Adult calcific aortic stenosis and Chlamydia pneumoniae: The role of Chlamydia infection in valvular calcification

Israel Medical Association Journal

Volumn 8, Issue 7, 2006, Pages 464-468

  Turgeman, Yoav ^a   Levahar, Pierre ^a   Lavi, Idit ^b   Shneor, Amir ^a   Colodner, Raoul ^a   Samra, Zmira ^c   Bloch, Lev ^a   Rosenfeld, Tiberio ^a  

^a HAEMEK MEDICAL CENTER   (Israel)

^b CARMEL MEDICAL CENTER   (Israel)

^c Rabin   (Israel)

Author keywords

Adult calcific aortic stenosi; Aging; Chlamydia pneumoniae; Immunoglobulins

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ADULT; AGED; ANTIBODY TITER; AORTA STENOSIS; ARTICLE; CALCIFICATION; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; DISEASE SEVERITY; ECHOCARDIOGRAPHY; FEMALE; HUMAN; IMMUNOFLUORESCENCE; MALE; PREVALENCE; STATISTICAL ANALYSIS;

AGED; AGED, 80 AND OVER; AORTIC VALVE STENOSIS; CARDIOMYOPATHIES; CARDIOTONIC AGENTS; CHLAMYDOPHILA PNEUMONIAE; ECHOCARDIOGRAPHY; FEMALE; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALE; MIDDLE AGED; PNEUMONIA, BACTERIAL; SEVERITY OF ILLNESS INDEX;

EID: 33746456320     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Otto CM, Lind BK, Kitzman DW, Gersh BJ, Siscovick DS Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med 1999;341:142-7.
2. Lindroos M, Kupari M, Heikkila J, Tilvis R. Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample. J Am Coll Cardiol 1993;21:1220-5.
3. Stoke W. The Disease of the Heart and Aorta. Dublin: Hodges & Smith, 1845:211-12.
4. Rajamannan NM, Gersh B, Bonow RO. Calcific aortic stenosis: from bench to the bedside - emerging clinical and cellular concepts. Heart 2003;89:801-5
5. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801-9.
6. Kou CC, Shor A, Campbell LA, Fukushi H, Patton DL, Graystone JT. Demonstration of Chlamydia pneumoniae in athrosclerotic lesion of coronary arteries. J Infect Dis 1993;167:841-9.
7. Taylor R. Evaluation of the continuity equation in the Doppler echocardiographic assessment of the severity of valvular aortic stenosis. J Am Soc Echocardiogr 1990;3:326-30.
8. Braunwald E. Valvular heart disease. In: Braunwald E, Zips DP, Libby P. Heart Disease. A Textbook of Cardiovascular Medicine Philadelphia: WB Saunders, 2003:1671-80.
9. Boman J, Hammerschlag MR. Chlamydia pneumonia and atherosclerosis: critical assessment of diagnostic methods and relevance to treatment studies. Clin Microbiol Rev 2002;15:1-20.
10. Hoppichler F, Lechleitner M, Traweger C, et al. Changes of serum antibodies to heat-shock protein 65 in coronary heart disease and myocardial infarction. Atherosclerosis 1996;126:333-8.
11. Otto CM, Kuusisto J, Reichenbach DD, Gown AM, O'Brien KD. Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies Circulation 1994;90:844-53.
12. Glader CA, Birgander LS, Soderberg S, et al. Lipoprotein(a), Chlamydia pneumoniae, leptin and tissue plasminogen activator as risk markers for valvular aortic stenosis. Eur Heart J 2003;24:198-208.
13. Novaro GM, Tiong TY, Pearce GL, Lauer GK, Sprecher KL, Griffin BP. Effect of hydroxymethylglutaryl coenzyme A reductase inhibitors on the progression of calcific aortic stenosis. Circulation 2001;104:2205-9.
14. Sahasakul Y, Edwards WD, Naessens JM, Tajik AJ. Age-related changes in aortic and mitral valve thickness: implications for two-dimensional echocardiography based on an autopsy study of 200 normal human hearts. Am J Cardiol 1988;62:424-30
15. Rahimtoola SH. The year in valvular heart disease. J Am Coll Cardiol 2004;43:491-504.
16. Wongpraparut N, Apiyasawat S, Crespo G, Yazdani K, Jacobs LE, Kotler MN. Determinants of progression of aortic stenosis in patients aged ≥ 40 years. Am J Cardiol 2002;89:350-2.
17. Mohler ER 3rd, Gannon F, Reynolds C, Zimmerman R, Keane MG, Kaplan FS. Bone formation and inflammation in cardiac valves. Circulation 2001;103:1522-8.
18. Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997;336:973-9.
19. Jung KH, Chu K, Jeong SW, et al. HMG-CoA reductase inhibitor, atorvastatin, promotes sensory motor recovery, suppressing acute inflammatory reaction after experimental intracerebral hemorrhage. Stroke 2004;35:1744-9.
20. de Cunha V, Tham DM, Martin-McNulty B, et al. Enalapril attenuates angiotensin II-induced atherosclerosis and vascular inflammation. Atherosclerosis 2005;178:9-17.
21. Saikku P, Leinonen K, Mattila MR, et al. Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and myocardiol infarction. Lancet 1988;ii:983-6.
22. Juvonen J, Juvonen T, Lurila A, et al. Can degenerative aortic valve stenosis be related to persistent Chlamydia pneumoniae infection? Ann Intern Med 1998;128:741-4.
23. Gaydos CA, Summersgill JT, Sahney NN, Ramirez JA, Quinn TC. Replication of Chlamydia pneumonia in vitro in human macrophages, endothelial cells and aortic smooth muscle cells. Infect Immun 1996;64:1614-20.
24. Heinemann M, Susa M, Simnacher U, Marre R, Essig A. Growth of Chlamydia pneumoniae induces cytokine production and expression of CD14 in a human monocyte cell line. Infect Immun 1996;64:4872-87.
25. Andraws R, Berger JS, Brown DL. Effects of antibiotic therapy on outcomes of patients with coronary artery disease: a meta-analysis of randomized controlled trials. JAMA 2005;293:2641-7.