Rskα-actin/hIGF-1 transgenic mice with increased IGF-I in skeletal muscle and blood: Impact on regeneration, denervation and muscular dystrophy

Growth Hormone and IGF Research

Volumn 16, Issue 3, 2006, Pages 157-173

  Shavlakadze, T ^a   Boswell, J M ^b   Burt, D W ^b   Asante, E A ^b   Tomas, F M ^c   Davies, M J ^a   White, J D ^a   Grounds, M D ^a   Goddard, C ^d  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c CSIRO   (Australia)

^d GroPep Ltd   (Australia)

Author keywords

Atrophy; Circulating IGF I; Growth; IGF I; mdx; Regeneration; Skeletal muscle; Transgenic mice

Indexed keywords

ALPHA ACTIN; MUSCLE PROTEIN; SOMATOMEDIN C; ACTIN;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BODY WEIGHT; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HETEROZYGOTE; IMMUNOASSAY; MALE; MOUSE; MOUSE STRAIN; MUSCLE ATROPHY; MUSCLE DENERVATION; MUSCLE HYPERTROPHY; MUSCLE NECROSIS; MUSCLE REGENERATION; MUSCULAR DYSTROPHY; NONHUMAN; PARACRINE SIGNALING; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIATIC NERVE; SLOW MUSCLE FIBER; STATISTICAL SIGNIFICANCE; STRAIN DIFFERENCE; TRANSGENE; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; CYTOLOGY; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; RAT; REGENERATION; SKELETAL MUSCLE; TRANSACTIVATION;

ACTINS; ANIMALS; BODY WEIGHT; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, TRANSGENIC; MUSCLE DENERVATION; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES; PROMOTER REGIONS (GENETICS); RATS; REGENERATION; TRANS-ACTIVATION (GENETICS);

EID: 33746277869     PISSN: 10966374     EISSN: 15322238     Source Type: Journal    
DOI: 10.1016/j.ghir.2005.11.003     Document Type: Article

References (51)

1. Sjogren K., Liu J.L., Blad K., et al. Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice. Proc. Natl. Acad. Sci. USA 96 (1999) 7088-7092
2. Yakar S., Liu J.L., Stannard B., et al. Normal growth and development in the absence of hepatic insulin-like growth factor I. Proc. Natl. Acad. Sci. USA 96 (1999) 7324-7329
3. D'Ercole A.J., and Calikoglu A.S. Editorial review: The case of local versus endocrine IGF-1 actions: the jury is still out. Growth Horm. IGF Res. 11 (2001) 261-265
4. Le Roith D., Scavo L., and Butler A. What is the role of circulating IGF-I?. Trends Endocrinol. Metab. 12 (2001) 48-52
5. Shavlakadze T., Winn N., Rosenthal N., and Grounds M.D. Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle. Growth. Horm. IGF Res. 15 (2005) 4-18
6. Hameed M., Orrell R.W., Cobbold M., Goldspink G., and Harridge S.D. Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise. J. Physiol. 547 (2003) 247-254
7. Hill M., and Goldspink G. Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage. J. Physiol. 549 (2003) 409-418
8. Coleman M.E., DeMayo F., Yin K.C., et al. Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. J. Biol. Chem. 270 (1995) 12109-12116
9. Musaro A., McCullagh K., Paul A., et al. Localized IGF-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat. Genet. 27 (2001) 195-200
10. Fiorotto M.L., Schwartz R.J., and Delaughter M.C. Persistent IGF-I overexpression in skeletal muscle transiently enhances DNA accretion and growth. Faseb J. 17 (2003) 59-60
11. Reiss K., Cheng W., Ferber A., et al. Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice. Proc. Natl. Acad. Sci. USA 93 (1996) 8630-8635
12. Wang J., Niu W., Nikiforov Y., et al. Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice. J. Clin. Invest. 100 (1997) 1425-1439
13. Mathews L., Hammer R., Behringer R., et al. Growth enhancement of transgenic mice expressing human insulin-like growth factor I. Endocrinology 123 (1988) 2827-2833
14. Asante E.A., Boswell J.M., Burt D.W., and Bulfield G. Tissue specific expression of an alpha-skeletal actin-lacZ fusion gene during development in transgenic mice. Transgenic Res. 3 (1994) 59-66
15. Shani M. Tissue-specific and developmentally regulated expression of a chimeric actin-globin gene in transgenic mice. Mol. Cell. Biol. 6 (1986) 2624-2631
16. Subramani S., Mulligan R., and Berg P. Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors. Mol. Cell. Biol. 1 (1981) 854-864
17. Owens P.C., Johnson R.J., Campbell R.G., and Ballard F.J. Growth hormone increases insulin-like growth factor-I (IGF-I) and decreases IGF-II in plasma of growing pigs. J. Endocrinol. 124 (1990) 269-275
18. Owens J.A., Kind K.L., Carbone F., Robinson J.S., and Owens P.C. Circulating insulin-like growth factors-I and -II and substrates in fetal sheep following restriction of placental growth. J. Endocrinol. 140 (1994) 5-13
19. Bell G.I., Stempien M.M., Fong N.M., and Rall L.B. Sequences of liver cDNAs encoding two different mouse insulin-like growth factor I precursors. Nucl. Acid Res. 14 (1986) 7873-7882
20. Upton Z., Webb H., Tomas F.M., Ballard F.J., and Francis G.L. Characterization of serum-derived and recombinant rat IGF-I and their use for measuring true concentrations of IGF-I in rat plasma. J. Endocrinol. 149 (1996) 379-387
21. Murray C., Warnes D., Ballard F.J., and Tomas F. Creatinine excretion as an index of myofibrillar protein mass in dystrophic mice. Clin. Sci. 61 (1981) 737-741
22. Anapol F., and Herring S.W. Ontogeny of histochemical fibre types and muscle function in the masseter muscle of miniature swine. Am. J. Phys. Anthropol. 112 (2000) 595-613
23. Anderson J.R. Atlas of Skeletal Muscle Pathology (1985), MTP Press Limited, Lancaster/Boston/The Hague/Dordrecht
24. Parry D.J., and Wilkinson R.S. The effect of reinnervation on the distribution of muscle fibre types in the tibialis anterior muscle of the mouse. Can. J. Physiol. Pharmacol. 68 (1990) 596-602
25. Shavlakadze T., White J.D., Davies M., Hoh J.F., and Grounds M.D. Insulin-like growth factor I slows the rate of denervation induced skeletal muscle atrophy. Neuromuscul. Disord. 15 (2005) 139-146
26. Bancroft J., and Stevens A. Theory and practice of histological techniques. Enzyme histochemistry (1996), Churchill Livingstone, New York pp. 391-410
27. Roberts P., and McGeachie J.K. Endothelial cell activation during angiogenesis in freely transplanted skeletal muscles in mice and its relationship to the onset of myogenesis. J. Anat. 169 (1990) 197-207
28. Shavlakadze T., Davies M., White J.D., and Grounds M.D. Early regeneration of whole skeletal muscle grafts is unaffected by overexpression of IGF-1 in MLC/mIGF-1 transgenic mice. J. Histochem. Cytochem. 52 (2004) 873-883
29. Bulfield G., Siller W.G., Wright P.A.L., and Moore K.J. X chromosome-linked muscular dystrophy (mdx) in the mouse. Proc. Natl Acad. Sci. 81 (1984) 1189-1192
30. Shavlakadze T., White J., Hoh J.F., Rosenthal N., and Grounds M.D. Targeted expression of insulin-like growth factor-I reduces early myofiber necrosis in dystrophic mdx mice. Mol. Ther. 10 (2004) 829-843
31. Straub V., Rafael J.A., Chamberlain J.S., and Campbell K.P. Animal models for muscular dystrophy show different patterns of sarcolemmal disruption. J. Cell Biol. 139 (1997) 375-385
32. Hamer P.W., McGeachie J.M., Davies M.J., and Grounds M.D. Evans blue dye used as an in vivo marker of myofibre fragility and damage in mice: defining optimal parameters. J. Anat. 200 (2002) 69-79
33. Coulton G.R., Morgan J.E., Partridge T.A., and Sloper J.C. The mdx mouse skeletal muscle myopathy: I. A histological, morphometric and biochemical investigation. Neuropathol. Appl. Neurobiol. 14 (1988) 53-70
34. Grounds M.D., and Torrisi J. Anti-TNFalpha (Remicade) therapy protects dystrophic skeletal muscle from necrosis. Faseb J. 18 (2004) 676-682
35. Barton E.R., Morris L., Musaro A., Rosenthal N., and Sweeney H.L. Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice. J. Cell Biol. 157 (2002) 137-148
36. Naranjo W.M., Yakar S., Sanchez-Gomez M., Perez A.U., Setser J., and LeRoith D. Protein calorie restriction affects nonhepatic IGF-I production and the lymphoid system: studies using the liver-specific IGF-I gene-deleted mouse model. Endocrinology 143 (2002) 2233-2241
37. Brahm H., Piehl-Aulin K., Saltin B., and Ljunghall S. Net fluxes over working thigh of hormones, growth factors and biomarkers of bone metabolism during short lasting dynamic exercise. Calcif. Tissue Int. 60 (1997) 175-180
38. Hizuka N., Takano K., Shizume K., et al. Insulin-like growth factor I stimulates growth in normal growing rats. Eur. J. Pharmacol. 125 (1986) 143-146
39. Tomas F.M., Knowles S.E., Chandler C.S., Francis G.L., Owens P.C., and Ballard F.J. Anabolic effects of insulin-like growth factor-I (IGF-I) and an IGF-I variant in normal female rats. J. Endocrinol. 137 (1993) 413-421
40. Criswell D.S., Booth F.W., DeMayo F., Schwartz R.J., Gordon S.E., and Fiorotto M.L. Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy. Am. J. Physiol. 275 (1998) E373-E379
41. Pursel V.G., Mitchell A.D., Bee G., et al. Growth and tissue accretion rates of swine expressing an insulin-like growth factor I transgene. Anim. Biotechnol. 15 (2004) 33-45
42. Lupu F., Terwilliger J.D., Lee K., Segre G.V., and Efstratiadis A. Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. Dev. Biol. 229 (2001) 141-162
43. Rosenfeld R.G., and Hintz R.L. Characterization of a specific receptor for somatomedin C (SM-C) on cultured human lymphocytes: evidence that sm-c modulates homologous receptor concentration. Endocrinology 107 (1980) 1841-1848
44. Watanabe N., Rosenfeld R.G., Hintz R.L., Dollar L.A., and Smith R.L. Characterization of a specific insulin-like growth factor-I/somatomedin-C receptor on high density, primary monolayer cultures of bovine articular chondrocytes: regulation of receptor concentration by somatomedin, insulin and growth hormone. J. Endocrinol. 107 (1985) 275-283
45. Toyofuku T., Hoffman J.R., Zak R., and Carlson B.M. Expression of alpha-cardiac and alpha-skeletal actin mRNAs in relation to innervation in regenerating and non-regenerating rat skeletal muscles. Dev. Dyn. 193 (1992) 332-339
46. Roberts P., and McGeachie J.K. The influence of revascularisation, vasoactive drugs and exercise on the regeneration of skeletal muscle, with particular reference to muscle transplantation. BAM 2 (1992) 5-16
47. Stitt T.N., Drujan D., Clarke B.A., et al. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol. Cell 14 (2004) 395-403
48. Day C.S., Buranapanitkit B., Riano F.A., et al. Insulin growth factor-1 decreases muscle atrophy following denervation. Microsurgery 22 (2002) 144-151
49. Bodine S.C., Stitt T.N., Gonzalez M., et al. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat. Cell Biol. 3 (2001) 1014-1019
50. Latres E., Amini A.R., Amini A.A., et al. IGF-1 inversely regulates atrophy-induced genes via the PI3K/Akt/mTOR pathway. J. Biol. Chem. 280 (2004) 2737-2744
51. Shani M. Tissue-specific and developmentally regulated expression of a chimeric actin-globin gene in transgenic mice. Mol. Cell Biol. 6 (1986) 2624-2633