-
1
-
-
0025876404
-
A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis
-
Poupon RE, Balkau B, Eschwege E, Poupon R. A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. N Engl J Med 1991; 324: 1548-1554
-
(1991)
N Engl J Med
, vol.324
, pp. 1548-1554
-
-
Poupon, R.E.1
Balkau, B.2
Eschwege, E.3
Poupon, R.4
-
2
-
-
0033604026
-
Randomised controlled trials of ursodeoxycholic-acid therapy for primary biliary cirrhosis: A meta-analysis
-
Goulis J, Leandro G, Burroughs AK. Randomised controlled trials of ursodeoxycholic-acid therapy for primary biliary cirrhosis: a meta-analysis. Lancet 1999; 354: 1053-1060.
-
(1999)
Lancet
, vol.354
, pp. 1053-1060
-
-
Goulis, J.1
Leandro, G.2
Burroughs, A.K.3
-
3
-
-
14944361288
-
The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis
-
Corpechot C, Carrat F, Bahr A, Chretien Y, Poupon RE, Poupon R. The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis. Gastroenterology 2005; 128: 297-303.
-
(2005)
Gastroenterology
, vol.128
, pp. 297-303
-
-
Corpechot, C.1
Carrat, F.2
Bahr, A.3
Chretien, Y.4
Poupon, R.E.5
Poupon, R.6
-
4
-
-
0025247125
-
Hepatic injury induced by bile salts: Correlation between biochemical and morphological events
-
Schmucker DL, Ohta M, Kanai S, Sato Y, Kitani K. Hepatic injury induced by bile salts: correlation between biochemical and morphological events. Hepatology 1990; 12: 1216-1221.
-
(1990)
Hepatology
, vol.12
, pp. 1216-1221
-
-
Schmucker, D.L.1
Ohta, M.2
Kanai, S.3
Sato, Y.4
Kitani, K.5
-
5
-
-
0033172845
-
Mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseases
-
Trauner M, Graziadei IW. Mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseases. Aliment Pharmacol Ther 1999; 13: 979-996.
-
(1999)
Aliment Pharmacol Ther
, vol.13
, pp. 979-996
-
-
Trauner, M.1
Graziadei, I.W.2
-
6
-
-
0034945397
-
Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'
-
Lazaridis KN, Gores GJ, Lindor KD. Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'. J Hepatol 2001; 35: 134-146.
-
(2001)
J Hepatol
, vol.35
, pp. 134-146
-
-
Lazaridis, K.N.1
Gores, G.J.2
Lindor, K.D.3
-
7
-
-
0025202952
-
Effect of chronic administration of ursodeoxycholic acid on the ileal absorption of endogenous bile acids in man
-
Marteau P, Chazouilleres O, Myara A, Jian R, Rambaud JC, Poupon R. Effect of chronic administration of ursodeoxycholic acid on the ileal absorption of endogenous bile acids in man. Hepatology 1990; 12: 1206-1208.
-
(1990)
Hepatology
, vol.12
, pp. 1206-1208
-
-
Marteau, P.1
Chazouilleres, O.2
Myara, A.3
Jian, R.4
Rambaud, J.C.5
Poupon, R.6
-
8
-
-
0033985520
-
Mitochondrial membrane perturbations in cholestasis
-
Rodrigues CM, Steer CJ. Mitochondrial membrane perturbations in cholestasis. J Hepatol 2000; 32: 135-141.
-
(2000)
J Hepatol
, vol.32
, pp. 135-141
-
-
Rodrigues, C.M.1
Steer, C.J.2
-
9
-
-
0025098908
-
Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: Effect of ursodeoxycholic acid
-
Calmus Y, Gane P, Rouger P, Poupon R. Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: effect of ursodeoxycholic acid. Hepatology 1990; 11: 12-15.
-
(1990)
Hepatology
, vol.11
, pp. 12-15
-
-
Calmus, Y.1
Gane, P.2
Rouger, P.3
Poupon, R.4
-
10
-
-
0035069055
-
Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids
-
Sokol RJ, Straka MS, Dahl R et al. Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids. Pediatr Res 2001; 49: 519-531.
-
(2001)
Pediatr Res
, vol.49
, pp. 519-531
-
-
Sokol, R.J.1
Straka, M.S.2
Dahl, R.3
-
11
-
-
0035129976
-
Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition
-
Yerushalmi B, Dahl R, Devereaux MW, Gumpricht E, Sokol RJ. Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. Hepatology 2001; 33: 616-626.
-
(2001)
Hepatology
, vol.33
, pp. 616-626
-
-
Yerushalmi, B.1
Dahl, R.2
Devereaux, M.W.3
Gumpricht, E.4
Sokol, R.J.5
-
12
-
-
0029825946
-
Effect of deoxycholic acid and ursodeoxycholic acid on lipid peroxidation in cultured macrophages
-
Ljubuncic P, Fuhrman B, Oiknine J, Aviram M, Bomzon A. Effect of deoxycholic acid and ursodeoxycholic acid on lipid peroxidation in cultured macrophages. Gut 1996; 39: 475-478.
-
(1996)
Gut
, vol.39
, pp. 475-478
-
-
Ljubuncic, P.1
Fuhrman, B.2
Oiknine, J.3
Aviram, M.4
Bomzon, A.5
-
13
-
-
0032124868
-
Effect of bile acids on lipid peroxidation: The role of iron
-
Sreejayan N, von Ritter C. Effect of bile acids on lipid peroxidation: the role of iron. Free Radic Biol Med 1998; 25: 50-56.
-
(1998)
Free Radic Biol Med
, vol.25
, pp. 50-56
-
-
Sreejayan, N.1
von Ritter, C.2
-
14
-
-
0036890346
-
Antioxidant properties of ursodeoxycholic acid
-
Lapenna D, Ciofani G, Festi D et al. Antioxidant properties of ursodeoxycholic acid. Biochem Pharmacol 2002; 64: 1661-1667.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 1661-1667
-
-
Lapenna, D.1
Ciofani, G.2
Festi, D.3
-
15
-
-
0034869459
-
Oxidative stress-related molecules and liver fibrosis
-
Parola M, Robino G. Oxidative stress-related molecules and liver fibrosis. J Hepatol 2001; 35: 297-306.
-
(2001)
J Hepatol
, vol.35
, pp. 297-306
-
-
Parola, M.1
Robino, G.2
-
16
-
-
0036623357
-
Oxidative stress in chronic hepatitis C: Not just a feature of late stage disease
-
Jain SK, Pemberton PW, Smith A et al. Oxidative stress in chronic hepatitis C: not just a feature of late stage disease. J Hepatol 2002; 36: 805-811.
-
(2002)
J Hepatol
, vol.36
, pp. 805-811
-
-
Jain, S.K.1
Pemberton, P.W.2
Smith, A.3
-
17
-
-
3242812768
-
Oxidant stress in type I autoimmune hepatitis: The link between necroinflammation and fibrogenesis?
-
Pemberton PW, Aboutwerat A, Smith A, Burrows PC, McMahon RF, Warnes TW. Oxidant stress in type I autoimmune hepatitis: the link between necroinflammation and fibrogenesis? Biochim Biophys Acta 2004; 1689: 182-189.
-
(2004)
Biochim Biophys Acta
, vol.1689
, pp. 182-189
-
-
Pemberton, P.W.1
Aboutwerat, A.2
Smith, A.3
Burrows, P.C.4
McMahon, R.F.5
Warnes, T.W.6
-
18
-
-
24744456677
-
Non-invasive monitoring of oxidant stress in alcoholic liver disease
-
Pemberton PW, Smith A, Warnes TW. Non-invasive monitoring of oxidant stress in alcoholic liver disease. Scand J Gastroenterol 2005; 40: 1102-1108.
-
(2005)
Scand J Gastroenterol
, vol.40
, pp. 1102-1108
-
-
Pemberton, P.W.1
Smith, A.2
Warnes, T.W.3
-
19
-
-
0037456669
-
Oxidant stress is a significant feature of primary biliary cirrhosis
-
Aboutwerat A, Pemberton PW, Smith A et al. Oxidant stress is a significant feature of primary biliary cirrhosis. Biochim Biophys Acta 2003; 1637: 142-150.
-
(2003)
Biochim Biophys Acta
, vol.1637
, pp. 142-150
-
-
Aboutwerat, A.1
Pemberton, P.W.2
Smith, A.3
-
20
-
-
0023262886
-
A controlled trial of colchicine in primary biliary cirrhosis
-
Warnes JW, Smith A, Lee FI, Haboubi NY, Johnson PJ, Hunt L. A controlled trial of colchicine in primary biliary cirrhosis. J Hepatol 1987; 5: 1-7.
-
(1987)
J Hepatol
, vol.5
, pp. 1-7
-
-
Warnes, J.W.1
Smith, A.2
Lee, F.I.3
Haboubi, N.Y.4
Johnson, P.J.5
Hunt, L.6
-
21
-
-
0018380993
-
Serum bilirubin: A prognostic factor in primary biliary cirrhosis
-
Shapiro JM, Smith H, Schaffner F. Serum bilirubin: a prognostic factor in primary biliary cirrhosis. Gut 1979; 20: 137-140.
-
(1979)
Gut
, vol.20
, pp. 137-140
-
-
Shapiro, J.M.1
Smith, H.2
Schaffner, F.3
-
22
-
-
0015854966
-
Transection of the oesophagus for bleeding oesophageal varices
-
Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973; 60: 646-649.
-
(1973)
Br J Surg
, vol.60
, pp. 646-649
-
-
Pugh, R.N.1
Murray-Lyon, I.M.2
Dawson, J.L.3
Pietroni, M.C.4
Williams, R.5
-
23
-
-
0026701545
-
Enhanced chemiluminescent assay for antioxidant capacity in biological fluids
-
Whitehead TP, Thorpe GH, Maxwell SR. Enhanced chemiluminescent assay for antioxidant capacity in biological fluids. Anal Chim Acta 1992; 266: 265-277.
-
(1992)
Anal Chim Acta
, vol.266
, pp. 265-277
-
-
Whitehead, T.P.1
Thorpe, G.H.2
Maxwell, S.R.3
-
24
-
-
0021288857
-
Glutathione disulfide (GSSG) efflux from cells and tissues
-
Sies H, Akerboom TP. Glutathione disulfide (GSSG) efflux from cells and tissues. Methods Enzymol 1984; 105: 445-451.
-
(1984)
Methods Enzymol
, vol.105
, pp. 445-451
-
-
Sies, H.1
Akerboom, T.P.2
-
25
-
-
0023939979
-
Type III procollagen peptide: A marker of disease activity and prognosis in primary biliary cirrhosis
-
Babbs C, Smith A, Hunt LP, Rowan BP, Haboubi NY, Warnes TW. Type III procollagen peptide: a marker of disease activity and prognosis in primary biliary cirrhosis. Lancet 1988; 1: 1021-1024.
-
(1988)
Lancet
, vol.1
, pp. 1021-1024
-
-
Babbs, C.1
Smith, A.2
Hunt, L.P.3
Rowan, B.P.4
Haboubi, N.Y.5
Warnes, T.W.6
-
26
-
-
12144286014
-
Ursodeoxycholic acid protects against secondary biliary cirrhosis in rats by preventing mitochondrial oxidative stress
-
Serviddio G, Pereda J, Pallardo FV et al. Ursodeoxycholic acid protects against secondary biliary cirrhosis in rats by preventing mitochondrial oxidative stress. Hepatology 2004; 39: 711-720.
-
(2004)
Hepatology
, vol.39
, pp. 711-720
-
-
Serviddio, G.1
Pereda, J.2
Pallardo, F.V.3
-
27
-
-
0344867846
-
S-adenosylmethionine in alcoholic liver cirrhosis: A randomized, placebo-controlled, double-blind, multicenter clinical trial
-
Mato JM, Camara J, Fernandez de Paz J et al. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J Hepatol 1999; 30: 1081-1089.
-
(1999)
J Hepatol
, vol.30
, pp. 1081-1089
-
-
Mato, J.M.1
Camara, J.2
Fernandez de Paz, J.3
-
28
-
-
0019740345
-
Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples
-
Akerboom TP, Sies H. Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. Methods Enzymol 1981; 77: 373-382.
-
(1981)
Methods Enzymol
, vol.77
, pp. 373-382
-
-
Akerboom, T.P.1
Sies, H.2
-
29
-
-
0033067354
-
Regulation of hepatic glutathione synthesis: Current concepts and controversies
-
Lu SC. Regulation of hepatic glutathione synthesis: current concepts and controversies. FASEB J 1999; 13: 1169-1183.
-
(1999)
FASEB J
, vol.13
, pp. 1169-1183
-
-
Lu, S.C.1
-
30
-
-
0036109728
-
Effect of ursodeoxycholic acid on methionine adenyltransferase activity and hepatic glutathione metabolism in rats
-
Rodriguez-Ortigosa CM, Cincu RN, Sanz S, Ruiz F, Quiroga J, Prieto J. Effect of ursodeoxycholic acid on methionine adenyltransferase activity and hepatic glutathione metabolism in rats. Gut 2002; 50: 701-7060
-
(2002)
Gut
, vol.50
, pp. 701-7060
-
-
Rodriguez-Ortigosa, C.M.1
Cincu, R.N.2
Sanz, S.3
Ruiz, F.4
Quiroga, J.5
Prieto, J.6
-
31
-
-
0033600824
-
Ursodeoxycholic acid protects hepatocytes against oxidative injury via induction of antioxidants
-
Mitsuyoshi H, Nakashima T, Sumida Y et al. Ursodeoxycholic acid protects hepatocytes against oxidative injury via induction of antioxidants. Biochem Biophys Res Commun 1999; 263: 537-542.
-
(1999)
Biochem Biophys Res Commun
, vol.263
, pp. 537-542
-
-
Mitsuyoshi, H.1
Nakashima, T.2
Sumida, Y.3
-
32
-
-
0021165717
-
Mechanism of biliary secretion of membranous enzymes: Bile acids are important factors for biliary occurrence of gamma-glutamyltransferase and other hydrolases
-
Hirata E, Inoue M, Morino Y. Mechanism of biliary secretion of membranous enzymes: bile acids are important factors for biliary occurrence of gamma-glutamyltransferase and other hydrolases. J Biochem (Tokyo) 1984; 96: 289-297.
-
(1984)
J Biochem (Tokyo)
, vol.96
, pp. 289-297
-
-
Hirata, E.1
Inoue, M.2
Morino, Y.3
-
33
-
-
0343963252
-
Chemical and biological activity of free radical 'scavengers' in allergic disease
-
Mates JM, Perez-Gomez C, Blanca M. Chemical and biological activity of free radical 'scavengers' in allergic disease. Clin Chim Acta 2000; 296: 1-15.
-
(2000)
Clin Chim Acta
, vol.296
, pp. 1-15
-
-
Mates, J.M.1
Perez-Gomez, C.2
Blanca, M.3
-
34
-
-
33646932475
-
The generation and actions of isoprostanes
-
Roberts U, Morrow JD. The generation and actions of isoprostanes. Biochim Biophys Acta 1997; 1345: 121-135.
-
(1997)
Biochim Biophys Acta
, vol.1345
, pp. 121-135
-
-
Roberts, U.1
Morrow, J.D.2
-
35
-
-
0032776363
-
Prognostic factors and long-term effects of ursodeoxycholic acid on liver biochemical parameters in patients with primary biliary cirrhosis
-
van Hoogstraten HJ, Hansen BE, van Buuren HR, ten Kate F, van Berge-Henegouwen GP, Schalm SW. Prognostic factors and long-term effects of ursodeoxycholic acid on liver biochemical parameters in patients with primary biliary cirrhosis. J Hepatol 1999; 31: 256-262.
-
(1999)
J Hepatol
, vol.31
, pp. 256-262
-
-
van Hoogstraten, H.J.1
Hansen, B.E.2
van Buuren, H.R.3
ten Kate, F.4
van Berge-Henegouwen, G.P.5
Schalm, S.W.6
-
36
-
-
0033869778
-
Pathogenesis of liver fibrosis: Role of oxidative stress
-
Poli G. Pathogenesis of liver fibrosis: role of oxidative stress. Mol Aspects Med 2000; 21: 49-98.
-
(2000)
Mol Aspects Med
, vol.21
, pp. 49-98
-
-
Poli, G.1
-
37
-
-
0028838193
-
Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression
-
Lee KS, Buck M, Houglum K, Chojkier M. Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression. J Clin Invest 1995; 96: 2461-2468.
-
(1995)
J Clin Invest
, vol.96
, pp. 2461-2468
-
-
Lee, K.S.1
Buck, M.2
Houglum, K.3
Chojkier, M.4
-
39
-
-
0033658752
-
The effect of ursodeoxycholic acid therapy on liver fibrosis progression in primary biliary cirrhosis
-
Corpechot C, Carrat F, Bonnand AM, Poupon RE, Poupon R. The effect of ursodeoxycholic acid therapy on liver fibrosis progression in primary biliary cirrhosis. Hepatology 2000; 32: 1196-1199.
-
(2000)
Hepatology
, vol.32
, pp. 1196-1199
-
-
Corpechot, C.1
Carrat, F.2
Bonnand, A.M.3
Poupon, R.E.4
Poupon, R.5
|