Evidence against a role for ovarian hormones in the regulation of blood flow

Fertility and Sterility

Volumn 86, Issue 2, 2006, Pages 440-447

  Cooper, Brian C ^a   Sites, Cynthia K ^a   Fairhurst, Penny A ^a   Toth, Michael J ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

estradiol; gonadotropin releasing hormone agonist; Ovarian hormone deficiency; progesterone

Indexed keywords

ESTROGEN; GONADORELIN AGONIST; INSULIN;

ADULT; AMINOACIDEMIA; ARTICLE; BLOOD FLOW; BLOOD VESSEL FUNCTION; CLINICAL RESEARCH; CONTROLLED STUDY; ESTROGEN ACTIVITY; ESTROGEN DEFICIENCY; FEMALE; FOLLICULAR PHASE; HUMAN; HYPERINSULINEMIA; INSULIN INFUSION; LUTEAL PHASE; MENSTRUAL CYCLE; NORMAL HUMAN; OVARY BLOOD FLOW; PREMENOPAUSE; PRIORITY JOURNAL; RANDOMIZATION; VEIN OCCLUSION PLETHYSMOGRAPHY;

EID: 33746330781     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2006.01.017     Document Type: Article

References (48)

1. Jensen J., and Nilas L. Christiansen C. Influence of menopause on serum lipids and lipoproteins. Maturitas 12 (1990) 321-331
2. Lewis S.J. Cardiovascular disease in postmenopauseal women. myths and reality. Am J Cardiol 89 (2002) 5E-11E
3. Carr M.C. The emergence of the metabolic syndrome with menopause. J Clin Endocrinol Metab 88 (2003) 2404-2411
4. Wu S.I., Chou P., and Tsai S.T. The impact of years since menopause on the development of impaired glucose tolerance. J Clin Epidemiol 54 (2001) 117-120
5. Davignon J., and Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation 109 (2004) 27-32
6. Baron A.D., Steinberg H.O., Chaker H., Leaming R., Johnson A., and Brechtel G. Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans. J Clin Invest 96 (1995) 786-792
7. Baron A.D. Hemodynamic actions of insulin. Am J Physiol Endocrinol Metab 267 (1994) E187-E202
8. Meneilly G.S., Elliot T., Bryer-Ash M., and Floras J.S. Insulin-mediated increase in blood flow is impaired in the elderly. J Clin Endocrinol Metab 80 (1995) 1899-1903
9. Sanada M., Higashi Y., Nakagawa K., Kodama I., Tsuda M., Nagai N., et al. Comparison of forearm endothelial function between premenopausal and postmenopausal women with or without hypercholesterolemia. Maturitas 44 (2003) 307-315
10. Mercuro G., Longu G., Zoncu S., and Cherchi A. Impaired forearm blood flow and vasodilator reserve in healthy postmenopausal women. Am Heart J 137 (1999) 692-697
11. Sanada M., Higashi Y., Nakagawa K., Sasaki S., Kodama I., Sakashita T., et al. Estrogen replacement therapy in postmenopausal women augments reactive hyperemia in the forearm by reducing angiotensin converting enzyme activity. Atherosclerosis 158 (2001) 391-397
12. Sanada M., Higashi Y., Nakagawa K., Sasaki S., Kodama I., Tsuda M., et al. Relationship between the angiotensin-converting enzyme genotype and the forearm vasodilator response to estrogen replacement therapy in postmenopausal women. J Am Coll Cardiol 37 (2001) 1529-1535
13. Higashi Y., Sanada M., Sasaki S., Nakagawa K., Goto C., Matsuura H., et al. Effect of estrogen replacement therapy on endothelial function in peripheral resistance arteries in normotensive and hypertensive postmenopausal women. Hypertension 37 (2001) 651-657
14. Toth M.J., Tchernof A., Sites C.K., and Poehlman E.T. Effect of menopausal status on body composition and abdominal fat distribution. Int J Obestiy 24 (2000) 226-231
15. Suh H.S., Park Y.W., Kang J.H., Lee S.H., Lee H.S., and Shim K.W. Vascular endothelial dysfunction tested by blunted response to endothelium-dependent vasodilation by salbutamol and its related factors in uncomplicated pre-menopausal obese women. Int J Obesity 29 (2005) 217-222
16. Lamarche B. Abdominal obesity and its metabolic complications. implications for the risk of ischaemic heart disease. Coronary Artery Dis 9 (1998) 473-481
17. Bowyer L., Brown M.A., and Jones M. Vascular reactivity in men and women of reproductive age. Am J Obstet Gynecol 185 (2001) 88-96
18. Chan N.N., MacAllister R.J., Colhoun H.M., Vallance P., and Hingorani A.D. Changes in endothelium-dependent vasodilatation and the β-adrenergic responses in resistance vessels during the menstrual cycle in healthy women. J Clin Endocrinol Metab 86 (2001) 2499-2504
19. Steinberg H.O., Brechtel G., Johnson A., Fineberg N., and Baron A.D. Insulin-mediated skeletal muscle vasodiation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Invest 94 (1994) 1172-1179
20. Hisamoto K., and Bender J.R. Vascular cell signaling by membrane estrogen receptors. Steroids 70 (2005) 382-387
21. Toth M.J., Tcernof A., Rosen C.J., Matthews D.E., and Poehlman E.T. Regulation of protein metabolism in middle-aged, premenopausal women. roles of adiposity and estradiol. J Clin Endocrinol Metab 85 (2001) 1382-1387
22. Castellino P., Luzi L., Simonson D.C., Haymond M., and DeFronzo R.A. Effect of insulin and plasma amino acid concentrations on leucine metabolism in man. Role of substrate availability on estimates of whole body protein synthesis. J Clin Invest 80 (1987) 1784-1793
23. Vermeulen A., Verdonck L., and Kaufman H.M. A critical evaluation of simple methods for estimation of free testosterone in serum. J Clin Endocrinol Metab 84 (1999) 3666-3672
24. Sodergard R., Backstrom T., Shanbhag V., and Carstensen H. Calculation of free and bound fractions of testosterone and estradiol-17beta to human plasma protein at body temperature. J Steroid Biochem 26 (1982) 801-810
25. Bernstein I.M., Ziegler W.F., Leavitt T., and Badger G.J. Uterine artery hemodynamic adaptations through the menstrual cycle into early pregnancy. Obstet Gynecol 99 (2002) 620-624
26. Lehtovirta P. Forearm blood flow in the normal menstrual cycle. Int J Gynaecol Obstet 20 (1982) 223-226
27. Bartelink M.L., Wollersheim H., Theeuwes A., van Duren D., and Thien T.H. Changes in skin blood flow during the menstrual cycle. the influence of the menstrual cycle on the peripheral circulation in healthy female volunteers. Clin Sci 78 (1990) 527-532
28. Kawano H., Motoyama T., Kugiyama K., Hirashima O., Ohgushi M., Yoshimura M., et al. Menstrual cycle variation of the endothelium-dependent vasodilation of the brachial artery. possible role of estrogen and nitric oxide. Proc Assoc Am Physicians 108 (1996) 473-480
29. Bungum L., Kvernebo K., Øian P., and Maltau J.M. Laser Doppler-recorded reactive hyperaemia in the forearm skin during the menstrual cycle. Br J Obstet Gynecol 103 (1996) 70-75
30. Eskurza I., Seals D.R., DeSouza C.A., and Tanaka H. Pharmacologic versus flow-mediated assessments of peripheral vascular endothelial vasodilatory function in humans. Am J Cardiol 88 (2001) 1067-1069
31. Jayachandran M., Mukherjee R., Steinkamp T., LaBreche P., Bracamonte M.P., Okano H., et al. Differential effects of 17beta-estradiol, conjugated equine estrogen, and raloxifene on mRNA expression, aggregation, and secretion in platelets. Am J Physiol 288 (2005) H2355-H2362
32. Hulley S., Grady D., Bush T., Furberg C., Herrington D., Riggs B., and Vittinghoff E. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA 280 (1998) 605-613
33. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women. principal results from the Women's Health Initiative randomized controlled trial. JAMA 288 (2002) 321-333
34. Women's Health Initiative Steering Committee. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy. the Women's Health Initiative randomized controlled trial. JAMA 291 (2004) 1701-1712
35. Ohmichi M., Kanda Y., Hisamoto K., Morishige K.-I., Takahashi K., Sawada K., et al. Rapid changes of flow-mediated dilatation after surgical menopause. Maturitas 44 (2003) 125-131
36. Mercuro G., Zoncu S., Saiu F., Mascia M., Melis G.B., and Rosano G.M.C. Menopause induced by oophorectomy reveals a role of ovarian estrogen on the maintenance of pressure homeostasis. Maturitas 47 (2004) 131-138
37. Norjavaara E., Olofsson J., Gåfvels M., and Selstam G. Redistribution of ovarian blood flow after injection of human chorionic gonadotropin and luteinizing hormone in the adult pseudopregnant rat. J Clin Endocrinol Metab 120 (1987) 107-114
38. Janson P.O. Effects of the luteinizing hormone on blood flow in the follicular rabbit ovary, as measured by radioactive microspheres. Acta Endocrinologica 79 (1975) 122-133
39. Bergh A., Damber J.-E., Lieu L., and Widmark A. Does follicle-stimulating hormone or pregnant mare serum gonadotrophin influence testicular blood flow in rats?. Int J Andrology 15 (1992) 365-371
40. Hughs C.L., Wall L.L., and Creasman W.T. Reproductive hormone levels in gynecologic oncology patients undergoing surgical castration after spontaneous menopause. Gynecol Oncol 40 (1991) 42-45
41. Laughlin G.A., Barrett-Connor E., Kritz-Silverstein D., and von Muhlen D. Hysterectomy, oophorectomy, and endogenous sex hormone levels in older women. the Rancho Bernardo Study. J Clin Endocrinol Metab 85 (2000) 645-651
42. Liu P.Y., Death A.K., and Handelsman D.J. Androgens and cardiovascular disease. Endocrine Rev 24 (2003) 313-340
43. Chou T.M., Sudhir K., Hutchison S.J., Ko E., Amidon T.M., Collins P.J., and Chatterjee K. Testosterone induces dilation of canine coronary conductance and resistance arteries in vivo. Circulation 94 (1996) 2614-2619
44. Ong P.J.L., Patrizi G., Chong W.C.F., Webb C.M., Hayward C.S., and Collins P. Testosterone enhances flow-mediated brachial artery reactivity in men with coronary artery disease. Am J Cardiol 85 (2000) 269-272
45. Webb C.M., McNeill J.G., Hayward C.S., de Zeigler D., and Collins P. Effects of testosterone on coronary vasomotor regulation in men with coronary heart disease. Circulation 100 (1999) 1690-1696
46. Worboys S., Kotsopoulos D., Teede H., McGrath B., and Davis S.R. Evidence that parenteral testosterone therapy may improve endothelium-dependent and -independent vasodilation in postmenopausal women already receiving estrogen. J Clin Endocrinol Metab 86 (2001) 158-161
47. Zeiher A.M., Drexler H., Wollschlager H., and Just H. Modulation of coronary vasomotor tone in humans. progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circ 83 (1991) 391-401
48. Herrington D.M., Kesler K., Reiber J.C., Davis W., Brown W.V., Helms R., et al. Arterial compliance adds to conventional risk factors for prediction of angiographic coronary artery disease. Am Heart J 146 (2003) 662-667