Laser-induced acoustic desorption mass spectrometry of single bioparticles

Angewandte Chemie - International Edition

Volumn 45, Issue 9, 2006, Pages 1423-1426

  Peng, Wen Ping ^a,b   Yang, Yi Chang ^a   Kang, Ming Wei ^a   Tzeng, Yan Kai ^c   Nie, Zongxiu ^a,d   Chang, Huan Cheng ^a,b,c   Chang, Wen ^e   Chen, Chung Hsuan ^b  

^a INSTITUTE OF ATOMIC AND MOLECULAR SCIENCES   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c NATIONAL TAIWAN NORMAL UNIVERSITY   (Taiwan)

^d WUHAN UNIVERSITY   (China)

^e INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

Author keywords

Analytical methods; Mass spectrometry; Single particle studies; Viruses

Indexed keywords

ANALYTICAL METHODS; BIOMEDICAL APPLICATIONS; SINGLE CHARGED BIOPARTICLES; SINGLE-PARTICLE STUDIES;

ACOUSTIC WAVES; BACTERIA; BIOMEDICAL ENGINEERING; CELLS; DESORPTION; LASERS; SENSITIVITY ANALYSIS; VIRUSES;

MASS SPECTROMETRY;

STEEL;

ARTICLE; CHEMISTRY; ERYTHROCYTE; ESCHERICHIA COLI; HUMAN; INSTRUMENTATION; LASER; MASS SPECTROMETRY; METHODOLOGY; PARTICLE SIZE; SENSITIVITY AND SPECIFICITY; SURFACE PROPERTY; VACCINIA VIRUS;

ERYTHROCYTES; ESCHERICHIA COLI; HUMANS; LASERS; MASS SPECTROMETRY; PARTICLE SIZE; SENSITIVITY AND SPECIFICITY; STEEL; SURFACE PROPERTIES; VACCINIA VIRUS;

EID: 33746215068     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200503271     Document Type: Article

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31. -2, a value which is much lower than that of small molecular ions desorbed/ionized by LIAD (Ref. [8]). Because of this low charge density, electron bombardment of negatively charged particles is possible.