Autoimmune targeted disruption of the pituitary-ovarian axis causes premature ovarian failure

Journal of Immunology

Volumn 177, Issue 3, 2006, Pages 1988-1996

  Altuntas, Cengiz Z ^a,b   Johnson, Justin M ^a   Tuohy, Vincent K ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CLEVELAND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; FOLLITROPIN; INHIBIN; INHIBIN ALPHA; INHIBIN ALPHA[215-234]; UNCLASSIFIED DRUG; VACCINE;

AMENORRHEA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; DIESTRUS; FEMALE; FEMALE INFERTILITY; GENE DISRUPTION; HYPOPHYSIS GONAD SYSTEM; HYPOPHYSIS OVARIAN AXIS; IMMUNIZATION; MALE; MOUSE; NONHUMAN; OVARY FOLLICLE MATURATION; OVARY INFLAMMATION; PREMATURE OVARIAN FAILURE; PRIORITY JOURNAL; SUPEROVULATION; T LYMPHOCYTE ACTIVATION;

EID: 33746215115     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.3.1988     Document Type: Article

References (50)

1. Coulam, C. B., S. C., Adamson, and J. F. Annegers. 1986. Incidence of premature ovarian failure. Obstet. Gynecol. 67: 604-606.
2. Anasti, J. N. 1998. Premature ovarian failure: an update. Fertil. Steril. 70: 1-15.
3. Marzotti, S., and Falorni, A. 2004. Addison's disease. Autoimmunity 37: 333-336.
4. Hoek, A., Y. van Kasteren, M. de Haan-Meulman, H. Hooijkaas, J. Schoemaker, and H. A. Drexhage. 1995. Analysis of peripheral blood lymphocyte subsets, NK cells, and delayed type hypersensitivity skin test in patients with premature ovarian failure. Am. J. Reprod. Immunol. 33: 495-502.
5. Chernyshov, V. P., T. V. Radysh, I. V. Gura, T. P. Tatarchuk, and Z. B. Khominskaya. 2001. Immune disorders in women with premature ovarian failure in initial period. Am. J. Reprod. Immunol. 46: 220-225.
6. Luborsky, J., B. Lianes, S. Davies, Z. Binor, E. Radwanska, and R. Pong. 1999. Ovarian autoimmunity: greater frequency of autoantibodies in premature menopause and unexplained infertility than in the general population. Clin. Immunol. 90: 368-374.
7. Forges, T., P. Monnier-Barbarino, G. C. Faure, and M. C. Bene. 2004. Autoimmunity and antigenic targets in ovarian pathology. Hum. Reprod. Update 10: 163-175.
8. Jankovic, B. D., B. M. Markovic, S. Petrovic, and K. Isakovic. 1973. Experimental autoimmuno-oophoritis in the rat. Eur. J. Immunol. 3: 375-377.
9. Ivanova, M., V. Bourneva, L. Gitsov, and Z. Angelova. 1984. Experimental immune oophoritis as a model for studying the thymus-ovary interaction. I. Morphological studies. Am. J. Reprod. Immunol. 6: 99-106.
10. Damjanovic, M. 1991. Experimental autoimmune oophoritis. II. Both lymphoid cells and antibodies are successful in adoptive transfer. Autoimmunity 9: 217-223.
11. Wood, D. M., C. Liu, and B. S. Dunbar. 1981. The effect of alloimmunization and heteroimmunization with zonae pellucidae on fertility in rabbits. Biol. Reprod. 25: 439-450.
12. Lou, Y., and K. S. Tung. 1993. T cell peptide of a self-protein elicits autoantibody to the protein antigen: implications for specificity and pathogenetic role of antibody in autoimmunity. J. Immunol. 151: 5790-5799.
13. Dean, J. 1992. Biology of mammalian fertilization: role of the zona pellucida. J. Clin. Invest. 89: 1055-1059.
14. Hoek, A., J. Schoemaker, and H. A. Drexhage. 1997. Premature ovarian failure and ovarian autoimmunity. Endocr. Rev. 18: 107-134.
15. Taguchi, O., Y. Nishizuka, T. Sakakura, and A. Kojima. 1980. Autoimmune oophoritis in thymectomized mice: detection of circulating antibodies against oocytes. Clin. Exp. Immunol. 40: 540-553.
16. Tung, K. S., S. Smith, C. Teuscher, C. Cook, and R. E. Anderson. 1987. Murine autoimmune oophoritis, epididymoorchitis, and gastritis induced by day 3 thymectomy: immunopathology. Am. J. Pathol. 126: 293-302.
17. Smith, H., Y. H. Lou, P. Lacy, and K. S. Tung. 1992. Tolerance mechanism in experimental ovarian and gastric autoimmune diseases. J. Immunol. 149: 2212-2218.
18. Shelling, A. N., K. A. Burton, A. L. Chand, C. C. van Ee, J. T. France, C. M. Farquhar, S. R. Milsom, D. R. Love, K. Gersak, K. Aittomaki, and I. M. Winship. 2000. Inhibin: a candidate gene for premature ovarian failure. Hum. Reprod. 15: 2644-2649.
19. Harris, S. E., A. L. Chand, I. M. Winship, K. Gersak, Y. Nishi, T. Yanase, H. Nawata, and A. N. Shelling. 2005. INHA promoter polymorphisms are associated with premature ovarian failure. Mol. Hum. Reprod. 11: 779-784.
20. Mayo, K. E. 1994. Inhibin and activin: molecular aspects of regulation and function. Trends Endocrin. Met. 5: 407-415.
21. Groome, N. P., P. J. Illingworth, M. O'Brien, I. Cooke, T. S. Ganesan, D. T. Baird, and A. S. McNeilly. 1994. Detection of dimeric inhibin throughout the human menstrual cycle by two-site enzyme immunoassay. Clin. Endocrinol. 40: 717-723.
22. Halvorson, L. M., and A. H. DeCherney. 1996. Inhibin, activin, and follistatin in reproductive medicine. Fertil. Steril. 65: 459-469.
23. Kumar, T. R., Y. Wang, N. Lu, and M. M. Matzuk. 1997. Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility. Nat. Genet. 15: 201-204.
24. Xu, J., K. McKeehan, K. Matsuzaki, and W. L. McKeehan. 1995. Inhibin antagonizes inhibition of liver cell growth by activin by a dominant-negative mechanism. J. Biol. Chem. 270: 6308-6313.
25. Dyson, S., and J. B. Gurdon. 1998. The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell. 93: 557-568.
26. Gray, P. C., J. Greenwald, A. L. Blount, K. S. Kunitake, C. J. Donaldson, S. Choe, and W. Vale. 2000. Identification of a binding site on the type II activin receptor for activin and inhibin. J. Biol. Chem. 275: 3206-3212.
27. Tone, S., Y. Katoh, H. Fujimoto, S. Togashi, M. Yanazawa, Y. Kato, and T. Higashinakagawa. 1990. Expression of inhibin α-subunit gene during mouse gametogenesis. Differentiation 44: 62-68.
28. Albano, R. M., N. Groome, and J. C. Smith. 1993. Activins are expressed in preimplantation mouse embryos and in ES and EC cells and are regulated on their differentiation. Development 117: 711-723.
29. + T cells specific for inner ear peptides. J. Clin. Invest. 113: 1210-1217.
30. Kananen, K., M. Markkula, M. Mikola, E. M. Rainio, A. McNeilly, and I. Huhtaniemi. 1996. Gonadectomy permits adrenocortical tumorigenesis in mice transgenic for the mouse inhibin α-subunit promoter/simian virus 40 T-antigen fusion gene: evidence for negative autoregulation of the inhibin α-subunit gene. Mol. Endocrinol. 10: 1667-1677.
31. Pierson, T. M., Y. Wang, F. J. DeMayo, M. M. Matzuk, S. Y. Tsai, and B. W. O'Malley. 2000. Regulable expression of inhibin A in wild-type and inhibin α null mice. Mol. Endocrinol. 14: 1075-1085.
32. Durlinger, A. L. L., M. J. G. Gruijters, B. Karels, T. R. Kumar, M. M. Matzuk, U. M. Rose, F. H. de Jong, J. T. Uilenbroek, J. A. Grootegoed, and A. P. N. Themmen. 2001. Anti-mullerian hormone attenuates the effects of FSH on follicle development in the mouse ovary. Endocrinology 142: 4891-4899.
33. Newton, H., Y. Wang, N. P. Groome, and P. Illingworth. 2002. Inhibin and activin secretion during murine preantral follicle culture and following HCG stimulation. Hum. Reprod. 17: 38-43.
34. National Hormone and Peptide Program (NHPP). 2004. New recombinant hormones, hypothalamic peptides, natural hormones, new antisera, and expanded hormone assay services available. J. Clin. Endocrinol. Metab. 89: 3618-3620.
35. Pedersen, T., and H. Peters. 1968. Proposal for a classification of oocytes and follicles in the mouse ovary. J. Reprod. Fertil. 17: 555-557.
36. Byskov, A. G. S. 1974. Cell kinetic studies of follicular atresia in the mouse ovary. J. Reprod. Fertil. 37: 277-285.
37. Rugh, R. 1990. Reproductive systems of adult mice. In The Mouse, Its Reproduction and Development, R. Rugh, ed. Oxford University Press, Oxford, pp. 24-43.
38. Miyazaki, S., K. Tanebe, M. Sakai, T. Michimata, H. Tsuda, M. Fujimura, M. Nakamura, Y. Kiso, and S. Saito. 2002. Interleukin 2 receptor γ chain (TC) knockout mice show less regularity in estrous cycle but achieve normal pregnancy without fetal compromise. Am. J. Reprod. Immunol. 47: 222-230.
39. Pernasetti, F., V. V. Vasilyev, S. B. Rosenberg, J. S. Bailey, H. J. Huang, W. L. Miller, and P. L. Mellon. 2001. Cell-specific transcriptional regulation of follicle-stimulating hormone-β by activin and gonadotropin-releasing hormone in the LβT2 pituitary gonadotroph cell model. Endocrinology 142: 2284-2295.
40. Turgeon, J. L., Y. Kimura, D. W. Waring, and P. L. Mellon. 1996. Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line. Mol. Endocrinol. 10: 439-450.
41. Graham, K. E., K. D. Nusser, and M. J. Low. 1999. LβT2 gonadotroph cells secrete follicle stimulating hormone (FSH) in response to active A. J. Endocrinol. 162: R1-5.
42. Anonymous. 1992. Recent advances in medically assisted conception: report of a WHO Scientific Group. World Health Organ. Tech. Rep. Ser. 820: 1-111.
43. Collins, J. A. 1995. Unexplained infertility. In Infertility: Evaluation and Treatment. W. R. Keye, Jr., R. J. Chang, R. W. Rebar, and M. R. Soules, eds. Saunders, Philadelphia, pp. 249-262.
44. Falorni, A., S. Laureti, P. Candeloro, S. Perrino, C. Coronella, A. Bizzarro, A. Bellastella, F. Santeusanio, and A. De Bellis. 2002. Steroid-cell autoantibodies are preferentially expressed in women with premature ovarian failure who have adrenal autoimmunity. Fertil. Steril. 78: 270-279.
45. Chiauzzi, V., S. Cigorraga, M. E. Escobar, M. A. Rivarola, and E. H. Charreau. 1982. Inhibition of follicle-stimulating hormone receptor binding by circulating immunoglobulins. J. Clin. Endocrinol. Metab. 54: 1221-1228.
46. Tang, V. W., and C. Faiman. 1983. Premature ovarian failure: a search for circulating factors against gonadotropin receptors. Am. J. Obstet. Gynecol. 146: 816-821.
47. Moncayo, H., R. Moncayo, R. Benz, A. Wolf, and C. Lauritzen. 1989. Ovarian failure and autoimmunity: detection of autoantibodies directed against both the unoccupied luteinizing hormone/human chorionic gonadotropin receptor and the hormone-receptor complex of bovine corpus luteum. J. Clin. Invest. 84: 1857-1865.
48. Luborsky, J. L., L. Visintin, S. Boyers, T. Asari, B. Caldwell, and A. DeCherney. 1990. Ovarian antibodies detected by immobilized antigen immunoassay in patients with premature ovarian failure. J. Clin. Endocr. Metab. 70: 69-75.
49. Kamada, M., T. Daitoh, K. Mori, N. Maeda, K. Hirano, M. Irahara, T. Aono, and T. Mori. 1992. Etiological implication of autoantibodies to zona pellucida in human female infertility. Am. J. Reprod. Immunol. 28: 104-109.
50. Avecillas, J. F., T. Falcone, and A. C. Arroliga. 2004. Ovarian hyperstimulation syndrome. Crit. Care Clin. 20: 679-695.