Systemic NF-κB activation in blood cells of breast cancer patients

Redox Report

Volumn 11, Issue 1, 2006, Pages 39-44

  Adžić, Miroslav ^a   Nićiforović, Ana ^a   Vučić, Vesna ^a   Nešković Konstantinović, Zora ^b   Spasić, Snežana D ^c   Jones, David R ^d   Radojčić, Marija B ^a   Spasić, Mihajlo B ^d  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b INSTITUTE FOR ONCOLOGY AND RADIOLOGY OF SERBIA   (Serbia)

^c IChTM   (Serbia)

^d UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Breast cancer; CAT; Mn SOD; NF B

Indexed keywords

ANTIOXIDANT; CATALASE; CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; GLUTATHIONE PEROXIDASE; HEMOGLOBIN; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; ANTINEOPLASTIC AGENT; SUPEROXIDE DISMUTASE;

ADULT; ARTICLE; BLOOD CELL; BLOOD SAMPLING; BREAST CANCER; CELL INVASION; CELL LYSATE; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ERYTHROCYTE COUNT; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTE COUNT; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; BLOOD; BREAST TUMOR; COMPARATIVE STUDY; DRUG EFFECT; ENZYME ACTIVATION; ERYTHROCYTE; LEUKOCYTE; METABOLISM; MIDDLE AGED;

ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CATALASE; CYCLOPHOSPHAMIDE; DOXORUBICIN; ENZYME ACTIVATION; ERYTHROCYTES; FEMALE; FLUOROURACIL; HEMOGLOBINS; HUMANS; HYDROGEN PEROXIDE; LEUKOCYTES; MIDDLE AGED; NF-KAPPA B; SUPEROXIDE DISMUTASE;

EID: 33746361222     PISSN: 13510002     EISSN: 13510002     Source Type: Journal    
DOI: 10.1179/135100006X101002     Document Type: Article

References (47)

1. Ellis PA, Smith IE, Detre S et al. Reduced apoptosis and proliferation and increased Bcl-2 in residual breast cancer following preoperative chemotherapy. Breast Cancer Res Treat 1998; 48: 107-116.
2. Cristofanilli M, Buydar AM, Hortobagyi GN. Update on the management of inflammatory breast cancer. Oncologist 2003; 8: 141-148.
3. Baldini E, Gardin G, Giannessi PG et al. Accelerated versus standard cyclophosphamide, epirubicin and 5-fluorouracil or cyclophosphamide, methotrexate and 5-fluorouracil: a randomized phase III trial in locally advanced breast cancer. Ann Oncol 2003; 14: 227-232.
4. Friedrichs K, Holzel F, Janicke F. Combination of taxanes and anthracyclines in first-line chemotherapy of metastatic breast cancer: an interim report. Eur J Cancer 2002; 38: 1730-1738.
5. Sangeetha P, Das UN, Koratkar R, Suryaprabha P. Increase in free radical generation and lipid peroxidation following chemotherapy in patients with cancer. Free Radic Biol Med 1990; 8: 15-19.
6. Weijl NI, Cleton FJ, Osanto S. Free radicals and antioxidants in chemotherapy-induced toxicity. Cancer Treat Rev 1997; 23: 209-240.
7. Mignotte B, Vayssiere JL. Mitochondria and apoptosis. Eur J Biochem 1998; 252: 1-15.
8. Hellman S. Principles of radiation therapy. In: DeVita VT, Hellman S, Rosenberg SA. (eds) Cancer: principles and practice of oncology, 4th edn. Philadelphia, PA: J.B. Lippincott, 1993.
9. Rohrdanz E, Kahl R. Alterations of antioxidant enzyme expression in response to hydrogen peroxide. Free Radic Biol Med 1998; 24: 27-38.
10. Wispe JR, Clark JC, Burhans MS, Dropp KE, Korfhagen TR, Whitsett JA. Synthesis and processing of the precursor for human mangano-superoxide dismutase. Biochim Biophys Acta 1989; 994: 30-36.
11. Shimoda-Matsubayashi S, Matsumine H, Kobayashi T, Nakagawa-Hattori Y, Shimizu Y, Mizuno Y. Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease. Biochem Biophys Res Commun 1996; 226: 561-565.
12. Costantini P, Jacotot E, Decaudin D, Kroemer G. Mitochondrion as a novel target of anticancer chemotherapy. J Natl Cancer Inst 2000; 92: 1042-1053.
13. Sun Y. Free radicals, antioxidant enzymes and carcinogenesis. Free Radic Biol Med 1990; 8: 583-599.
14. Singh SV, Brunner T, Roberts B, Krishan A. Differential expression of glutathione S-transferase, glutathione peroxidase and glutathione reductase in normal and malignant human breast tissues. Cancer Lett 1990; 15: 43-48.
15. Afrasyap L, Guvenen G, Turkmen S. Plasma and erythrocyte total antioxidant status in patients with benign and malignant breast disease. Cancer Biochem Biophys 1998; 16: 129-138.
16. Kumaraguruparn R, Subapriya R, Viswanathan P, Nagini S. Tissue lipid peroxidation and antioxidant status in patients with adenocarcinoma of the breast. Clin Chim Acta 2002; 325: 165-170.
17. Kumaraguruparn R, Kabalimoortthy J, Nagini S. Correlation of tissue lipid peroxidation and antioxidants with clinical stage and menopausal status in patients with adenocarcinoma of the breast. Clin Biochem 2005; 38: 154-158.
18. Gibananada R, Sanjay B, Nooton KS, Suryanarayan D, Vinod R, Seetharaman A, Syed AH. Lipid peroxidation, free radical production and antioxidant status in breast cancer. Breast Cancer Res Treat 2000; 59: 63-70.
19. Baichwal VR, Baeuerle PA. Activate NF-kappa B or die? Curr Biol 1997; 7: R94-R96.
20. Baeuerle PA, Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 1994; 12: 141-179.
21. Yeh CC, Wan XS, St Clair DK. Transcriptional regulation of the 5V proximal promoter of the human manganese superoxide dismutase gene. DNA Cell Biol 1998; 17: 921-930.
22. Verma IM, Stevenson JK, Schwartz EM, Van Antwerp D, Miyamoto S. Rel/ NF-kappa B/I kappa B family: intimate tales of association and dissociation. Genes Dev 1995; 9: 2723-2735.
23. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Polin phenol reagent. J Biol Chem 1951; 193: 265-267.
24. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-685.
25. McCord JM, Fridovich I. Superoxide dismutase. An enzyme function for erythrocuprein (hemocprein). J Biol Chem 1969; 224: 6049-6055.
26. Claiborne A. Catalase activity. In: Greenwald RA. (eds) Handbook of Methods for Oxygen Radical Research. Boca Raton, FL: CRC, 1985; 283-284.
27. Kinnula VL, Crapo JD. Superoxide dismutases in malignant cells and human tumors. Free Radic Biol Med 2004; 36: 718-744.
28. Halliwell B. Oxidative stress in cell culture: an under-appreciated problem? FEBS Lett 2003; 540: 3-6.
29. Bolzan AD, Bianchi NO, Larramedly ML, Bianchi MS. Chromosomal sensitivity of human lymphocytes to bleomycin. Influence of antioxidant enzymes activities in whole blood and different blood fractions. Cancer Genet Cytogenet 1992; 64: 133-138.
30. Bolzan AD, Bianchi MS, Bianchi NO. Superoxide dismutase, catalase and glutathione peroxidase activities in human blood: influence of sex, age and cigarette smoking. Clin Biochem 1997; 30: 449-454.
31. Michelson MA. Selenium glutathione peroxidase: some aspects in man. J Environ Pathol Toxicol Oncol 1998; 17: 233-239.
32. Markovic S, Vukajlovic D, Ognjanovic B et al. A comparative study of the effects of molsidomine and 3-morpholinosydnonimine on the redox status of rat erythrocytes and reticulocytes. Cell Biochem Funct 2006 Jan 6; [Epub ahead of print] Digital Object Identifier 10.1002/cbf 1320.
33. Fang Y-Z, Yang S, Wu G. Free radicals, antioxidants, and nutrition. Nutrition 2002; 18: 872-879.
34. Abiaka C, Al-Awadi F, Al-Sayer H, Gulshan S, Behbehani A, Farghally M. Activities of erythrocyte antioxidant enzymes in cancer patients. J Clin Lab Anal 2002; 16: 167-171.
35. Yeh C-C, Hou, M-F, Tsai S-M et al. Superoxide anion radical, lipid peroxides and antioxidant status in the blood of patients with breast cancer. Clin Chim Acta 2005; 361: 104-111.
36. 2O2 , and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J 1993; 12: 2005-2015.
37. Schreck R, Albermann K, Baeuerle PA. Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells. Free Radic Res Commun 1992; 17: 221-237.
38. Xu YKK, Kiningham M, Devataraja N et al. An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta. DNA Cell Biol 1999; 18: 709-722.
39. Wang S, Leonard SS, Castranova V, Vallyathan V, Shi X. The role of superoxide radical in TNF-α induced NF-κB activation. Ann Clin Lab Sci 1999; 29: 192-199.
40. Aota K, Azuma M, Yamashita T et al. 5-Fluorouracil induces apoptosis trough the suppression of NF-κB activity in human salivary gland cancer cells. Biochem Biophys Res Commun 2000; 273: 1168-1174.
41. Bernard D, Monte D, Vandenbunder B, Abbadie C. The c-Rel transcription factor can both induce and inhibit apoptosis in the same cells via the upregulation of MnSOD. Oncogene 2002; 21: 4392-4402.
42. Li Y, Huang T, Carlson EJ et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 1995; 11: 376-381.
43. Yen HC, Oberley TD, Vichitbandha S, Ho YS, St Clair DK. The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice. J Clin Invest 1996; 98: 1253-1260.
44. Tolando R, Jovanovic A, Brigelius-Flohe R, Ursini F, Maiorino M. Reactive oxygen species and proinflammatory cytokine signaling in endothelial cells: effect of selenium supplementation. Free Radic Biol Med 2000; 28: 979-986.
45. Weiss SJ, LoBuglio AF. Biology of disease phagocytogenerated oxygen metabolites and cellular injury. Lab Invest 1982; 7: 5-18
46. Keno Y, Fridovich I. Superoxide radical inhibits catalase. J Biol Chem 1975; 257: 5751-5754.
47. Piegeolet E, Corbisier P. GPx and SOD and catalase inactivation by AO. Mech Age Dev 1990; 51: 283-297.