Estimation of ionized calcium, total calcium and albumin corrected calcium for the diagnosis of hypercalcaemia of malignancy

Journal of the College of Physicians and Surgeons Pakistan

Volumn 16, Issue 1, 2006, Pages 49-52

  Ijaz, Aamir ^a   Mehmood, Tariq ^b   Qureshi, Ayaz Hussain ^b   Anwar, Masood ^a   Dilawar, Muhammad ^a   Hussain, Iftikhar ^c   Khan, Farooq Ahmad ^a   Khan, Dilshad Ahmad ^b   Hussain, Shujaat ^b   Khan, Iqbal Ahmad ^b  

^a ARMED FORCES INSTITUTE OF PATHOLOGY   (Pakistan)

^b ARMY MEDICAL COLLEGE   (Pakistan)

^c National University of Medical Sciences   (Pakistan)

Author keywords

Hypercalcemia; Ionized calcium; Malignancy

Indexed keywords

CALCIUM; PHOSPHORUS; SERUM ALBUMIN;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD; CASE CONTROL STUDY; FEMALE; HUMAN; HYPERCALCEMIA; MALE; METABOLISM; MIDDLE AGED; NEOPLASM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CALCIUM; CASE-CONTROL STUDIES; FEMALE; HUMANS; HYPERCALCEMIA; MALE; MIDDLE AGED; NEOPLASMS; PHOSPHORUS; SERUM ALBUMIN;

EID: 33746477081     PISSN: 1022386X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Bayne MC, Illidge TM. Hypercalcemia, parathyroid hormonerelated protein and malignancy. Clin Oncol (R Coll Radiol) 2001; 13: 372-7.
2. Pfeilschifter J. Hypercalcaemic crisis. Internist (Berl) 2003; 44: 1231-6.
3. Shuey KM, Brant JM. Hypercalcemia of malignancy: Part II. Clin J Oncol Nurs 2004; 8: 321-3.
4. Stewart AF, Insogna KL, Broadus AE. Malignancy associated hypercalcemia. In: DeGroot LJ, (edi). Endocrinology. 2nd ed. Philadelphia: W. B. Saunders, 1989; 967-70.
5. Esbrit P. Hypercalcemia of malignancy--new insights into an old syndrome. Clin Lab 2001; 47: 67-71.
6. Hiraki A, Ueoka H, Takata I, Gemba K, Bessho A, Segawa Y, et al. Hypercalcemia-leukocytosis syndrome associated with lung cancer. Lung Cancer 2004; 43: 301-7.
7. Devys A, Lortholary A, Audran M. PTHrP and breast cancer. Bull Cancer 2001; 88: 1075-80.
8. Fujikawa M, Takata Y, Okamura K, Nakagawa M, Tateishi A, Kurokawa H, et al. Hypercalcemia associated with parathyroid hormone-related protein at the terminal stage of uncomplicated squamous cell carcinoma in the head and neck region. Head Neck 2002; 24: 56-62.
9. Adiga GU, Dutcher JP, Larkin M, Garl S, Koo J. Characterisation of bone metastases in patients with renal cell cancer. BJU Int 2004; 93: 1237-40.
10. des Grottes JM, Dumon JC, Body JJ. Hypercalcemia of melanoma: incidence, pathogenesis and therapy with bisphosphonates. Melanoma Res 2001; 11: 477-82.
11. Mansoor S, Siddiqui I, Adil S, Kakepeto GN, Fatmi Z. Frequency of hypercalcemia in patients of multiple myeloma in Karachi. J Coll Physicians Surg Pak 2005; 15: 409-12.
12. Okada Y, Tsukada J, Nakano K, Tonai S, Mine S, Tanaka Y. Macrophage inflammatory protein-1alpha induces hypercalcemia in adult T-cell leukaemia. J Bone Miner Res 2004; 19: 1105-11.
13. Matsuhashi Y, Tasaka T, Uehara E, Fujimoto M, Fujita M, Tamura T, et al. Diffuse large B-cell lymphoma presenting with hypercalcemia and multiple osteolysis. Leuk Lymphoma 2004; 45: 397-400.
14. James RA, Quinton R, Ball SG. Endocrinology and systemic disease. In: Harris PE, Bouloux PG. Endocrinology in clinical practice. London: Martin Dunitz 2003; 353-5.
15. David BE, Robert KR. Mineral and bone metabolism. In: Burtis CA, Edward RA, (edi). Teitz textbook of clinical chemistry. 3rd ed. Philadelphia: W. B. Saunders, 1999; 1403-6.
16. Thode J, Juul-Jorgensen B, Bhatia HM, Kjaerulf-Nielsen M, Bartels PD, Fogh-Andersen N, et al. Ionized calcium, total calcium and albumin corrected calcium in the serum in 1213 patients with suspected calcium metabolic diseases. A prospective multicenter study. Ugeskr Laeger 1989; 151: 2423-5.
17. Toffaletti JG, Wildermann RF. The effects of heparin anticoagulants and fill volume in blood gas syringes on ionized calcium and magnesium measurements. Clin Chem Acta 2001; 304: 147-51.
18. Walmsley RN, White GH. A guide to clinical chemistry. 3rd ed. London. Blackwell Scientific Publications 1994. 186-95.
19. Meng X, Xing X, Liu S. The diagnosis of primary hyperparathyroidism- analysis of 134 cases. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1994; 16: 13-9.
20. Sorva A, Elfving S, Pohja P, Tilvis RS. Assessment of calcaemic status in geriatric hospital patients: serum ionized calcium versus albumin-adjusted total calcium. Scand J Clin Lab Invest 1988; 48: 489-94.
21. Riancho JA, Arjona R, Sanz J, Olmos JM, Valle R, Barcelo JR, et al. Is the routine measurement of ionized calcium worthwhile in patients with cancer? Postgrad Med J 1991; 67: 350-3.
22. Toffaletti J. Total, ultrafiltrable, dialysable and ionized calcium measurements in randomly selected samples compared with clinical diagnoses. Ann Clin Biochem 1983; 20: 349-52.
23. Teachout DJ, Taylor SM. A comparison of serum ionized calcium concentrations and serum total calcium concentrations in dogs with lymphoma. Zentralbl Veterinarmed A 1997; 44: 195-200.
24. Annesley TM, Burritt MF, Kyle RA. Artifactual hypercalcemia in multiple myeloma. Mayo Clin Proc 1982; 57: 572-5.
25. Rudnicki M, Thode J, Jorgensen T, Heitmann BL, Sorensen OH. Effects of age, sex, season and diet on serum ionised calcium, parathyroid hormone and vitamin D in a random population. J Intern Med 1993; 234: 195-200.
26. Motellon JL, Javort Jimenez F, de Miguel F, Jaras MJ, Diaz A, Hurtado J, et al. Parathyroid hormone-related protein, parathyroid hormone, and vitamin D in hypercalcemia of malignancy. Clin Chim Acta 2000; 290: 189-97.
27. Nakanishi M, Ide M, Kawashima M, Kuwamura M, Kumagai D, Sawamoto O, et al. Establishment of a transplantable rat pulmonary carcinoma-derived cell line (IP-B12) as a new model of humoral hypercalcemia of malignancy and bone metastasis. Tumour Biol 2003; 24: 70-6.
28. Uy HL, Mundy GR, Boyce BF, Story BM, Dunstan CR, Yin JJ, et al. Tumour necrosis factor enhances parathyroid hormone-related protein-induced hypercalcemia and bone resorption without inhibiting bone formation in vivo. Cancer Res 1997; 57: 3194-9.
29. Itani O, Tsang R. Bone disease. In: Kaplan LA, Pesce AJ, Kazimieczak SC, (edi). Clinical chemistry; theory, analysis and correlation. 4th ed. Philladelphia: Mosby 2003; 527.