C-type natriuretic peptide for reduction of restenosis: Gene transfer is superior over single peptide administration

Journal of Gene Medicine

Volumn 8, Issue 7, 2006, Pages 835-844

  Pelisek, Jaroslav ^a,b   Fuchs, Alexandra T ^b   Kuehnl, Andreas ^a   Tian, Wen ^a   Kuhlmann, Michael T ^a   Rolland, Pierre H ^c   Mekkaoui, Choukri ^c   Gaedtke, Lars ^b   Nikol, Sigrid ^a,d  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c AIX MARSEILLE UNIVERSITY   (France)

^d UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

C type natriuretic peptide; Endothelial repair; Gene transfer; Neointima formation; Restenosis

Indexed keywords

EVANS BLUE; LIPOSOME; NATRIURETIC PEPTIDE TYPE C;

ANGIOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMORAL ARTERY; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTIMA; MORPHOMETRICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTENOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; SWINE; VASCULAR SMOOTH MUSCLE;

ANGIOPLASTY, BALLOON; ANIMALS; BASE SEQUENCE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CONSTRICTION, PATHOLOGIC; DNA; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMORAL ARTERY; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; LIPOSOMES; MUSCLE, SMOOTH, VASCULAR; NATRIURETIC PEPTIDE, C-TYPE; SUS SCROFA;

SUIDAE; SUS SCROFA;

EID: 33746238259     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.905     Document Type: Article

References (41)

1. Liistro F, Colombo A. Late acute thrombosis after paclitaxel eluting stent implantation. Heart 2001; 86: 262-264.
2. Lowe HC, Oesterle SN, Khachigian LM. Coronary in-stent restenosis: current status and future strategies. J Am Coll Cardiol 2002; 39: 183-193.
3. Schofer J, Schluter M, Gershlick AH, et al. Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: double-blind, randomised controlled trial (E-SIRIUS). Lancet 2003; 362: 1093-1099.
4. Virmani R, Guagliumi G, Farb A, et al. Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious? Circulation 2004; 109: 701-705.
5. Virmani R, Liistro F, Stankovic G, et al. Mechanism of late in-stent restenosis after implantation of a paclitaxel derivate-eluting polymer stent system in humans. Circulation 2002; 106: 2649-2651.
6. Lemos PA, Saia F, Ligthart JM, et al. Coronary restenosis after sirolimus-eluting stent implantation: morphological description and mechanistic analysis from a consecutive series of cases. Circulation 2003; 108: 257-260.
7. Drachman DE. Clinical experience with drug-eluting stents. Rev Cardiovasc Med 2002; 3(Suppl 5): S31-S37.
8. Doi K, Ikeda T, Itoh H, et al. C-type natriuretic peptide induces redifferentiation of vascular smooth muscle cells with accelerated reendothelialization. Arterioscler Thromb Vasc Biol 2001; 21: 930-936.
9. Ohno N, Itoh H, Ikeda T, et al. Accelerated reendothelialization with suppressed thrombogenic property and neointimal hyperplasia of rabbit jugular vein grafts by adenovirus-mediated gene transfer of C-type natriuretic peptide. Circulation 2002; 105: 1623-1626.
10. Pelisek J, Kuehnl A, Rolland PH, et al. Functional analysis of genomic DNA, cDNA, and nucleotide sequence of the mature C-type natriuretic peptide gene in vascular cells. Arterioscler Thromb Vasc Biol 2004; 24: 1646-1651.
11. Hu Y, Zhang Z, Torsney E, et al. Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice. J Clin Invest 2004; 113: 1258-1265.
12. Li G, Chen SJ, Oparil S, et al. Direct in vivo evidence demonstrating neointimal migration of adventitial fibroblasts after balloon injury of rat carotid arteries. Circulation 2000; 101: 1362-1365.
13. Scott NA, Cipolla GD, Ross CE, et al. Identification of a potential role for the adventitia in vascular lesion formation after balloon overstretch injury of porcine coronary arteries. Circulation 1996; 93: 2178-2187.
14. Shi Y, O'Brien JE, Fard A, et al. Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries. Circulation 1996; 94: 1655-1664.
15. Nikol S, Huehns TY, Krausz E, et al. Needle injection catheter delivery of the gene for an antibacterial agent inhibits neointimal formation. Gene Ther 1999; 6: 737-748.
16. Pelisek J, Engelmann MG, Golda A, et al. Optimization of nonviral transfection: variables influencing liposome-mediated gene transfer in proliferating vs. quiescent cells in culture and in vivo using a porcine restenosis model. J Mol Med 2002; 80: 724-736.
17. Gonschior P, Pahl C, Huehns TY, et al. Comparison of local intravascular drug-delivery catheter systems. Am Heart J 1995; 130: 1174-1181.
18. Huehns TY, Krausz E, Mrochen S, et al. Neointimal growth can be influenced by local adventitial gene manipulation via a needle injection catheter. Atherosclerosis 1999; 144: 135-150.
19. Pelisek J, Armeanu S, Nikol S. Quiescence, cell viability, apoptosis and necrosis of smooth muscle cells using different growth inhibitors. Cell Prolif 2001; 34: 305-320.
20. Asahara T, Chen D, Tsurumi Y, et al. Accelerated restitution of endothelial integrity and endothelium-dependent function after phVEGF165 gene transfer. Circulation 1996; 94: 3291-3302.
21. Nikol S, Pelisek J, Engelmann MG, et al. Vascular endothelial growth factor (VEGF165) and its influence on angiogenesis versus arteriogenesis in different vascular beds. J Endovasc Ther 2002; 9: 842-854.
22. Barr CS, Rhodes P, Struthers AD. C-type natriuretic peptide. Peptides 1996; 17: 1243-1251.
23. Chrisman TD, Garbers DL. Reciprocal antagonism coordinates C-type natriuretic peptide and mitogen-signaling pathways in fibroblasts. J Biol Chem 1999; 274: 4293-4299.
24. Charles CJ, Espiner EA, Nicholls MG, et al. Clearance receptors and endopeptidase 24.11: equal role in natriuretic peptide metabolism in conscious sheep. Am J Physiol 1996; 271: R373-R380.
25. Colombo A, Drzewiecki J, Banning A, et al. Randomized study to assess the effectiveness of slow- and moderate-release polymer-based paclitaxel-eluting stents for coronary artery lesions. Circulation 2003; 108: 788-794.
26. Moses JW, Leon MB, Popma JJ, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med 2003; 349: 1315-1323.
27. Armeanu S, Pelisek J, Krausz E, et al. Optimization of nonviral gene transfer of vascular smooth muscle cells in vitro and in vivo. Mol Ther 2000; 1: 366-375.
28. Morishige K, Shimokawa H, Yamawaki T, et al. Local adenovirus-mediated transfer of C-type natriuretic peptide suppresses vascular remodeling in porcine coronary arteries in vivo. J Am Coll Cardiol 2000; 35: 1040-1047.
29. Ueno H, Haruno A, Morisaki N, et al. Local expression of C-type natriuretic peptide markedly suppresses neointimal formation in rat injured arteries through an autocrine/paracrine loop. Circulation 1997; 96: 2272-2279.
30. Templeton NS. Cationic liposome-mediated gene delivery in vivo. Biosci Rep 2002; 22: 283-295.
31. Huehns TY, Gonschior P, Hofling B. Adventitia as a target for intravascular local drug delivery. Heart 1996; 75: 537-538.
32. Post MJ, Borst C, Kuntz RE. The relative importance of arterial remodeling compared with intimal hyperplasia in lumen renarrowing after balloon angioplasty. Circulation 1994; 89: 2816-2821.
33. Barber MN, Gaspari TA, Kairuz EM, et al. Atrial natriuretic peptide preserves endothelial function during intimal hyperplasia. J Vasc Res 2005; 42: 101-110.
34. Kairuz EM, Barber MN, Anderson CR, et al. C-type natriuretic peptide (CNP) suppresses plasminogen activator inhibitor-1 (PAI-1) in vivo. Cardiovasc Res 2005; 66: 574-582.
35. Noel M, Caplice T, Jared B, et al. Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation. Proc Natl Acad Sci 2003; 100: 4754-4759.
36. Sata M. Circulating vascular progenitor cells contribute to vascular repair, remodeling, and lesion formation. Trends Cardiovasc Med 2003; 13: 249-253.
37. Fukuda D, Sata M, Tanaka K, et al. Potent inhibitory effect of sirolimus on circulating vascular progenitor cells. Circulation 2005; 111: 926-931.
38. Kaushal S, Amiel GE, Guleserian KJ, et al. Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nat Med 2001; 7: 1035-1040.
39. Zalewski A, Shi Y, Johnson AG. Diverse origin of intimal cells: smooth muscle cells, myofibroblasts, fibroblasts, and beyond? Circ Res 2002; 91: 652-655.
40. Baumgartner RBI, Do DD, Alerci M, et al. Late acute thrombotic occlusion after endovascular brachytherapy and stenting of femoropopliteal arteries. J Am Coll Cardiol 2003; 41: 409-412.
41. Mongiardo A, Curcio A, Spaccarotella C, et al. Molecular mechanisms of restenosis after percutaneous peripheral angioplasty and approach to endovascular therapy. Curr Drug Targets Cardiovasc Haematol Disord 2004; 4: 275-287.