Eosinophilic inflammation, remodeling of lower airway, bronchial responsiveness and cough reflex sensitivity in non-asthmatic subjects with nasal allergy

International Archives of Allergy and Immunology

Volumn 140, Issue 4, 2006, Pages 327-333

  Hara, Johsuke ^a   Fujimura, Masaki ^a   Myou, Shigeharu ^a   Furusho, Shiho ^a   Abo, Miki ^a   Oribe, Yoshitaka ^a   Ohkura, Noriyuki ^a   Herai, Yoriko ^a   Sone, Takashi ^a   Waseda, Yuko ^a   Yasui, Masahide ^a   Kasahara, Kazuo ^a  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

Author keywords

Bronchial responsiveness; Cough reflex sensitivity; Eosinophilic inflammation; Lower airway remodeling; Nasal allergy

Indexed keywords

CAPSAICIN; METHACHOLINE; SODIUM CHLORIDE;

ADULT; ARTICLE; BRONCHUS REACTIVITY; CONTROLLED STUDY; COUGHING; EOSINOPHIL COUNT; FEMALE; FORCED EXPIRATORY VOLUME; HAY FEVER; HUMAN; JAPANESE CEDAR; LOWER RESPIRATORY TRACT; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; NOSE ALLERGY; PERENNIAL RHINITIS; POLLEN ALLERGY; PRIORITY JOURNAL; PROVOCATION TEST; REFLEX; RESPIRATORY TRACT INFLAMMATION; SPUTUM ANALYSIS;

ADULT; BRONCHIAL PROVOCATION TESTS; BRONCHOCONSTRICTOR AGENTS; CAPSAICIN; COUGH; EOSINOPHILS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; MAXIMAL MIDEXPIRATORY FLOW RATE; METHACHOLINE CHLORIDE; PNEUMONIA; PULMONARY VENTILATION; REFLEX; RESPIRATORY FUNCTION TESTS; RHINITIS, ALLERGIC, PERENNIAL; RHINITIS, ALLERGIC, SEASONAL; SALINE SOLUTION, HYPERTONIC; SPUTUM; VITAL CAPACITY;

EID: 33746329281     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000093711     Document Type: Article

References (26)

1. Corren J: Allergic rhinitis and asthma: how important is the link? J Allergy Clin Immunol 1997;99:S781-S786.
2. Guerra S, Sherrill DL, Martinez FD, Barbee RA: Rhinitis as an independent risk factor for adult-onset asthma. J Allergy Clin Immunol 2002;109:419-425.
3. Braunstahl GJ, Fokkens WJ, Overbeek SE, Kleinjan A, Hoogsteden HC, Prins JB: Mucosal and systemic inflammatory changes in allergic rhinitis and asthma: a comparison between upper and lower airways. Clin Exp Allergy 2003;33:579-587.
4. Greiff L, Andersson M, Svensson C, Linden M, Wollmer P, Persson CG: Demonstration of bronchial eosinophil activity in seasonal allergic rhinitis by induced plasma exudation combined with induced sputum. Thorax 1999;54:33-36.
5. Polosa R, Ciamarra I, Mangano G, Prosperini G, Pistorio MP, Vancheri C, et al: Bronchial hyperresponsiveness and airway inflammation markers in nonasthmatics with allergic rhinitis. Eur Respir J 2000;15:30-35.
6. Stevens WJ, Vermeire PA: Bronchial responsiveness to histamine and allergen in patients with asthma, rhinitis, cough. Eur J Respir Dis 1980;61:203-212.
7. Bruce CA, Rosenthal RR, Lichtenstein LM, Norman PS: Quantitative inhalation bronchial challenge in ragweed hay fever patients: a comparison with ragweed-allergic asthmatics. J Allergy Clin Immunol 1975;56:331-337.
8. Nakamura A, Asai T, Yoshida K, Baba K, Nakae K: [Allergic rhinitis epidemiology in Japan]. Nippon Jibiinkoka Gakkai Kaiho 2002;105:215-224.
9. Naito K, Iwata S, Yokoyama N: Laryngeal symptoms in patients exposed to Japanese cedar pollen: allergic reactions and environmental pollution. Eur Arch Otorhinolaryngol 1999;256:209-211.
10. Global Initiative for Asthma: Global Strategy for Asthma Management and Prevention. Bethesda, National Institutes of Health, 2002, NIH publ 02-3659.
11. Fujimura M, Sakamoto S, Kamio Y, Matsuda T: Effects of methacholine induced bronchoconstriction and procaterol induced bronchodilation on cough receptor sensitivity to inhaled capsaicin and tartaric acid. Thorax 1992;47:441-445.
12. Makino S, Kobayashi S, Miyamoto T, Shida T, Takahashi S: Standard for allergen bronchial provocation tests in asthma and hypersensitivity pneumonitis. Arerugi 1982;31:1074-1076.
13. Fujimura M, Songur N, Kamio Y, Matsuda T: Detection of eosinophils in hypertonic saline-induced sputum in patients with chronic non-productive cough. J Asthma 1997;34:119-126.
14. Foresi A, Leone C, Pelucchi A, Mastropasqua B, Chetta A, D'Ippolito R, et al: Eosinophils, mast cells, and basophils in induced sputum from patients with seasonal allergic rhinitis and perennial asthma: relationship to methacholine responsiveness. J Allergy Clin Immunol 1997;100:58-64.
15. Gibson PG, Fujimura M, Niimi A: Eosinophilic bronchitis: clinical manifestations and implications for treatment. Thorax 2002;57:178-182.
16. Boulet LP, Laviolette M, Turcotte H, Cartier A, Dugas M, Malo JL, et al: Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine. Chest 1997;112:45-52.
17. Chakir J, Laviolette M, Boutet M, Laliberte R, Dube J, Boulet LP: Lower airways remodeling in nonasthmatic subjects with allergic rhinitis. Lab Invest 1996;75:735-744.
18. Ciprandi G, Cirillo I, Tosca MA, Vizzaccaro A: Bronchial hyperreactivity and spirometric impairment in patients with perennial allergic rhinitis. Int Arch Allergy Immunol 2004;133:14-18.
19. Bjermer L: History and future perspectives of treating asthma as a systemic and small airways disease. Respir Med 2001;95:703-719.
20. Boulet LP, Turcotte H, Carrier G, Boutet M, Laviolette M: Increased maximal airway response to methacholine during seasonal allergic rhinitis in nonasthmatic subjects: relationships with airway wall thickness and inflammation. Eur Respir J 1995;8:913-921.
21. Alvarez MJ, Olaguibel JM, Garcia BE, Rodriquez A, Tabar AI, Urbiola E: Airway inflammation in asthma and perennial allergic rhinitis: relationship with nonspecific bronchial responsiveness and maximal airway narrowing. Allergy 2000;55:355-362.
22. Lim S, Jatakanon A, John M, Gilbey T, O'Connor BJ, Chung KF, et al: Effect of inhaled budesonide on lung function and airway inflammation. Assessment by various inflammatory markers in mild asthma. Am J Respir Crit Care Med 1999;159:22-30.
23. Jatakanon A, Lim S, Kharitonov SA, Chung KF, Barnes PJ: Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax 1998;53:91-95.
24. Jang AS, Choi IS, Lee S, Seo JP, Yang SW, Park KO, et al: Nitric oxide metabolites in induced sputum: a marker of airway inflammation in asthmatic subjects. Clin Exp Allergy 1999;29:1136-1142.
25. Fujimura M, Sakamoto S, Matsuda T: Bronchodilator-resistive cough in atopic patients: bronchial reversibility and hyperresponsiveness. Intern Med 1992;31:447-452.
26. Minoguchi H, Minoguchi K, Tanaka A, Matsuo H, Kihara N, Adachi M: Cough receptor sensitivity to capsaicin does not change after allergen bronchoprovocation in allergic asthma. Thorax 2003;58:19-22.