Design, synthesis and evaluation of naphthalene-2-carboxamides as reversal agents in MDR cancer

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 17, 2006, Pages 6022-6026

  Lokhande, Tushar N ^a   Viswanathan, C L ^a   Joshi, Advait ^a   Juvekar, Aarti ^b  

^a BOMBAY COLLEGE OF PHARMACY   (India)

^b TATA MEMORIAL HOSPITAL   (India)

Author keywords

6 Methoxy naphthalene 2 carboxamides; Chemosensitizers; MDR reversal agents; P glycoprotein

Indexed keywords

DOXORUBICIN; N [3 (1 PIPERAZINYL)PROPYL] 6 METHOXYNAPHTHALENE 2 CARBOXAMIDE; N [3 (4 BUTYL 1 PIPERAZINYL)PROPYL] 6 METHOXYNAPHTHALENE 2 CARBOXAMIDE; N [3 (4 METHYL 1 PIPERAZINYL)PROPYL] 6 METHOXYNAPHTHALENE 2 CARBOXAMIDE; N [3 (4 METHYL 1 PIPERAZINYL)PROPYL]NAPHTHALENE 2 CARBOXAMIDE; N [3 (4 PHENYL 1 PIPERAZINYL)PROPYL] 6 METHOXYNAPHTHALENE 2 CARBOXAMIDE; N [3 (TERT BUTYL 1 PIPERAZINYL)PROPYL] 6 METHOXYNAPHTHALENE 2 CARBOXAMIDE; NAPHTHALENE DERIVATIVE; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RESISTANCE; CELL ASSAY; COMPUTER PROGRAM; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG DETERMINATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; LEUKEMIA CELL LINE; LYMPHATIC LEUKEMIA; LYMPHOCYTE CULTURE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PHARMACOPHORE; STRUCTURE ANALYSIS;

AMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG DESIGN; DRUG RESISTANCE, NEOPLASM; LEUKEMIA P388; MICE; MOLECULAR STRUCTURE; NAPHTHALENES;

MURINAE;

EID: 33746224173     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.05.010     Document Type: Article

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