TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis

Journal of Immunology

Volumn 177, Issue 3, 2006, Pages 1925-1931

  Brown, Heather J ^a   Lock, Helen R ^a   Sacks, Steven H ^a   Robson, Michael G ^a  

^a GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; CYSTEINE DERIVATIVE; MYELOID DIFFERENTIATION FACTOR 88; PALMITIC ACID DERIVATIVE; TOLL LIKE RECEPTOR 2;

ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; BONE MARROW CELL; CELL STIMULATION; CHIMERA; CONTROLLED STUDY; DISEASE EXACERBATION; GLOMERULONEPHRITIS; IMMUNE RESPONSE; INFECTION; INFLAMMATION; MESANGIUM CELL; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOSIS;

EID: 33746214773     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.3.1925     Document Type: Article

References (32)

1. Frimat, L., S. Briançon, D. Hestin, B. Aymard, E. Renoult, T. C. Huu, and M. Kessler. 1997. IgA nephropathy: prognostic classification of end-stage renal failure. Nephrol. Dial. Transplant. 12: 2569-2575.
2. Rees, A. J., C. M. Lockwood, and D. K. Peters. 1977. Enhanced allergic tissue injury in Goodpasture's syndrome by intercurrent bacterial infection. Br. Med. J. 2: 723-726.
3. Stegeman, C. A., J. W. Tervaert, W. J. Sluiter, W. L. Manson, P. E. de Jong, and C. G. Kallenberg. 1994. Association of chronic nasal carriage of Staphylococcus aureus and higher relapse rates in Wegener granulomatosis. Ann. Intern. Med. 120: 12-17.
4. Stegeman, C. A., J. W. Tervaert, P. E. de Jong, and C. G. Kallenberg. 1996. Trimethoprim-sulfamethoxazole (co-trimoxazole) for the prevention of relapses of Wegener's granulomatosis: Dutch Co-Trimoxazole Wegener Study Group. N. Engl. J. Med. 335: 16-20.
5. Takeda, K., T. Kaisho, and S. Akira. 2003. Toll-like receptors. Annu. Rev. Immunol. 9: 9.
6. Poltorak, A., X. He, I. Smirnova, M. Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282: 2085-2088.
7. Zarember, K. A., and P. J. Godowski. 2002. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J. Immunol. 168: 554-561.
8. Cochrane, C. G., E. R. Unanue, and F. J. Dixon. 1965. A role of polymorphonuclear leukocytes and complement in nephrotoxic nephritis. J. Exp. Med. 122: 99-119.
9. Hammer, D. K., and F. J. Dixon. 1963. Experimental glomerulonephritis. III. Immunologic events in the pathogenesis of nephrotoxic seum nephritis in the rat. J. Exp. Med. 117: 1019-1034.
10. Robson, M. G., H. T. Cook, C. D. Pusey, M. J. Walport, and K. A. Davies. 2003. Antibody-mediated glomerulonephritis in mice: the role of endotoxin, complement and genetic background. Clin. Exp. Immunol. 133: 326-333.
11. Karkar, A. M., and A. J. Rees. 1997. Influence of endotoxin contamination on anti-GBM antibody induced glomerular injury in rats. Kidney Int. 52: 1579-1583.
12. Hirschfeld, M., Y. Ma, J. H. Weis, S. N. Vogel, and J. J. Weis. 2000. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine Toll-like receptor 2. J. Immunol. 165: 618-622.
13. Robson, M. G., H. T. Cook, M. Botto, P. R. Taylor, N. Busso, R. Salvi, M. J. Walport, and K. A. Davies. 2001. Accelerated nephrotoxic nephritis is exacerbated in Clq-deficient mice. J. Immunol: 166: 620-628.
14. Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity. 11: 443-451.
15. Pfaffl, M. W. 2001. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29: e45.
16. Hayashi, F., T. K. Means, and A. D. Luster. 2003. Toll-like receptor's stimulate human neutrophil function. Blood 102: 2660-264.
17. Fan, J., and A. B. Malik. 2003. Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors. Nat. Med. 9: 315-321.
18. Sabroe, L. R. Prince, E. C. Jones, M. J. Horsburgh, S. J. Foster, S. N. Vogel, S. K. Dower, and M. K. Whyte. 2003. Selective roles for Toll-like receptor (TLR)2 and TLR4 in the regulation of neutrophil activation and life span. J. Immunol. 170: 5268-5275.
19. Andoheguii G., C. S. Bonder, F. Green, S. C. Mullaly, L. Zbytnuik, E. Raharjo, and P. Kubes. 2003. Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J. Clin. Invest. 111: 1011-1020.
20. Wolfs, T. G., W. A. Buurman, A. van Schadewijk, B. de Vries, M. A. Daemen, P. S. Hiemstra, and C. van't Veer. 2002. In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-γ and TNF-α mediated up-regulation during inflammation. J. Immunol. 168: 1286-1293.
21. Tsuboi, N., Y. Yoshikai, S. Matsuo, T. Kikuchi, K. Iwami, Y. Nagai, O. Takeuchi, S. Akira, and T. Matsuguchi. 2002. Roles of Toll-like receptors in C-C chemokine production by renal tubular epithelial cells. J. Immunol. 169: 2026-2033.
22. Brown, Z., R. M. Strieter, S. W. Chensue, M. Ceska, I. Lindley, G. H. Neild, S. L. Kunkel, and J. Westwick. 1991. Cytokine-activated human mesangial cells generate the neutrophil chemoattractant, interleukin 8. Kidney Int. 40: 86-90.
23. Bussolati, B., F. Mariano, L. Biancone, R. Foa, S. David, V. Cambi, and G. Camussi. 1999. Interleukin-12 is synthesized by mesangial cells and stimulates platelet-activating factor synthesis, cytoskeletal reorganization, and cell shape change. Am. J. Pathol. 154: 623-632.
24. Adler, S., P. J. Baker, R. J. Johnson, R. F. Ochi, P. Pritzl, and W. G. Couser. 1986. Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells. J. Clin. Invest. 77: 762-767.
25. Fouqueray, B., V. Boutard, C. Philippe, A. Kornreich, A. Marchant, J. Perez, M. Goldman, and L. Baud. 1995. Mesangial cell-derived interleukin-10 modulates mesangial cell response to lipopolysaccharide. Am. J. Pathol. 147: 176-182.
26. Feng, L., Y. Xia, J. I. Kreisberg, and C. B. Wilson. 1994. Interleukin-1α stimulates KC synthesis in rat mesangial cells: glucocorticoids inhibit KC induction by IL-1. Am. J. Physiol 266: F713-F722.
27. Grande, J. P., M. L. Jones, C. L. Swenson, P. D. Killen, and J. S. Warren. 1994. Lipopolysaccharide induces monocyte chemoattractant protein production by rat mesangial cells. J. Lab. Clin. Med. 124: 112-117.
28. Wolf, G., S. Aberle, F. Thaiss, P. J. Nelson, A. M. Krensky, E. G. Neilson, and R. A. Stahl. 1993. TNFα induces expression of the chemoattractant cytokine RANTES in cultured mouse mesangial cells. Kidney Int. 44: 795-804.
29. Patole, P. S., H. J. Grone, S. Segerer, R. Ciubar, E. Belemezova, A. Henger, M. Kretzler, D. Schlondorff, and H. J. Anders. 2005. Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells. J. Am. Soc. Nephrol. 16: 1326-1338.
30. Oquendo, P., J. Alberta, D. Z. Wen, J. L. Graycar, R. Derynck, and C. D. Stiles. 1989. The platelet-derived growth factor-inducible KC gene encodes a secretory protein related to platelet α-granule proteins. J. Biol. Chem. 264: 4133-4137.
31. Tekamp-Olson, P., C. Gallegos, D. Bauer, J. McClain, B. Sherry, M. Fabre, S. van Deventer, and A. Cerami. 1990. Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues. J. Exp. Med. 172: 911-919.
32. Schilling, J. D., S. M. Martin, C. S. Hung, R. G. Lorenz, and S. J. Hultgren. 2003. Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli. Proc. Natl. Acad. Sci. USA 100: 4203-4208.