Arterial stiffness: A potential therapeutic target to reduce cardiovascular mortality

Current Hypertension Reviews

Volumn 2, Issue 2, 2006, Pages 97-102

  Saez, Anabelle Opazo ^a   Mitchell, Anna ^a   Philipp, Thomas ^a   Nürnberger, Jens ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Antihypertensive drugs; Calcium channel blockers; Cardiac contractility; Pulse wave velocity (PWV); Vasopeptidase inhibitors

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CAPTOPRIL; DIHYDRALAZINE; DILEVALOL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ENALAPRIL; FELODIPINE; GLYCERYL TRINITRATE; HYDROCHLOROTHIAZIDE; LACIDIPINE; NICARDIPINE; NIFEDIPINE; NITRATE; NITRENDIPINE; NITROPRUSSIDE SODIUM; OMAPATRILAT; PERINDOPRILAT; PLACEBO; QUINAPRIL; VASOPEPTIDASE INHIBITOR;

AGE; AORTA PRESSURE; ARTERY COMPLIANCE; BLOOD PRESSURE; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; DIABETES MELLITUS; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; ESSENTIAL HYPERTENSION; GENDER; HUMAN; HYPERCHOLESTEROLEMIA; ISCHEMIC HEART DISEASE; KIDNEY FAILURE; MORBIDITY; MORTALITY; NONHUMAN; NUTRITION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROGNOSIS; PULSE WAVE; REVIEW; SMOKING;

EID: 33746178086     PISSN: 15734021     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340206776877316     Document Type: Review

References (78)

1. Safar ME. Systolic blood pressure, pulse pressure and arterial stiffness as cardiovascular risk factors. Curr Opin Nephrol Hypertens 2001; 10:257-61.
2. Cameron JS, Hicks J. Frederick Akbar Mahomed and his role in the description of hypertension at Guy's Hospital. Kidney Int 1996; 49:1488-506.
3. O'Rourke M. Arterial Stiffness, Systolic Blood Pressure, and Logical Treatment of Arterial Hypertension. Hypertension 1990; 15:339-47.
4. Breithaupt-Grogler K, Belz GG. Epidemiology of the arterial stiffness. Pathol Biol (Paris) 1999; 47:604-13.
5. Belz GG. Elastic properties and windkessel function of the human aorta. Cardiovasc Drugs Ther 1995; 9:73-83.
6. Bank AJ, Kaiser DR. Smooth muscle relaxation: effects on arterial compliance, distensibility, elastic modulus, and pulse wave velocity. Hypertension 1998; 32:356-9.
7. Boutouyrie P, Laurent S, Benetos A, Girerd XJ, Hoeks AP, Safar ME. Opposing effects of ageing on distal and proximal large arteries in hypertensives. J Hypertens Suppl 1992; 10:S87-91.
8. Nichols WW, O'Rourke MF. McDonald's Blood Flow in Arteries. Theoretical, experimental and clinical principles. 4th ed ed. London: Edward Arnold 1998; p 54-401.
9. O'Rourke M. Mechanical principles in arterial disease. Hypertension 1995; 26:2-9.
10. O'Rourke MF, Staessen JA, Vlachopoulos C, Duprez D, Plante GE. Clinical applications of arterial stiffness; definitions and reference values. Am J Hypertens 2002; 15:426-44.
11. Shadwick RE. Mechanical design in arteries. J Exp Biol 1999; 202 Pt 23:3305-13.
12. Glasser SP, Arnett DK, McVeigh GE, Finkelstein SM, Bank AJ, Morgan DJ, et al. Vascular compliance and cardiovascular disease: a risk factor or a marker? Am J Hypertens 1997; 10:1175-89.
13. Karamanoglu M, O'Rourke MF, Avolio AP, Kelly RP. An analysis of the relationship between central aortic and peripheral upper limb pressure waves in man. Eur Heart J 1993; 14:160-7.
14. Barenbrock M, Spieker C, Laske V, Heidenreich S, Hohage H, Bachmann J, et al. Studies of the vessel wall properties in hemodialysis patients. Kidney Int 1994; 45:1397-400.
15. Munafo A, Christen Y, Nussberger J, Shum LY, Borland RM, Lee RJ, et al. Drug concentration response relationships in normal volunteers after oral administration of losartan, an angiotensin II receptor antagonist. Clin Pharmacol Ther 1992; 51:513-21.
16. Lacouciere Y, Brunner H, Irwin R, Karlberg BE, Ramsay LE, Snavely DB, et al. Effects of modulators of the renin-angiotensin-aldosterone system on cough. J Hypertens 1994; 12:1387-93.
17. Stefanadis C, Stratos C, Boudoulas H, Kourouklis C, Toutouzas P. Distensibility of the ascending aorta: comparison of invasive and non-invasive techniques in healthy men and in men with coronary artery disease. Eur Heart J 1990; 11:990-6.
18. Lehmann ED, Parker JR, Hopkins KD, Taylor MG, Gosling RG. Validation and reproducibility of pressure-corrected aortic distensibility measurements using pulse-wave-velocity Doppler ultrasound. J Biomed Eng 1993; 15:221-8.
19. Toto-Moukouo, Achimastos A, Asmar RG, Hughes CJ, Safar ME. Pulse wave velocity in patients with obesity and hypertension. Am Heart J 1986; 112:136-40.
20. Safar ME, London GM, Asmar RG, Hugues CJ, Laurent SA. An indirect approach for the study of the elastic modulus of the brachial artery in patients with essential hypertension. Cardiovasc Res 1986; 20:563-7.
21. O'Rourke MF, Mancia G. Arterial stiffness. J Hypertens 1999; 17:1-4.
22. Bramwell JC, Hill AV. Velocity of transmission of the pulse wave and elasticity of arteries. Lancet 1922; 1:891-2.
23. Frank O. Die Therorie der Pulswellen. Zeitschrift f. Biologie 1926; 85:9.
24. Breithaupt K, Erb KA, Neumann B, Wolf GK, Belz GG. Comparison of four noninvasive techniques to measure stroke volume: dual-beam doppler echoaortography, electrical impedance cardiography, mechanosphygmography and m mode echocardiography of the left ventricle. Am J Noninvas Cardiol 1990; 4:203-9.
25. Wilkinson IB, Fuchs SA, Jansen IM, Spratt JC, Murray GD, Cockcroft JR, et al. Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis. J Hypertens 1998; 16:2079-84.
26. Nurnberger J, Opazo Saez A, Dammer S, Michell A, Wenzel RR, Philipp T, et al. Left Ventricular Ejection Time: a Potential Determinant of Pulse Wave Velocity in Young, Healthy Males. J Hypertens 2003; 21:2125-32.
27. Avolio AP, Deng FQ, Li WQ, Luo YF, Huang ZD, Xing LF, et al. Effects of aging on arterial distensibility in populations with high and low prevalence of hypertension: comparison between urban and rural communities in China. Circulation 1985; 71:202-10.
28. Nurnberger J, Dammer S, Opazo Saez A, Philipp T, Schafers RF. Diastolic blood pressure is an important determinant of augmentation index and pulse wave velocity in young, healthy males. J Hum Hypertens 2003; 17:153-8.
29. Kelly R, Hayward C, Avolio A, O'Rourke M. Noninvasive determination of age-related changes in the human arterial pulse. Circulation 1989; 80:1652-9.
30. Franklin SS, Gustin Wt, Wong ND, Larson MG, Weber MA, Kannel WB, et al. Hemodynamic patterns of age-related changes in blood pressure. The Framingham Heart Study. Circulation 1997; 96:308-15.
31. Lantelme P, Mestre C, Lievre M, Gressard A, Milon H. Heart rate: an important confounder of pulse wave velocity assessment. Hypertension 2002; 39:1083-7.
32. O'Rourke MF, Pauca A, Jiang XJ. Pulse wave analysis. Br J Clin Pharmacol 2001; 51:507-22.
33. Megnien JL, Simon A, Valensi P, Pithois-Merli I, Assad N, Attali J, et al. [Comparison of isobaric effects of hypertension and diabetes mellitus on geometric and elastic properties of human arteries]. Arch Mal Coeur Vaiss 1991; 84:1101-3.
34. Armentano R, Simon A, Levenson J, Chan NP, Megnien JL, Pichel R. Mechanical pressure versus intrinsic effects of hypertension on large arteries in humans. Hypertension 1991; 18:657-64.
35. Hirai T, Sasayama S, Kawasaki T, Yagi S. Stiffness of systemic arteries in patients with myocardial infarction. A noninvasive method to predict severity of coronary atherosclerosis. Circulation 1989; 80:78-86.
36. Takazawa K, O'Rourke MF, Fujita M, Tanaka N, Takeda K, Kurosu F, et al. Estimation of ascending aortic pressure from radial arterial pressure using a generalised transfer function. Z Kardiol 1996; 85:137-9.
37. Chen CH, Nevo E, Fetics B, Pak PH, Yin FC, Maughan WL, et al. Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure. Validation of generalized transfer function. Circulation 1997; 95:1827-36.
38. Yasmin, Brown MJ. Similarities and differences between augmentation index and pulse wave velocity in the assessment of arterial stiffness. QJM 1999; 92:595-600.
39. O'Rourke MF, Avolio AP, Lauren AP, Young J. Age related changes of elastic lamellae in the human thoracic aorta. J Am Coll Cardiol 1987; 9:53A (abstract).
40. Ting CT, Yang TM, Chen JW, Chang MS, Yin FC. Arterial hemodynamics in human hypertension. Effects of angiotensin converting enzyme inhibition. Hypertension 1993; 22:839-46.
41. Levy BI, Curmi P, Poitevin P, Safar ME. Modifications of the arterial mechanical properties of normotensive and hypertensive rats without arterial pressure changes. J Cardiovasc Pharmacol 1989; 14:253-9.
42. Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L, et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 2001; 37:1236-41.
43. Blacher J, Guerin AP, Pannier B, Marchais SJ, Safar ME, London GM. Impact of aortic stiffness on survival in end-stage renal disease. Circulation 1999; 99:2434-9.
44. Cruickshank K, Riste L, Anderson SG, Wright JS, Dunn G, Gosling RG. Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function? Circulation 2002; 106:2085-90.
45. London GM, Blacher J, Pannier B, Guerin AP, Marchais SJ, Safar ME. Arterial wave reflections and survival in end-stage renal failure. Hypertension 2001; 38:434-8.
46. Wilkinson IB, Qasem A, McEniery CM, Webb DJ, Avolio AP, Cockcroft JR. Nitric oxide regulates local arterial distensibility in vivo. Circulation 2002; 105:213-7.
47. London GM, Guerin AP, Pannier B, Marchais SJ, Safar ME. Large artery structure and function in hypertension and end-stage renal disease. J Hypertens 1998; 16:1931-8.
48. Kass DA, Shapiro EP, Kawaguchi M, Capriotti AR, Scuteri A, deGroof RC, et al. Improved arterial compliance by a novel advanced glycation end-product crosslink breaker. Circulation 2001; 104:1464-70.
49. Kelly RP, Gibbs HH, O'Rourke MF, Daley JE, Mang K, Morgan JJ, et al. Nitroglycerin has more favourable effects on left ventricular afterload than apparent from measurement of pressure in a peripheral artery. Eur Heart J 1990; 11:138-44.
50. Van Bortel LM, Struijker-Boudier HA, Safar ME. Pulse pressure, arterial stiffness, and drug treatment of hypertension. Hypertension 2001; 38:914-21.
51. Ting CT, Chen CH, Chang MS, Yin FC. Short- and long-term effects of antihypertensive drugs on arterial reflections, compliance, and impedance. Hypertension 1995; 26:524-30.
52. Simkus GJ, Fitchett DH. Radial arterial pressure measurements may be a poor guide to the beneficial effects of nitroprusside on left ventricular systolic pressure in congestive heart failure. Am J Cardiol 1990; 66:323-6.
53. Kelly R, Daley J, Avolio A, O'Rourke M. Arterial dilation and reduced wave reflection. Benefit of dilevalol in hypertension. Hypertension 1989; 14:14-21.
54. Pauca AL, Kon ND, O'Rourke M F. Benefit of nitroglycerin on arterial stiffness is directly due to effects on peripheral arteries. Heart 2005.
55. Jiang XJ, O'Rourke MF, Jin WQ, Liu LS, Li CW, Tai PC, et al. Quantification of glyceryl trinitrate effect through analysis of the synthesised ascending aortic pressure waveform. Heart 2002; 88:143-8.
56. Bouthier JD, De Luca N, Safar ME, Simon AC. Cardiac hypertrophy and arterial distensibility in essential hypertension. Am Heart J 1985; 109:1345-52.
57. Asmar R, Benetos A, Brahimi M, Chaouche K, Safar M. Arterial and antihypertensive effects of nitrendipine: a double-blind comparison versus placebo. J Cardiovasc Pharmacol 1992; 20:858-63.
58. Asmar R, Benetos A, Ghodsi N, Meilhac B, Safar M. [Regional arterial hemodynamics and carotid circulation in essential arterial hypertension. Effect of nitrendipine in patients over 40 years of age]. Presse Med 1993; 22:1770-5.
59. Pannier BM, Lafleche AB, Girerd XJ, London GM, Safar ME. Arterial stiffness and wave reflections following acute calcium blockade in essential hypertension. Am J Hypertens 1994; 7:168-76.
60. Levy BI, Duriez M, Phillipe M, Poitevin P, Michel JB. Effect of chronic dihydropyridine (isradipine) on the large arterial walls of spontaneously hypertensive rats. Circulation 1994; 90:3024-33.
61. Benetos A, Cambien F, Gautier S, Ricard S, Safar M, Laurent S, et al. Influence of the angiotensin II type 1 receptor gene polymorphism on the effects of perindopril and nitrendipine on arterial stiffness in hypertensive individuals. Hypertension 1996; 28:1081-4.
62. De Cesaris R, Ranieri G, Filitti V, Andriani A. Large artery compliance in essential hypertension. Effects of calcium antagonism and beta-blocking. Am J Hypertens 1992; 5:624-8.
63. Tedeschi C, Guarini P, Giordano G. Messina V, Cicatiello AM, Iovino L, et al. Effects of nicardipine on intimal-medial thickness and arterial distensibility in hypertensive patients. Preliminary results after 6 months. Int Angiol 1993; 12:344-7.
64. Asmar RG, Benetos A, Chaouche-Teyara K, Raveau-Landon CM, Safar ME. Comparison of effects of felodipine versus hydrochlorothiazide on arterial diameter and pulse-wave velocity in essential hypertension. Am J Cardiol 1993; 72:794-8.
65. Pancera P, Arosio E, Arcaro G, Priante F, Montesi G, Paluani F, et al. Haemodynamic parameters in hypertensive patients: changes induced by lacidipine and nifedipine. J Hypertens Suppl 1989; 7:S284-5.
66. Simon A, Merli I, Del Pino M, Brautigam M, Welzel D, Burger KJ, et al. [Vasoselective, substance-specific actions of isradipine on the great arteries of hypertensives in comparison to metoprolol]. Arzneimittelforschung 1994; 44:305-9.
67. Topouchian J, Asmar R, Sayegh F, Rudnicki A, Benetos A, Bacri AM, et al. Changes in arterial structure and function under trandolapril-verapamil combination in hypertension. Stroke 1999; 30:1056-64.
68. London GM, Pannier B, Vicaut E, Guerin AP, Marchais SJ, Safar ME, et al. Antihypertensive effects and arterial haemodynamic alterations during angiotensin converting enzyme inhibition. J Hypertens 1996; 14:1139-46.
69. Topouchian J, Brisac AM, Pannier B, Vicaut E, Safar M, Asmar R. Assessment of the acute arterial effects of converting enzyme inhibition in essential hypertension: a double-blind, comparative and crossover study. J Hum Hypertens 1998; 12:181-7.
70. Benetos A, Santoni JP, Safar ME. Vascular effects of intravenous infusion of the angiotensin converting enzyme inhibitor perindoprilat. J Hypertens 1990; 8:819-26.
71. Mitchell GF, Izzo JL Jr, Lacourciere Y, Ouellet JP, Neutel J, Qian C, et al. Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension: results of the conduit hemodynamics of omapatrilat international research study. Circulation 2002; 105:2955-61.
72. Mahmud A, Feely J. Favourable effects on arterial wave reflection and pulse pressure amplification of adding angiotensin II receptor blockade in resistant hypertension. J Hum Hypertens 2000; 14:541-6.
73. Mahmud A, Feely J. Effect of angiotensin ii receptor blockade on arterial stiffness: beyond blood pressure reduction. Am J Hypertens 2002; 15:1092-5.
74. Mahmud A, Feely J. Reduction in arterial stiffness with angiotensin II antagonist is comparable with and additive to ACE inhibition. Am J Hypertens 2002; 15:321-5.
75. Mourlon-Le Grand MC, Poitevin P, Benessiano J, Duriez M, Michel JB, Levy BI. Effect of a nonhypotensive long-term infusion of ANP on the mechanical and structural properties of the arterial wall in Wistar-Kyoto and spontaneously hypertensive rats. Arterioscler Thromb 1993; 13:640-50.
76. Ting CT, Chou CY, Chang MS, Wang SP, Chiang BN, Yin FC. Arterial hemodynamics in human hypertension. Effects of adrenergic blockade. Circulation 1991; 84:1049-57.
77. Asmar RG, Kerihuel JC, Girerd XJ, Safar ME. Effect of bisoprolol on blood pressure and arterial hemodynamics in systemic hypertension. Am J Cardiol 1991; 68:61-4.
78. Benetos A, Lafleche A, Asmar R, Gautier S, Safar A, Safar ME. Arterial stiffness, hydrochlorothiazide and converting enzyme inhibition in essential hypertension. J Hum Hypertens 1996; 10:77-82.