Hypothalamic hamartomas - Clinical, neuropathological and surgical aspects

Child's Nervous System

Volumn 22, Issue 8, 2006, Pages 867-873

  Maixner, Wirginia ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

Epilepsy surgery; Gelastic seizures; Hypothalamic Hamartoma

Indexed keywords

ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN SURGERY; CLINICAL FEATURE; ENDOSCOPIC SURGERY; EPILEPTOGENESIS; GENERALIZED EPILEPSY; HAMARTOMA; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; NEUROIMAGING; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RADIOSURGERY; SURGICAL APPROACH; SURGICAL RISK; SURGICAL TECHNIQUE; TREATMENT INDICATION; TREATMENT PLANNING;

ELECTROPHYSIOLOGY; HAMARTOMA; HUMANS; HYPOTHALAMIC DISEASES; MAGNETIC RESONANCE IMAGING; NERVE TISSUE PROTEINS;

EID: 33746305905     PISSN: 02567040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00381-006-0129-0     Document Type: Article

References (41)

1. Andermann F, Arzimanoglou A, Berkovic SF (2003) Hypothalamic hamartoma and epilepsy: The pathway of discovery. Epileptic Disord 5:173-175
2. Arita K, Ikawa F, Kurisu K, Sumida M, Harada K, Uozumi T, Monden S, Yoshida J, Nishi Y (1999) The relationship between magnetic resonance imaging findings and clinical manifestations of hypothalamic hamartoma. J Neurosurg 91:212-220
3. Arroyo S, Lesser RP, Gordon B, Uematsu S, Hart J, Schwerdt P, Andreasson K, Fisher RS (1993) Mirth, laughter and gelastic seizures. Brain 116(Pt 4):757-780
4. Arzimanoglou AA, Hirsch E, Aicardi J (2003) Hypothalamic hamartoma and epilepsy in children: Illustrative cases of possible evolutions. Epileptic Disord 5:187-199
5. Berkovic SF, Andermann F, Melanson D, Ethier RE, Feindel W, Gloor P (1988) Hypothalamic hamartomas and ictal laughter: Evolution of a characteristic epileptic syndrome and diagnostic value of magnetic resonance imaging. Ann Neurol 23:429-439
6. Berkovic SF, Kuzniecky RI, Andermann F (1997) Human epileptogenesis and hypothalamic hamartomas: New lessons from an experiment of nature. Epilepsia 38:1-3
7. Boudreau EA, Liow K, Frattali CM, Wiggs E, Turner JT, Feuillan P, Sato S, Patsalides A, Patronas N, Biesecker LG, Theodore WH (2005) Hypothalamic hamartomas and seizures: Distinct natural history of isolated and Pallister-Hall syndrome cases. Epilepsia 46:42-47
8. Cascino GD, Andermann F, Berkovic SF, Kuzniecky RI, Sharbrough FW, Keene DL, Bladin PF, Kelly PJ, Olivier A, Feindel W (1993) Gelastic seizures and hypothalamic hamartomas: Evaluation of patients undergoing chronic intracranial EEG monitoring and outcome of surgical treatment. Neurology 43:747-750
9. Choi JU, Yang KH, Kim TG, Chang JH, Chang JW, Lee BI, Kim DS (2004) Endoscopic disconnection for hypothalamic hamartoma with intractable seizure. Report of four cases. J Neurosurg 100:506-511
10. Coulter D (1997) Thalamocortical anatomy and physiology. In: Engel J, Pedley T (eds) Epilepsy: A comprehensive textbook. Lippincott-Raven, Philadelphia, pp 341-351
11. Delalande O, Fohlen M (2003) Disconnecting surgical treatment of hypothalamic hamartoma in children and adults with refractory epilepsy and proposal of a new classification. Neurol Med Chir (Tokyo) 43:61-68
12. DiFazio MP, Davis RG (2000) Utility of early single photon emission computed tomography (SPECT) in neonatal gelastic epilepsy associated with hypothalamic hamartoma. J Child Neurol 15:414-417
13. Fohlen M, Lellouch A, Delalande O (2003) Hypothalamic hamartoma with refractory epilepsy: Surgical procedures and results in 18 patients. Epileptic Disord 5:267-273
14. Frattali CM, Liow K, Craig GH, Korenman LM, Makhlouf F, Sato S, Biesecker LG, Theodore WH (2001) Cognitive deficits in children with gelastic seizures and hypothalamic hamartoma. Neurology 57:43-46
15. Freeman JL, Harvey AS, Rosenfeld JV, Wrennall JA, Bailey CA, Berkovic SF (2003) Generalized epilepsy in hypothalamic hamartoma: Evolution and postoperative resolution. Neurology 60:762-767
16. Freeman JL, Coleman LT, Wellard RM, Kean MJ, Rosenfeld JV, Jackson GD, Berkovic SF, Harvey AS (2004) MR imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: Analysis of 72 cases. AJNR Am J Neuroradiol 25:450-462
17. Harvey AS, Freeman JL, Berkovic SF, Rosenfeld JV (2003) Transcallosal resection of hypothalamic hamartomas in patients with intractable epilepsy. Epileptic Disord 5:257-265
18. Iannetti P, Chessa L, Raucci U, Basile LA, Fantozzi LM, Bozzao L (1992) Gelastic epilepsy. A clinical contribution. Clin Pediatr (Phila) 31:467-470
19. Kahane P, Munari C, Minotti L (1997) The role of the hypothalamic hamartoma in the genesis of gelastic and dacrystic seizures. In: Tuxhorn I, Hothausen H, Boenigk K (eds) Paediatric epilepsy syndromes and their surgical treatment. John Libbey, London, pp 447-461
20. Kerrigan JF, Ng YT, Chung S, Rekate HL (2005) The hypothalamic hamartoma: A model of subcortical epileptogenesis and encephalopathy. Semin Pediatr Neurol 12:119-131
21. Kuzniecky R, Guthrie B, Mountz J, Bebin M, Faught E, Gilliam F, Liu HG (1997) Intrinsic epileptogenesis of hypothalamic hamartomas in gelastic epilepsy. Ann Neurol 42:60-67
22. Leal AJ, Moreira A, Robalo C, Ribeiro C (2003) Different electroclinical manifestations of the epilepsy associated with hamartomas connecting to the middle or posterior hypothalamus. Epilepsia 44:1191-1195
23. Machado HR, Hoffman HJ, Hwang PA (1991) Gelastic seizures treated by resection of a hypothalamic hamartoma. Childs Nerv Syst 7:462-465
24. Morrell F (1989) Varieties of human secondary epileptogenesis. J Clin Neurophysiol 6:227-275
25. Mullatti N (2003) Hypothalamic hamartoma in adults. Epileptic Disord 5:201-204
26. Mullatti N, Selway R, Nashef L, Elwes R, Honavar M, Chandler C, Morris R, Jarosz J, Buchanan C, Polkey C (2003) The clinical spectrum of epilepsy in children and adults with hypothalamic hamartoma. Epilepsia 44:1310-1319
27. Munari C, Kahane P, Francione S, Hoffmann D, Tassi L, Cusmai R, Vigevano F, Pasquier B, Betti OO (1995) Role of the hypothalamic hamartoma in the genesis of gelastic fits (a video-stereo-EEG study). Electroencephalogr Clin Neurophysiol 95:154-160
28. Murphy JV, Wheless JW, Schmoll CM (2000) Left vagal nerve stimulation in six patients with hypothalamic hamartomas. Pediatr Neurol 23:167-168
29. Ng YT, Kerrigan JF, Prenger EC, White WL, Rekate HL (2005) Successful resection of a hypothalamic hamartoma and a Rathke cleft cyst. Case report. J Neurosurg 102:78-80
30. Nishio S, Morioka T, Fukui M, Goto Y (1994) Surgical treatment of intractable seizures due to hypothalamic hamartoma. Epilepsia 35:514-519
31. Northfield DW, Russell DS (1967) Pubertas praecox due to hypothalamic hamartoma: Report of two cases surviving surgical removal of the tumour. J Neurol Neurosurg Psychiatry 30:166-173
32. Paillas J, Roger J, Toga M (1969) Hamartoma of the hypothalamus. Clinical, radiological and histological study. Results of excision. Rev Neurol 120:177-194
33. Palmini A, Chandler C, Andermann F, Costa Da Costa J, Paglioli-Neto E, Polkey C, Rosenblatt B, Montes J, Martinez JV, Farmer JP, Sinclair B, Aronyk K, Paglioli E, Coutinho L, Raupp S, Portuguez M (2002) Resection of the lesion in patients with hypothalamic hamartomas and catastrophic epilepsy. Neurology 58:1338-1347
34. Palmini A, Paglioli-Neto E, Montes J, Farmer JP (2003) The treatment of patients with hypothalamic hamartomas, epilepsy and behavioural abnormalities: Facts and hypotheses. Epileptic Disord 5:249-255
35. Palmini A, Van Paesschen W, Dupont P, Van Laere K, Van Driel G (2005) Status gelasticus after temporal lobectomy: Ictal FDG-PET findings and the question of dual pathology involving hypothalamic hamartomas. Epilepsia 46:1313-1316
36. Polkey CE (2003) Resective surgery for hypothalamic hamartoma. Epileptic Disord 5:281-286
37. Sato M, Ushio Y, Arita N, Mogami H (1985) Hypothalamic hamartoma: Report of two cases. Neurosurgery 16:198-206
38. Striano S, Meo R, Bilo L, Cirillo S, Nocerino C, Ruosi P, Striano P, Estraneo A (1999) Gelastic epilepsy: Symptomatic and cryptogenic cases. Epilepsia 40:294-302
39. Tassinari C, Riguzzi P, Rizzi R (1997) Gelastic seizures. In: Tuxhorn I, Holthausen H, Boenigk K (eds) Paediatric epilepsy syndromes and their surgical management. John Libbey, London, pp 429-446
40. Weissenberger AA, Dell ML, Liow K, Theodore W, Frattali CM, Hernandez D, Zametkin AJ (2001) Aggression and psychiatric comorbidity in children with hypothalamic hamartomas and their unaffected siblings. J Am Acad Child Adolesc Psychiatry 40:696-703
41. Wu J, Xu L, Kim do Y, Rho JM, St John PA, Lue LF, Coons S, Ellsworth K, Nowak L, Johnson E, Rekate H, Kerrigan JF (2005) Electrophysiological properties of human hypothalamic hamartomas. Ann Neurol 58:371-382