Ligation of E-cadherin molecules on murine resident Langerhans cells inhibits their maturation and chemokine production

Journal of Dermatological Science

Volumn 43, Issue 2, 2006, Pages 152-155

  Fujita, Hideki ^a,b   Asahina, Akihiko ^a,b   Tamaki, Kunihiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SAGAMIHARA NATIONAL HOSPITAL   (Japan)

Author keywords

Chemokine; Dendritic cells; E cadherin; Langerhans cells; Skin

Indexed keywords

UVOMORULIN;

CELL MATURATION; DENDRITIC CELL; DOWN REGULATION; GENE MUTATION; HUMAN; LANGERHANS CELL; LETTER; LIGATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANIMALS; ANTIBODIES; CADHERINS; CHEMOKINES; DENDRITIC CELLS; LANGERHANS CELLS; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES;

EID: 33746207903     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2006.03.010     Document Type: Letter

References (10)

1. Liu Y.-J. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106 (2001) 259-262
2. Banchereau J., Briere F., Caux C., Davoust J., Lebecque S., Liu Y.-J., et al. Immunobiology of dendritic cells. Annu Rev Immunol 18 (2000) 767-811
3. Tang A., Amagai M., Granger L.G., Stanley J.R., and Udey M.C. Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin. Nature 361 (1993) 82-85
4. Riedl E., Stockl J., Majdic O., Scheinecker C., Knapp W., and Strobl H. Ligation of E-cadherin on in vitro-generated Langerhans-type dendritic cells inhibits their maturation. Blood 96 (2000) 4276-4284
5. Tada Y., Asahina A., Nakamura K., Tomura M., Fujiwara H., and Tamaki K. Granulocyte/macrophage colony-stimulating factor inhibits IL-12 production of mouse Langerhans cells. J Immunol 164 (2000) 5113-5119
6. Jakob T., and Udey M.C. Regulation of E-cadherin-mediated adhesion in Langerhans cell-like dendritic cells by inflammatory mediators that mobilize Langerhans cells in vivo. J Immunol 160 (1998) 4067-4073
7. Schwarzenberger K., and Udey M.C. Contact allergens and epidermal proinflammatory cytokines modulate Langerhans cell E-cadherin expression in situ. J Invest Dermatol 106 (1996) 553-558
8. Allam J.P., Geiger E., Kraft S., and Bieber T. Limited reliability of E-cadherin as a specific marker for in vitro-generated Langerhans cells. Arch Dermatol Res 295 (2003) 263-268
9. Fujita H., Asahina A., Gao P., Fujiwara H., and Tamaki K. Expression and regulation of RANTES/CCL5, MIP-1α/CCL3, and MIP-1β/CCL4 in mouse Langerhans cells. J Invest Dermatol 122 (2004) 1331-1333
10. Fujita H., Asahina A., Sugaya M., Nakamura K., Gao P., Fujiwara H., et al. Differential production of Th1- and Th2-type chemokines by mouse Lagerhans cells and splenic dendritic cells. J Invest Dermatol 124 (2005) 343-350