메뉴 건너뛰기




Volumn 20, Issue 8, 2006, Pages 1393-1399

Molecular response in acute promyelocytic leukemia: A direct comparison of regular and real-time RT-PCR

Author keywords

Acute promyelocytic leukemia; Molecular response; PML RAR ; Real time RT PCR

Indexed keywords

ARSENIC TRIOXIDE; CYTARABINE; DAUNORUBICIN; FLT3 LIGAND; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HOMOHARRINGTONINE; METHOTREXATE; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA;

EID: 33746173336     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404262     Document Type: Article
Times cited : (12)

References (39)
  • 1
    • 0035145671 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: Clinical and morphologic features and prognostic factors
    • Avvisati G, Lo Coco F, Mandelli F. Acute promyelocytic leukemia: clinical and morphologic features and prognostic factors. Semin Hematol 2001; 38: 4-12.
    • (2001) Semin Hematol , vol.38 , pp. 4-12
    • Avvisati, G.1    Lo Coco, F.2    Mandelli, F.3
  • 2
    • 0023752982 scopus 로고
    • Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
    • Huang ME, Ye YC, Chen SR, Chai JR, Zhoa L, Wang ZY. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 1988; 72: 567-572.
    • (1988) Blood , vol.72 , pp. 567-572
    • Huang, M.E.1    Ye, Y.C.2    Chen, S.R.3    Chai, J.R.4    Zhoa, L.5    Wang, Z.Y.6
  • 3
    • 0035145435 scopus 로고    scopus 로고
    • All-trans retinoic acid and chemotherapy in the treatment of acute promyelocytic leukemia
    • Fenaux P, Chomienne C, Degos L. All-trans retinoic acid and chemotherapy in the treatment of acute promyelocytic leukemia. Semin Hematol 2001; 38: 13-25.
    • (2001) Semin Hematol , vol.38 , pp. 13-25
    • Fenaux, P.1    Chomienne, C.2    Degos, L.3
  • 5
    • 0032487923 scopus 로고    scopus 로고
    • Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
    • Soignet SL, Maslak P, Wang ZG, Jhanwar S, Calleja E, Dardashti LJ et al. Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N Engl J Med 1998; 339: 1341-1348.
    • (1998) N Engl J Med , vol.339 , pp. 1341-1348
    • Soignet, S.L.1    Maslak, P.2    Wang, Z.G.3    Jhanwar, S.4    Calleja, E.5    Dardashti, L.J.6
  • 6
    • 0010740572 scopus 로고    scopus 로고
    • 3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
    • 3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins. Blood 1996; 88: 1052-1061.
    • (1996) Blood , vol.88 , pp. 1052-1061
    • Chen, G.Q.1    Zhu, J.2    Shi, X.G.3    Ni, J.H.4    Zhong, H.J.5    Si, G.Y.6
  • 7
    • 0033526012 scopus 로고    scopus 로고
    • Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia
    • Lallemand-Breitenbach V, Guillemin MC, Janin A, Daniel MT, Degos L, Kogan SC et al. Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia. J Exp Med 1999; 189: 1043-1052.
    • (1999) J Exp Med , vol.189 , pp. 1043-1052
    • Lallemand-Breitenbach, V.1    Guillemin, M.C.2    Janin, A.3    Daniel, M.T.4    Degos, L.5    Kogan, S.C.6
  • 8
    • 0035161286 scopus 로고    scopus 로고
    • Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
    • Jing Y, Wang L, Xia L, Chen GQ, Chen Z, Miller WH et al. Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo. Blood 2001; 97: 264-269.
    • (2001) Blood , vol.97 , pp. 264-269
    • Jing, Y.1    Wang, L.2    Xia, L.3    Chen, G.Q.4    Chen, Z.5    Miller, W.H.6
  • 9
    • 11144355810 scopus 로고    scopus 로고
    • 3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia
    • 3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Proc Natl Acad Sci USA 2004; 101: 5328-5335.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 5328-5335
    • Shen, Z.X.1    Shi, Z.Z.2    Fang, J.3    Gu, B.W.4    Li, J.M.5    Zhu, Y.M.6
  • 10
    • 0026652137 scopus 로고
    • A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia
    • Castaigne S, Balitrand N, de The H, Dejean A, Degos L, Chomienne C. A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia. Blood 1992; 79: 3110-3115.
    • (1992) Blood , vol.79 , pp. 3110-3115
    • Castaigne, S.1    Balitrand, N.2    de The, H.3    Dejean, A.4    Degos, L.5    Chomienne, C.6
  • 13
    • 0028983312 scopus 로고
    • Molecular analysis of PML-RAR alpha fusion mRNA detected by reverse transcription-polymerase chain reaction assay in long-term disease-free acute promyelocytic leukaemia patients
    • Martinelli G, Remiddi C, Visani G, Farabegoli P, Testoni N, Zaccaria A et al. Molecular analysis of PML-RAR alpha fusion mRNA detected by reverse transcription-polymerase chain reaction assay in long-term disease-free acute promyelocytic leukaemia patients. Br J Haematol 1995; 90: 966-968.
    • (1995) Br J Haematol , vol.90 , pp. 966-968
    • Martinelli, G.1    Remiddi, C.2    Visani, G.3    Farabegoli, P.4    Testoni, N.5    Zaccaria, A.6
  • 14
    • 0032147033 scopus 로고    scopus 로고
    • Early detection of relapse by prospective reverse transcriptase-polymerase chain reaction analysis of the PML/RARalpha fusion gene in patients with acute promyelocytic leukemia enrolled in the GIMEMA-AIEOP multicenter 'AIDA' trial. GIMEMA-AIEOP Multi-center 'AIDA' Trial
    • Diverio D, Rossi V, Avvisati G, De Santis S, Pistilli A, Pane F et al. Early detection of relapse by prospective reverse transcriptase-polymerase chain reaction analysis of the PML/RARalpha fusion gene in patients with acute promyelocytic leukemia enrolled in the GIMEMA-AIEOP multicenter 'AIDA' trial. GIMEMA-AIEOP Multi-center 'AIDA' Trial. Blood 1998; 92: 784-789.
    • (1998) Blood , vol.92 , pp. 784-789
    • Diverio, D.1    Rossi, V.2    Avvisati, G.3    De Santis, S.4    Pistilli, A.5    Pane, F.6
  • 15
    • 0030825408 scopus 로고    scopus 로고
    • Molecular remission in PML/RAR alpha-positive acute promyelocytic leukemia by combined all-trans retinoic acid and idarubicin (AIDA) therapy
    • Gruppo Italiano-Malattie Ematologiche Maligne dell'Adulto and Associazione Italiana di Ematologia ed Oncooga Pediatrica Cooperative Groups
    • Mandelli F, Diverio D, Avvisati G, Luciano A, Barbui T, Bernasconi C et al. Molecular remission in PML/RAR alpha-positive acute promyelocytic leukemia by combined all-trans retinoic acid and idarubicin (AIDA) therapy. Gruppo Italiano-Malattie Ematologiche Maligne dell'Adulto and Associazione Italiana di Ematologia ed Oncooga Pediatrica Cooperative Groups. Blood 1997; 90: 1014-1021.
    • (1997) Blood , vol.90 , pp. 1014-1021
    • Mandelli, F.1    Diverio, D.2    Avvisati, G.3    Luciano, A.4    Barbui, T.5    Bernasconi, C.6
  • 17
    • 0036798706 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: A model for the role of molecular diagnosis and residual disease monitoring in directing treatment approach in acute myeloid leukemia
    • Grimwade D, Lo Coco F. Acute promyelocytic leukemia: A model for the role of molecular diagnosis and residual disease monitoring in directing treatment approach in acute myeloid leukemia. Leukemia 2002; 16: 1959-1973.
    • (2002) Leukemia , vol.16 , pp. 1959-1973
    • Grimwade, D.1    Lo Coco, F.2
  • 18
    • 0033975927 scopus 로고    scopus 로고
    • Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCR
    • Cassinat B, Zassadowski F, Balitrand N, Barbey C, Rain JD, Fenaux P et al. Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCR. Leukemia 2000; 14: 324-328.
    • (2000) Leukemia , vol.14 , pp. 324-328
    • Cassinat, B.1    Zassadowski, F.2    Balitrand, N.3    Barbey, C.4    Rain, J.D.5    Fenaux, P.6
  • 19
    • 0034769846 scopus 로고    scopus 로고
    • Feasibility and clinical significance of real-time quantitative RT-PCR assay of PML-RARalpha fusion transcript in patients with acute promyelocytic leukemia
    • Gu BW, Hu J, Xu L, Yan H, Jin WR, Zhu YM et al. Feasibility and clinical significance of real-time quantitative RT-PCR assay of PML-RARalpha fusion transcript in patients with acute promyelocytic leukemia. Hematol J 2001; 2: 330-340.
    • (2001) Hematol J , vol.2 , pp. 330-340
    • Gu, B.W.1    Hu, J.2    Xu, L.3    Yan, H.4    Jin, W.R.5    Zhu, Y.M.6
  • 20
    • 0038446666 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR analysis of PML-RAR alpha mRNA in acute promyelocytic leukemia: Assessment of prognostic significance in adult patients from intergroup protocol 0129
    • Gallagher RE, Yeap BY, Livak KJ, Beaubier N, Bloomfield CD, Appelbaum FR et al. Quantitative real-time RT-PCR analysis of PML-RAR alpha mRNA in acute promyelocytic leukemia: Assessment of prognostic significance in adult patients from intergroup protocol 0129. Blood 2003; 101: 2521-2528.
    • (2003) Blood , vol.101 , pp. 2521-2528
    • Gallagher, R.E.1    Yeap, B.Y.2    Livak, K.J.3    Beaubier, N.4    Bloomfield, C.D.5    Appelbaum, F.R.6
  • 21
    • 0027194394 scopus 로고
    • Acute promyelocytic leukemia: Clinical relevance of two major PML-RAR alpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse
    • Huang W, Sun GL, Li XS, Cao Q, Lu Y, Jang GS et al. Acute promyelocytic leukemia: Clinical relevance of two major PML-RAR alpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse. Blood 1993; 82: 1264-1269.
    • (1993) Blood , vol.82 , pp. 1264-1269
    • Huang, W.1    Sun, G.L.2    Li, X.S.3    Cao, Q.4    Lu, Y.5    Jang, G.S.6
  • 22
    • 0033134792 scopus 로고    scopus 로고
    • Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia
    • Leukemia Study Group of the Ministry of Health and Welfare (Koheseisho)
    • Kiyoi H, Naoe T, Yokota S, Nakao M, Minami S, Kuriyama K et al. Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia. Leukemia Study Group of the Ministry of Health and Welfare (Koheseisho). Blood 1999; 93: 3074-3080.
    • (1999) Blood , vol.93 , pp. 3074-3080
    • Kiyoi, H.1    Naoe, T.2    Yokota, S.3    Nakao, M.4    Minami, S.5    Kuriyama, K.6
  • 23
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958; 53: 457-481.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 24
    • 0017365573 scopus 로고
    • Design and analysis of randomized clinical trials requiring prolonged observations of each patient, II: Analysis and examples
    • Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV et al. Design and analysis of randomized clinical trials requiring prolonged observations of each patient, II: Analysis and examples. Br J Cancer 1977; 35: 1-39.
    • (1977) Br J Cancer , vol.35 , pp. 1-39
    • Peto, R.1    Pike, M.C.2    Armitage, P.3    Breslow, N.E.4    Cox, D.R.5    Howard, S.V.6
  • 25
    • 0033564337 scopus 로고    scopus 로고
    • Presenting white blood cell count and kinetics of molecular remission predict prognosis in acute promyelocytic leukemia treated with all-trans retinoic acid: Result of the randomized MRC trial
    • Burnett AK, Grimwade D, Solomon E, Wheatley K, Goldstone AH. Presenting white blood cell count and kinetics of molecular remission predict prognosis in acute promyelocytic leukemia treated with all-trans retinoic acid: Result of the randomized MRC trial. Blood 1999; 93: 4131-4143.
    • (1999) Blood , vol.93 , pp. 4131-4143
    • Burnett, A.K.1    Grimwade, D.2    Solomon, E.3    Wheatley, K.4    Goldstone, A.H.5
  • 26
    • 0035525767 scopus 로고    scopus 로고
    • Prognostic significance of minimal residual disease detection and PML/RAR-α isoform type: Long-term follow-up in acute promyelocytic leukemia
    • Jurcic JG, Nimer SD, Scheinberg DA, DeBlasio T, Warrell Jr RP, Miller Jr WH. Prognostic significance of minimal residual disease detection and PML/RAR-α isoform type: Long-term follow-up in acute promyelocytic leukemia. Blood 2001; 98: 2651-2656.
    • (2001) Blood , vol.98 , pp. 2651-2656
    • Jurcic, J.G.1    Nimer, S.D.2    Scheinberg, D.A.3    DeBlasio, T.4    Warrell Jr., R.P.5    Miller Jr., W.H.6
  • 27
    • 0030061520 scopus 로고    scopus 로고
    • Minimal residual disease detection in acute promyelocytic leukemia by reverse-transcriptase PCR: Evaluation of PML-RARα and RARα-PML assessment in patients who ultimately relapse
    • Grimwade D, Howe K, Langabeer S, Burnett A, Goldstone A, Solomon E. Minimal residual disease detection in acute promyelocytic leukemia by reverse-transcriptase PCR: Evaluation of PML-RARα and RARα-PML assessment in patients who ultimately relapse. Leukemia 1996; 10: 61-66.
    • (1996) Leukemia , vol.10 , pp. 61-66
    • Grimwade, D.1    Howe, K.2    Langabeer, S.3    Burnett, A.4    Goldstone, A.5    Solomon, E.6
  • 28
    • 0026446190 scopus 로고
    • Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia
    • Lo Coco F, Diverio D, Pandolfi PP, Biondi A, Rossi V, Avvisati G et al. Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia. Lancet 1992; 340: 1437-1438.
    • (1992) Lancet , vol.340 , pp. 1437-1438
    • Lo Coco, F.1    Diverio, D.2    Pandolfi, P.P.3    Biondi, A.4    Rossi, V.5    Avvisati, G.6
  • 29
    • 2142805764 scopus 로고    scopus 로고
    • Monitoring PML-RARalpha in acute promyelocytic leukemia
    • Jurcic JG. Monitoring PML-RARalpha in acute promyelocytic leukemia. Curr Oncol Rep 2003; 5: 391-398.
    • (2003) Curr Oncol Rep , vol.5 , pp. 391-398
    • Jurcic, J.G.1
  • 30
    • 9144222001 scopus 로고    scopus 로고
    • Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - A Europe Against Cancer program
    • Gabert J, Beillard E, van der Velden VH, Bi W, Grimwade D, Pallisgaard N et al. Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program. Leukemia 2003; 7: 2318-2357.
    • (2003) Leukemia , vol.7 , pp. 2318-2357
    • Gabert, J.1    Beillard, E.2    van der Velden, V.H.3    Bi, W.4    Grimwade, D.5    Pallisgaard, N.6
  • 31
    • 0026507163 scopus 로고
    • Occurrence of distinct PML-RAR-alpha fusion gene isoforms in patients with acute promyelocytic leukemia detected by reverse transcriptase/polymerase chain reaction
    • Chen SJ, Chen Z, Chen A, Tong JH, Dong S, Wang ZY et al. Occurrence of distinct PML-RAR-alpha fusion gene isoforms in patients with acute promyelocytic leukemia detected by reverse transcriptase/polymerase chain reaction. Oncogene 1992; 7: 1223-1232.
    • (1992) Oncogene , vol.7 , pp. 1223-1232
    • Chen, S.J.1    Chen, Z.2    Chen, A.3    Tong, J.H.4    Dong, S.5    Wang, Z.Y.6
  • 32
    • 2342541801 scopus 로고    scopus 로고
    • A surrogate marker profile for PML/RAR alpha expressing acute promyelocytic leukemia and the association of immunophenotypic markers with morphologic and molecular subtypes
    • Eastern Cooperative Oncology Group
    • Paietta E, Goloubeva O, Neuberg D, Bennett JM, Gallagher R, Racevskis J, et al., Eastern Cooperative Oncology Group. A surrogate marker profile for PML/RAR alpha expressing acute promyelocytic leukemia and the association of immunophenotypic markers with morphologic and molecular subtypes. Cytometry B Clin Cytom 2004; 59: 1-9.
    • (2004) Cytometry B Clin Cytom , vol.59 , pp. 1-9
    • Paietta, E.1    Goloubeva, O.2    Neuberg, D.3    Bennett, J.M.4    Gallagher, R.5    Racevskis, J.6
  • 33
    • 0027937940 scopus 로고
    • Early mortality and retinoic acid syndrome in acute promyelocytic leukemia: Impact of leukocytosis, low-dose chemotherapy, PML/RARα isoform, and CD13 expression in patients treated with all-trans retinoid acid
    • Vahdat L, Maslak P, Miller Jr WH, Eardley A, Heller G, Scheinberg DA et al. Early mortality and retinoic acid syndrome in acute promyelocytic leukemia: Impact of leukocytosis, low-dose chemotherapy, PML/RARα isoform, and CD13 expression in patients treated with all-trans retinoid acid. Blood 1994; 84: 3843-3849.
    • (1994) Blood , vol.84 , pp. 3843-3849
    • Vahdat, L.1    Maslak, P.2    Miller Jr., W.H.3    Eardley, A.4    Heller, G.5    Scheinberg, D.A.6
  • 34
    • 0030812198 scopus 로고    scopus 로고
    • Association of PML/RARα fusion mRNA type with pretreatment hematologic characteristics but not treatment outcome in acute promyelocytic leukemia: An intergroup molecular study
    • Gallagher R, Willman CL, Slack JL, Andersen JW, Li YP, Viswanatha D et al. Association of PML/RARα fusion mRNA type with pretreatment hematologic characteristics but not treatment outcome in acute promyelocytic leukemia: An intergroup molecular study. Blood 1997; 90: 1656-1663.
    • (1997) Blood , vol.90 , pp. 1656-1663
    • Gallagher, R.1    Willman, C.L.2    Slack, J.L.3    Andersen, J.W.4    Li, Y.P.5    Viswanatha, D.6
  • 35
    • 0036020954 scopus 로고    scopus 로고
    • FLT3 in human hematologic malignancies
    • Kiyoi H, Naoe T. FLT3 in human hematologic malignancies. Leuk Lymphoma 2002; 43: 1541-1547.
    • (2002) Leuk Lymphoma , vol.43 , pp. 1541-1547
    • Kiyoi, H.1    Naoe, T.2
  • 36
    • 10744230464 scopus 로고    scopus 로고
    • Biologic and clinical significance of the FLT3 transcript level in acute myeloid leukemia
    • Ozeki K, Kiyoi H, Hirose Y, Iwai M, Ninomiya M, Kodera Y et al. Biologic and clinical significance of the FLT3 transcript level in acute myeloid leukemia. Blood 2004; 103: 1901-1908.
    • (2004) Blood , vol.103 , pp. 1901-1908
    • Ozeki, K.1    Kiyoi, H.2    Hirose, Y.3    Iwai, M.4    Ninomiya, M.5    Kodera, Y.6
  • 37
    • 0036850573 scopus 로고    scopus 로고
    • Alterations of the FLT3 gene in acute promyelocytic leukemia: Association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol
    • Noguera NI, Breccia M, Divona M, Diverio D, Costa V, De Santis S et al. Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol. Leukemia 2002; 16: 2185-2189.
    • (2002) Leukemia , vol.16 , pp. 2185-2189
    • Noguera, N.I.1    Breccia, M.2    Divona, M.3    Diverio, D.4    Costa, V.5    De Santis, S.6
  • 38
    • 3142703726 scopus 로고    scopus 로고
    • FLT3-activating mutations are associated with poor prognostic features in AML at diagnosis but they are not an independent prognostic factor
    • Chillon MC, Fernandez C, Garcia-Sanz R, Balanzategui A, Ramos F, Fernandez-Calvo J et al. FLT3-activating mutations are associated with poor prognostic features in AML at diagnosis but they are not an independent prognostic factor. Hematol J 2004; 5: 239-246.
    • (2004) Hematol J , vol.5 , pp. 239-246
    • Chillon, M.C.1    Fernandez, C.2    Garcia-Sanz, R.3    Balanzategui, A.4    Ramos, F.5    Fernandez-Calvo, J.6
  • 39
    • 3142717007 scopus 로고    scopus 로고
    • FLT-3 aberrations in acute promyelocytic leukaemia: Clinicopathological associations and prognostic impact
    • Au WY, Fung A, Chim CS, Lie AK, Liang R, Ma ES et al. FLT-3 aberrations in acute promyelocytic leukaemia: Clinicopathological associations and prognostic impact. Br J Haematol 2004; 125: 463-469.
    • (2004) Br J Haematol , vol.125 , pp. 463-469
    • Au, W.Y.1    Fung, A.2    Chim, C.S.3    Lie, A.K.4    Liang, R.5    Ma, E.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.