The use of benzodiazepines in palliative care

Palliative Medicine

Volumn 20, Issue 4, 2006, Pages 407-412

  Henderson, Max ^a   MacGregor, E ^b   Sykes, N ^b   Hotopt, M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ST CHRISTOPHER S HOSPICE   (United Kingdom)

Author keywords

Anxiety; Benzodiazepines; Depression; Palliative care

Indexed keywords

ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; MIDAZOLAM; NEUROLEPTIC AGENT; OPIATE DERIVATIVE;

ADULT; AGED; ANXIETY; ARTICLE; CANCER MORTALITY; CANCER PALLIATIVE THERAPY; CONTROLLED STUDY; DEMOGRAPHY; DISTRESS SYNDROME; DRUG EFFICACY; DRUG INDICATION; DRUG USE; FEMALE; GENERAL PRACTITIONER; HOSPICE CARE; HOSPITAL DISCHARGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL DOCUMENTATION; MEDICAL RECORD; PRESCRIPTION; TERMINAL CARE; UNSPECIFIED SIDE EFFECT;

AGED; AGED, 80 AND OVER; BENZODIAZEPINES; FEMALE; HUMANS; MALE; MIDDLE AGED; PALLIATIVE CARE;

EID: 33746131701     PISSN: 02692163     EISSN: None     Source Type: Journal    
DOI: 10.1191/0269216306pm1151oa     Document Type: Article

References (24)

1. Committee on Safety of Medicines. Benzodiazepines, dependence and withdrawal symptoms. Committee on Safety of Medicines, 1998.
2. Lader MH. Limitations on the use of benzodiazepines in anxiety and insomnia: are they justified? Eur Neuropsychopharmacol 1999; 9: S399-405.
3. Michelini S, Cassano GB, Frare F, Perugi G. Long-term use of benzodiazepines: tolerance, dependence and clinical problems in anxiety and mood disorders. Pharmacopsychiatry 1996; 29: 127-34.
4. Marks IM, Swinson RP, Basoglu M, et al. Alprazolam and exposure alone and combined in panic disorder with agoraphobia. A controlled study in London and Toronto. Br J Psychiatry 1993; 162: 776-87.
5. Drummond SH, Peterson GM, Galloway JG, Keefe PA. National survey of drug use in palliative care. Palliat Med 1996; 10: 119-24.
6. Curtis E, Walsh TD. Prescribing practices of a palliative care service. J Pain Symptom Manage 1993; 8: 312-16.
7. Hoskin PJ, Hanks GW. The management of symptoms in advanced cancer: experience in a hospital-based continuing care unit. J R Soc Med 1988; 81: 341-44.
8. Sykes N, Thorns A. The use of opioids and sedatives at the end of life. Lancet Oncol 2003; 4: 312-18.
9. Radbruch L, Nauck F, Ostgathe C, et al. What are the problems in palliative care? Results from a representative survey. Support Care Cancer 2003; 11: 442-51.
10. Smith EM, Gomm SA, Dickens CM. Assessing the independent contribution to quality of life from anxiety and depression in patients with advanced cancer. Palliat Med 2003; 17: 509-13.
11. Hall S, Gallagher RM, Gracely E, Knowlton C, Wescules D. The terminal cancer patient: effects of age, gender, and primary tumor site on opioid dose. Pain Med 2003; 4: 125-34.
12. Rees WD. Opioid needs of terminal care patients: variations with age and primary site. Clin Oncol (R Coll Radiol) 1990; 2: 79-83.
13. Akechi T, Okamura H, Nishiwaki Y, Uchitomi Y. Psychiatric disorders and associated and predictive factors in patients with unresectable nonsmall cell lung carcinoma: a longitudinal study. Cancer 2001; 92: 2609-22.
14. Lloyd-Williams M. Is it appropriate to screen palliative care patients for depression? Am J Hosp Palliat Care 2002; 19: 112-14.
15. Norton TR, Manne SL, Rubin S, et al. Prevalence and predictors of psychological distress among women with ovarian cancer. J Clin Oncol 2004; 22: 919-26.
16. Rhodes VA, McDaniel RW. Nausea, vomiting, and retching: complex problems in palliative care. CA Cancer J Clin 2001; 51: 232-48.
17. Aizenberg D, Sigler M, Weizman A, Barak Y. Anticholinergic burden and the risk of falls among elderly psychiatric inpatients: a 4-year case-control study. Int Psychogeriatr 2002; 14: 307-10.
18. Department of Health. National Service framework for mental health. Department of Health, 1999.
19. Westra HA, Stewart SH. As-needed use of benzodiazepines in managing clinical anxiety: incidence and implications. Curr Pharm Des 2002; 8: 59-74.
20. Neutel CI, Perry S, Maxwell C. Medication use and risk of falls. Pharmacoepidemiol Drug Saf 2002; 11: 97-104.
21. Ensrud KE, Blackwell T, Mangione CM, et al. Central nervous system active medications and risk for fractures in older women. Arch Intern Med 2003; 163: 949-57.
22. Kunik ME, Braun U, Stanley MA, et al. One session cognitive behavioural therapy for elderly patients with chronic obstructive pulmonary disease. Psychol Med 2001; 31: 717-23.
23. Hotopf M, Chidgey J, Addington-Hall J, Ly KL. Depression in advanced disease: a systematic review part 1. Prevalence and case finding. Palliat Med 2002; 16: 81-97.
24. Flint AJ, Gagnon N. Diagnosis and management of panic disorder in older patients. Drug Aging 2003; 20: 881-91.