Model-based analysis of clinical fluorescence spectroscopy for in vivo detection of cervical intraepithelial dysplasia

Journal of Biomedical Optics

Volumn 11, Issue 2, 2006, Pages

  Chang, Sung K ^a   Marin, Nena ^b   Follen, Michele ^c   Richards Kortum, Rebecca ^d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b The University of Texas at Austin   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d Rice University   (United States)

Author keywords

Cervical cancer; Diagnosis; Fluorescence spectroscopy

Indexed keywords

ARTICLE; BIOLOGICAL MODEL; CLASSIFICATION; CLINICAL TRIAL; COMPUTER ASSISTED DIAGNOSIS; COMPUTER SIMULATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; METHODOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPECTROFLUOROMETRY; UTERINE CERVIX CARCINOMA IN SITU; VALIDATION STUDY;

CERVICAL INTRAEPITHELIAL NEOPLASIA; COMPUTER SIMULATION; DIAGNOSIS, COMPUTER-ASSISTED; FEMALE; HUMANS; MODELS, BIOLOGICAL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE;

DIAGNOSIS; MATHEMATICAL MODELS; MEDICAL IMAGING; TISSUE;

CERVICAL INTRAEPITHELIAL DYSPLASIA; DYSPLASTIC TRANSFORMATION; EPITHELIAL FLAVIN ADENINE DINUCLEOTIDE (FAD) FLUORESCENCE; EPITHELIAL KERATIN FLUORESCENCE;

FLUORESCENCE;

EID: 33746409759     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2187979     Document Type: Article

References (42)

1. R. Etzioni, N. Urban, S. Ramsey, M. McIntosh, S. Schwartz, B. Reid, J. Radich, G. Anderson, and L. Hartwell, "The case for early detection", Nat. Rev. Cancer 3, 243-252 (2003). (Pubitemid 37328860)
2. K. Sokolov, M. Follen, and R. Richards-Kortum, "Optical spectroscopy for detection of neoplasia", Curr. Opin. Chem. Biol. 6, 651-658 (2002). (Pubitemid 35284197)
3. U. Utzinger and R. R. Richards-Kortum, "Fiber optic probes for biomedical optical spectroscopy", J. Biomed. Opt. 8, 121-147 (2003).
4. S. K. Chang, M. Follen, A. Malpica, U. Utzinger, G. Staerkel, D. Cox, E. N. Atkinson, C. MacAulay, and R. Richards-Kortum, "Optimal excitation wavelengths for discrimination of cervical neoplasia", IEEE Trans. Biomed. Eng. 49, 1102-1111 (2002).
5. W. K. Huh, R. M. Cestero, F. A. Garcia, M. A. Gold, R. S. Guido, K. McIntyre-Seltman, D. M. Harper, L. Burke, S. T. Sum, R. F. Flewelling, and R. D. Alvarez, "Optical detection of high-grade cervical intraepithelial neoplasia in vivo: results of a 604-patient study", Am. J. Obstet. Gynecol. 190, 1249-1257 (2004). (Pubitemid 38692205)
6. I. Georgakoudi, E. E. Sheets, M. G. Muller, V. Backman, C. P. Crum, K. Badizadegan, R. R. Dasari, and M. S. Feld, "Trimodal spectroscopy for the detection and characterization of cervical precancers in vivo", Am. J. Obstet. Gynecol. 186, 374-382 (2002). (Pubitemid 34234144)
7. R. J. Nordstrom, L. Burke, J. M. Niloff, and J. F. Myrtle, "Identification of cervical intraepithelial neoplasia (CIN) using UV-excited fluorescence and diffuse-reflectance tissue spectroscopy", Lasers Surg. Med. 29, 118-127 (2001). (Pubitemid 32808299)
8. C. Zhu, G. M. Palmer, T. M. Breslin, F. Xu, and N. Ramanujam, "Use of a multiseparation fiber optic probe for the optical diagnosis of breast cancer", J. Biomed. Opt. 10, 024032 (2005).
9. M. G. Muller, I. Geogakoudi, Q. Zhang, J. Wu, and M. S. Feld, "Intrinsic fluorescence spectroscopy in turbid media: disentangling effects of scattering and absorption", Appl. Opt. 40, 4633-4646 (2001).
10. D. L. Heintzelman, U. Utzinger, H. Fuchs, A. Zuluaga, K. Gossage, A. M. Gillenwater, R. Jacob, B. Kemp, and R. R. Richards-Kortum, "Optimal excitation wavelengths for in vivo detection of oral neoplasia using fluorescence spectroscopy", Photochem. Photobiol. 72, 103-113 (2000).
11. G. M. Palmer, P. J. Keely, T. M. Breslin, and N. Ramanujam, "Autofluorescence spectroscopy of normal and malignant human breast cell lines", Photochem. Photobiol. 78, 462-469 (2003).
12. C. Millot, P. Bondza-Kibangou, J. M. Millot, A. Lallemand, and M. Manfait, "Autofluorescence spectroscopy of malpighian epithelial cells, as a new tool for analysis of cervical cancer precursors", Histol. Histopathol 18, 479-485 (2003). (Pubitemid 36362066)
13. I. Pavlova, K. Sokolov, R. Drezek, A. Malpica, M. Follen, and R. Richards-Kortum, "Microanatomical and biochemical origins of normal and precancerous cervical autofluorescence using laser-scanning fluorescence confocal microscopy", Photochem. Photobiol. 77, 550-555 (2003).
14. I. Georgakoudi, B. C. Jacobson, M. G. Muller, E. E. Sheets, K. Badizadegan, D. L. Carr-Locke, C. P. Crum, C. W. Boone, R. R. Dasari, J. Van Dam, and M. S. Feld, "NAD (P) H and collagen as in vivo quantitative fluorescent biomarkers of epithelial precancerous changes", Cancer Res. 62, 682-687 (2002). (Pubitemid 34126941)
15. C. K. Brookner, M. Follen, I. Boiko, J. Galvan, S. Thomsen, A. Malpica, S. Suzuki, R. Lotan, and R. Richards-Kortum, "Autofluorescence patterns in short-term cultures of normal cervical tissue", Photochem. Photobiol. 71, 730-736 (2000).
16. S. K. Chang, M. Y. Dawood, G. Staerkel, U. Utzinger, E. N. Atkinson, R. R. Richards-Kortum, and M. Follen, "Fluorescence spectroscopy for cervical precancer detection: is there variance across the menstrual cycle?" J. Biomed. Opt. 7, 595-602 (2002). (Pubitemid 35459941)
17. J. R. Mourant, M. Canpolat, C. Brocker, O. Esponda-Ramos, T. M. Johnson, A. Matanock, K. Stetter, and J. P. Freyer, "Light scattering from cells: the contribution of the nucleus and the effects of proliferative status", J. Biomed. Opt. 5, 131-137 (2000).
18. R. Drezek, M. Guillaud, T. Collier, I. Boiko, A. Malpica, C. Macaulay, M. Follen, and R. Richards-Kortum, "Light scattering from cervical cells throughout neoplastic progression: influence of nuclear morphology, DNA content, and chromatin texture", J. Biomed. Opt. 8, 7-16 (2003).
19. D. Arifler, M. Guillaud, A. Carraro, A. Malpica, M. Follen, and R. Richards-Kortum, "Light scattering from normal and dysplastic cervical cells at different epithelial depths: finite-difference time-domain modeling with a perfectly matched layer boundary condition", J. Biomed. Opt. 8, 484-494 (2003).
20. T. Collier, D. Arifler, A. Malpica, M. Follen, and R. Richards-Kortum, "Determination of epithelial tissue scattering coefficient using confocal microscopy", IEEE J. Quantum Electron. 9, 307-313 (2003).
21. G. Zonios, L. T. Perelman, V. M. Backman, R. Manoharan, M. Fitzmaurice, J. Van Dam, and M. S. Feld, "Diffuse reflectance spectroscopy of human adenomatous colon polyps in vivo", Appl. Opt. 38, 6628-6637 (1999). (Pubitemid 129567570)
22. J. Wu, M. S. Feld, and R. P. Rava, "Analytical model for extracting intrinsic fluorescence in turbid media", Appl. Opt. 32, 3585-3595 (1993).
23. M. S. Nair, N. Ghosh, N. S. Raju, and A. Pradhan, "Determination of optical parameters of human breast tissue from spatially resolved fluorescence: a diffusion theory model", Appl. Opt. 41, 4024-4035 (2002). (Pubitemid 34802322)
24. J. C. Finlay and T. H. Foster, "Recovery of hemoglobin oxygen saturation and intrinsic fluorescence with a forward-adjoint model", Appl. Opt. 44, 1917-1933 (2005). (Pubitemid 40479543)
25. D. Stasic, T. J. Farrell, and M. S. Patterson, "The use of spatially resolved fluorescence and reflectance to determine interface depth in layered fluorophore distributions", Phys. Med. Biol. 48, 3459-3474 (2003). (Pubitemid 37427948)
26. S. K. Chang, D. Arifler, R. Drezek, M. Follen, and R. Richards-Kortum, "Analytical model to describe fluorescence spectra of normal and preneoplastic epithelial tissue: comparison with Monte Carlo simulations and clinical measurements", J. Biomed. Opt. 9, 511-522 (2004).
27. R. J. Kurman, Ed., Pathology of the Female Genital Tract, Springer-Verlag, New York (1987).
28. N. Marin, N. MacKinnon, C. MacAulay, S. K. Chang, E. Atkinson, D. Cox, D. Serashitopol, M. Follen, and R. Richards-Kortum, "Calibration standards for multi-center clinical trials of fluorescence spectroscopy for in vivo diagnosis", J. Biomed. Opt. 11(1), 014010 (2006).
29. R. S. Da Costa, H. Andersson, and B. C. Wilson, "Molecular fluorescence excitation-emission matrices relevant to tissue spectroscopy", Photochem. Photobiol. 78, 384-392 (2003).
30. K. Sokolov, J. Galvan, A. Myakov, A. Lacy, R. Lotan, and R. Richards-Kortum, "Realistic three-dimensional epithelial tissue phantoms for biomedical optics", J. Biomed. Opt. 7, 148-156 (2002). (Pubitemid 34278422)
31. D. R. Eyre, M. A. Paz, and P. M. Gallop, "Cross-linking in collagen and elastin", Annu. Rev. Biochem. 53, 717-748 (1984). (Pubitemid 14059149)
32. V. M. Monnier, R. R. Kohn, and A. Cerami, "Accelerated age-related browning of human collagen in diabetes mellitus", Proc. Natl. Acad. Sci. U. S. A. 81, 583-587 (1984). (Pubitemid 14186609)
33. J. R. Mourant, J. P. Freyer, A. H. Hielscher, A. A. Eick, D. Shen, and T. M. Johnson, "Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics", Appl. Opt. 37, 3586-3593 (1998). (Pubitemid 128658703)
34. I. S. Saidi, "Transcutaneous optical measurement of hyperbilirubinemia in Neonates", Thesis (1992).
35. D. C. Walker, B. H. Brown, A. D. Blackett, J. Tidy, and R. H. Smallwood, "A study of the morphological parameters of cervical squamous epithelium", Physiol. Meas 24, 121-135 (2003). (Pubitemid 36330460)
36. J. J. More and D. C. Sorensen, "Computing a trust region step", SIAM (Soc. Ind. Appl. Math.) J. Sci. Stat. Comput. 4, 553-572 (1983).
37. R. Drezek, K. Sokolov, U. Utzinger, I. Boiko, A. Malpica, M. Follen, and R. Richards-Kortum, "Understanding the contributions of NADH and collagen to cervical tissue fluorescence spectra: modeling, measurements, and implications", J. Biomed. Opt. 6, 385-396 (2001). (Pubitemid 34220957)
38. M. C. Skala, J. M. Squirrell, K. M. Vrotsos, J. C. Eickhoff, A. Gendron-Fitzpatrick, K. W. Eliceiri, and N. Ramanujam, "Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues", Cancer Res. 65, 1180-1186 (2005). (Pubitemid 40270142)
39. Y. C. Wu, P. Xi, J. A. Y. Qu, T. H. Cheung, and M. Y. Yu, "Depthresolved fluorescence spectroscopy reveals layered structure of tissue", Opt. Express 12, 3218-3223 (2004).
40. C. Carrilho, M. Alberto, L. Buane, and L. David, "Keratins 8, 10, 13, and 17 are useful markers in the diagnosis of human cervix carcinomas", Hum. Pathol. 35, 546-551 (2004). (Pubitemid 38656937)
41. R. Drezek, C. Brookner, I. Pavlova, I. Boiko, A. Malpica, R. Lotan, M. Follen, and R. Richards-Kortum, "Autofluorescence microscopy of fresh cervical-tissue sections reveals alterations in tissue biochemistry with dysplasia", Photochem. Photobiol. 73, 636-641 (2001).
42. M. Guillaud, D. Cox, K. Adler-Storthz, A. Malpica, G. Staerkel, J. Matisic, D. Van Niekerk, N. Poulin, M. Follen, and C. MacAulay, "Exploratory analysis of quantitative histopathology of cervical intraepithelial neoplasia: objectivity, reproducibility, malignancy-associated changes, and human papillomavirus", Cytometry 60, 81-89 (2004). (Pubitemid 38859204)