYMES; PHOSPHORIC DIESTER HYDROLASES; PIPERAZINES; SULFONES; TRIAZINES;

EID: 33746481784     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2006.04.031     Document Type: Article

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