Cytokeratin and CD30 expression in dysgerminoma

Human Pathology

Volumn 37, Issue 8, 2006, Pages 1015-1021

  Cossu Rocca, Paolo ^a,b   Jones, Timothy D ^a   Roth, Lawrence M ^a   Eble, John N ^a   Zheng, Wenxin ^c   Abdul Karim, Fadi W ^d   Cheng, Liang ^a  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF SASSARI   (Italy)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

CD30; Dysgerminoma; E cadherin; Germ cell tumors; Histogenesis; Immunohistochemistry; Ovarian neoplasia

Indexed keywords

CD30 ANTIGEN; CELL ADHESION MOLECULE; CELL ADHESION MOLECULE 5.2; CYTOKERATIN; CYTOKERATIN 20; CYTOKERATIN 7; CYTOKERATIN AE1; CYTOKERATIN AE3; EPITHELIAL MEMBRANE ANTIGEN; FORMALDEHYDE; KERATIN; PARAFFIN; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; DYSGERMINOMA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; TISSUE FIXATION;

ADOLESCENT; ADULT; ANTIGENS, CD30; CELL COUNT; CHILD; DYSGERMINOMA; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; KERATINS; MIDDLE AGED; OVARIAN NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 33746087568     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2006.02.018     Document Type: Article

References (41)

1. Ulbright T.M. Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Mod Pathol 18 Suppl 2 (2005) S61-S79
2. Chen V.W., Ruiz B., Killeen J.L., Cote T.R., Wu X.C., and Correa C.N. Pathology and classification of ovarian tumors. Cancer 97 (2003) 2631-2642
3. Honecker F., Oosterhuis J.W., Mayer F., Hartmann J.T., Bokemeyer C., and Looijenga L.H. New insights into the pathology and molecular biology of human germ cell tumors. World J Urol 22 (2004) 15-24
4. Oosterhuis J.W., and Looijenga L.H. Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer 5 (2005) 210-222
5. Cheng L., Thomas A., Roth L.M., Zheng W., Michael H., and Karim F.W. OCT4: a novel biomarker for dysgerminoma of the ovary. Am J Surg Pathol 28 (2004) 1341-1346
6. Cheville J.C., Rao S., Iczkowski K.A., Lohse C.M., and Pankratz V.S. Cytokeratin expression in seminoma of the human testis. Am J Clin Pathol 113 (2000) 583-588
7. Davies B.R., Worsley S.D., and Ponder B.A. Expression of E-cadherin, alpha-catenin and beta-catenin in normal ovarian surface epithelium and epithelial ovarian cancers. Histopathology 32 (1998) 69-80
8. Honecker F., Kersemaekers A.M., Molier M., et al. Involvement of E-cadherin and beta-catenin in germ cell tumours and in normal male fetal germ cell development. J Pathol 204 (2004) 167-174
9. Suster S., Moran C.A., Dominguez-Malagon H., and Quevedo-Blanco P. Germ cell tumors of the mediastinum and testis: a comparative immunohistochemical study of 120 cases. Hum Pathol 29 (1998) 737-742
10. Van Niekerk C.C., Ramaekers F.C., Hanselaar A.G., Aldeweireldt J., and Poels L.G. Changes in expression of differentiation markers between normal ovarian cells and derived tumors. Am J Pathol 142 (1993) 157-177
11. Miettinen M., Wahlstrom T., Virtanen I., Talerman A., and Astengo-Osuna C. Cellular differentiation in ovarian sex-cord-stromal and germ-cell tumors studied with antibodies to intermediate-filament proteins. Am J Surg Pathol 9 (1985) 640-651
12. Parkash V., and Carcangiu M.L. Transformation of ovarian dysgerminoma to yolk sac tumor: evidence for a histogenetic continuum. Mod Pathol 8 (1995) 881-887
13. Miettinen M., Lehto V.P., and Virtanen I. Expression of intermediate filaments in normal ovaries and ovarian epithelial, sex cord-stromal, and germinal tumors. Int J Gynecol Pathol 2 (1983) 64-71
14. Spagnolo D.V., Michie S.A., Crabtree G.S., Warnke R.A., and Rouse R.V. Monoclonal anti-keratin (AE1) reactivity in routinely processed tissue from 166 human neoplasms. Am J Clin Pathol 84 (1985) 697-704
15. Lifschitz-Mercer B., Walt H., Kushnir I., et al. Differentiation potential of ovarian dysgerminoma: an immunohistochemical study of 15 cases. Hum Pathol 26 (1995) 62-66
16. Tickoo S.K., Hutchinson B., Bacik J., et al. Testicular seminoma: a clinicopathologic and immunohistochemical study of 105 cases with special reference to seminomas with atypical features. Int J Surg Pathol 10 (2002) 23-32
17. Moran C.A., Suster S., Przygodzki R.M., and Koss M.N. Primary germ cell tumors of the mediastinum: II. Mediastinal seminomas-a clinicopathologic and immunohistochemical study of 120 cases. Cancer 80 (1997) 691-698
18. Czaja J.T., and Ulbright T.M. Evidence for the transformation of seminoma to yolk sac tumor, with histogenetic considerations. Am J Clin Pathol 97 (1992) 468-477
19. Niehans G.A., Manivel J.C., Copland G.T., Scheithauer B.W., and Wick M.R. Immunohistochemistry of germ cell and trophoblastic neoplasms. Cancer 62 (1988) 1113-1123
20. Lifschitz-Mercer B., Fogel M., Moll R., et al. Intermediate filament protein profiles of human testicular non-seminomatous germ cell tumors: correlation of cytokeratin synthesis to cell differentiation. Differentiation 48 (1991) 191-198
21. Di Carlo A., and De Felici M. A role for E-cadherin in mouse primordial germ cell development. Dev Biol 226 (2000) 209-219
22. Heidenreich A., Sesterhenn I.A., Mostofi F.K., Moul J.W., and Engelmann U.H. Histopathologic and biological prognostic factors of clinical stage I non-seminomatous germ cell tumors. Implications for risk-adjusted therapy. Urologe A 38 (1999) 68-78
23. Saito T., Katagiri A., Watanabe R., et al. Expression of E-cadherin and catenins on testis tumor. Urol Int 65 (2000) 140-143
24. Baker P.M., and Oliva E. Immunohistochemistry as a tool in the differential diagnosis of ovarian tumors: an update. Int J Gynecol Pathol 24 (2005) 39-55
25. Hittmair A., Rogatsch H., Hobisch A., Mikuz G., and Feichtinger H. CD30 expression in seminoma. Hum Pathol 27 (1996) 1166-1171
26. Leroy X., Augusto D., and Leteurtre E. CD30 and CD117 (c-kit) used in combination are useful for distinguishing embryonal carcinoma from seminoma. J Histochem Cytochem 50 (2002) 283-285
27. Fogel M., Lifschitz-Mercer B., Moll R., et al. Heterogeneity of intermediate filament expression in human testicular seminomas. Differentiation 45 (1990) 242-249
28. Looijenga L.H.J., and Oosterhuis J.W. Pathogenesis of testicular germ cell tumours. Rev Reprod 4 (1999) 90-100
29. Atkin N.B., and Baker M.C. Abnormal chromosomes including small metacentrics in 14 ovarian cancers. Cancer Genet Cytogenet 26 (1987) 355-361
30. Bussey K.J., Lawce H.J., Himoe E., et al. Chromosomes 1 and 12 abnormalities in pediatric germ cell tumors by interphase fluorescence in situ hybridization. Cancer Genet Cytogenet 125 (2001) 112-118
31. Dal Cin P., Marynen P., Moerman P., Vergot I., and Van den Berghe H. Ovarian germ cell tumor with chromosome 12 anomaly but without i(12p). Cancer Genet Cytogenet 91 (1996) 61-64
32. Jenkyn D.J., and McCartney A.J. A chromosome study of three ovarian tumors. Cancer Genet Cytogenet 26 (1987) 327-337
33. Kraggerud S.M., Szymanska J., Abeler V.M., et al. DNA copy number changes in malignant ovarian germ cell tumors. Cancer Res 60 (2000) 3025-3030
34. Rodriguez E., Melamed J., Reuter V., and Chaganti R.S. Chromosome 12 abnormalities in malignant ovarian germ cell tumors. Cancer Genet Cytogenet 82 (1995) 62-66
35. Riopel M.A., Spellerberg A., Griffin C.A., and Perlman E.J. Genetic analysis of ovarian germ cell tumors by comparative genomic hybridization. Cancer Res 58 (1998) 3105-3110
36. Speleman F., De Potter C., Dal Cin P., et al. i(12p) in a malignant ovarian tumor. Cancer Genet Cytogenet 45 (1990) 49-53
37. Speleman F., Laureys G., Benoit Y., Cuvelier C., Suijkerbuijk R., and De Jong B. i(12p) in a near-diploid mature ovarian teratoma. Cancer Genet Cytogenet 60 (1992) 216-218
38. van Echten J., van Doorn L.C., van der Linden H.C., van der Veen A.Y., Burger C.W., and de Jong B. Cytogenetics of a malignant ovarian germ-cell tumor. Int J Cancer 77 (1998) 217-218
39. Culine S., Lhomme C., Kattan J., et al. Cisplatin-based chemotherapy in dysgerminoma of the ovary: thirteen-year experience at the Institut Gustave Roussy. Gynecol Oncol 58 (1995) 344-348
40. Williams S.D., Blessing J.A., Hatch K.D., and Homesley H.D. Chemotherapy of advanced dysgerminoma: trials of the Gynecologic Oncology Group. J Clin Oncol 9 (1991) 1950-1955
41. Looijenga L.H., Stoop H., de Leeuw H.P., et al. POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors. Cancer Res 63 (2003) 2244-2250