메뉴 건너뛰기




Volumn 152, Issue 7, 2006, Pages 1899-1911

Metabolic and regulatory engineering of Serratia marcescens: Mimicking phage-mediated horizontal acquisition of antibiotic biosynthesis and quorum-sensing capacities

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL PROTEIN; HOMOSERINE; LACTONE; PRODIGIOSIN;

EID: 33746049442     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.28803-0     Document Type: Article
Times cited : (70)

References (45)
  • 2
    • 0031757918 scopus 로고    scopus 로고
    • Antibiotic resistance and putative virulence factors of Serratia marcescens with respect to O and K serotypes
    • Aucken, H. M. & Pitt, T. L. (1998). Antibiotic resistance and putative virulence factors of Serratia marcescens with respect to O and K serotypes. J Med Microbiol 47, 1105-1113.
    • (1998) J Med Microbiol , vol.47 , pp. 1105-1113
    • Aucken, H.M.1    Pitt, T.L.2
  • 3
    • 0018932609 scopus 로고
    • Excretion of a protease by Serratia marcescens
    • Braun, V. & Schmitz, G. (1980). Excretion of a protease by Serratia marcescens. Arch Microbiol 124, 55-61.
    • (1980) Arch Microbiol , vol.124 , pp. 55-61
    • Braun, V.1    Schmitz, G.2
  • 4
    • 0027323312 scopus 로고
    • Enterobacterial hemolysins: Activation, secretion and pore formation
    • Braun, V., Schonherr, R. & Hobbie, S. (1993). Enterobacterial hemolysins: activation, secretion and pore formation. Trends Microbiol 1, 211-216.
    • (1993) Trends Microbiol , vol.1 , pp. 211-216
    • Braun, V.1    Schonherr, R.2    Hobbie, S.3
  • 5
    • 33645056466 scopus 로고    scopus 로고
    • Identification of the central quorum sensing regulator of virulence in the enteric phytopathogen, Erwinia carotovora: The VirR repressor
    • Burr, T., Barnard, A. M. L., Corbett, M. J., Pemberton, C. L., Simpson, N. J. L. & Salmond, G. P. C. (2006). Identification of the central quorum sensing regulator of virulence in the enteric phytopathogen, Erwinia carotovora: the VirR repressor. Mol Microbiol 59, 113-125.
    • (2006) Mol Microbiol , vol.59 , pp. 113-125
    • Burr, T.1    Barnard, A.M.L.2    Corbett, M.J.3    Pemberton, C.L.4    Simpson, N.J.L.5    Salmond, G.P.C.6
  • 6
    • 0017807890 scopus 로고
    • Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid
    • Chang, A. C. & Cohen, S. N. (1978). Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J Bacteriol 134, 1141-1156.
    • (1978) J Bacteriol , vol.134 , pp. 1141-1156
    • Chang, A.C.1    Cohen, S.N.2
  • 9
    • 2342662203 scopus 로고    scopus 로고
    • Characterization of monospecies biofilm formation by Helicobacter pylori
    • Cole, S. P., Harwood, J., Lee, R., She, R. & Guiney, D. G. (2004). Characterization of monospecies biofilm formation by Helicobacter pylori. J Bacteriol 186, 3124-3132.
    • (2004) J Bacteriol , vol.186 , pp. 3124-3132
    • Cole, S.P.1    Harwood, J.2    Lee, R.3    She, R.4    Guiney, D.G.5
  • 10
    • 3142745329 scopus 로고    scopus 로고
    • luxS mutants of Serratia defective in autoinducer-2-dependent 'quorum sensing' show strain-dependent impacts on virulence and production of carbapenem and prodigiosin
    • Coulthurst, S. J., Kurz, C. L. & Salmond, G. P. C. (2004). luxS mutants of Serratia defective in autoinducer-2-dependent 'quorum sensing' show strain-dependent impacts on virulence and production of carbapenem and prodigiosin. Microbiology 150, 1901-1910.
    • (2004) Microbiology , vol.150 , pp. 1901-1910
    • Coulthurst, S.J.1    Kurz, C.L.2    Salmond, G.P.C.3
  • 11
    • 33645107128 scopus 로고    scopus 로고
    • Genetic and proteomic analysis of the role of luxS in the enteric phytopathogen, Erwinia carotovora
    • Coulthurst, S. J., Lilley, K. S. & Salmond, G. P. C. (2006). Genetic and proteomic analysis of the role of luxS in the enteric phytopathogen, Erwinia carotovora. Mol Plant Pathol 7, 31-46.
    • (2006) Mol Plant Pathol , vol.7 , pp. 31-46
    • Coulthurst, S.J.1    Lilley, K.S.2    Salmond, G.P.C.3
  • 12
    • 0025195680 scopus 로고
    • Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in Gram-negative eubacteria
    • de Lorenzo, V., Herrero, M., Jakubzik, U. & Timmis, K. N. (1990). Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in Gram-negative eubacteria. J Bacteriol 172, 6568-6572.
    • (1990) J Bacteriol , vol.172 , pp. 6568-6572
    • de Lorenzo, V.1    Herrero, M.2    Jakubzik, U.3    Timmis, K.N.4
  • 13
    • 0029670074 scopus 로고    scopus 로고
    • Involvement of N-acyl-L-homoserine lactone autoinducers in controlling the multicellular behaviour of Serratia liquefaciens
    • & 7 other authors
    • Eberl, L., Winson, M. K., Sternberg, C. & 7 other authors (1996). Involvement of N-acyl-L-homoserine lactone autoinducers in controlling the multicellular behaviour of Serratia liquefaciens. Mol Microbiol 20, 127-136.
    • (1996) Mol Microbiol , vol.20 , pp. 127-136
    • Eberl, L.1    Winson, M.K.2    Sternberg, C.3
  • 14
    • 18444367148 scopus 로고    scopus 로고
    • Biosynthesis of tripyrrole and beta-lactam secondary metabolites in Serratia: Integration of quorum sensing with multiple new regulatory components in the control of prodigiosin and carbapenem antibiotic production
    • Fineran, P. C., Slater, H., Everson, L., Hughes, K. & Salmond, G. P. (2005). Biosynthesis of tripyrrole and beta-lactam secondary metabolites in Serratia: integration of quorum sensing with multiple new regulatory components in the control of prodigiosin and carbapenem antibiotic production. Mol Microbiol 56, 1495-1517.
    • (2005) Mol Microbiol , vol.56 , pp. 1495-1517
    • Fineran, P.C.1    Slater, H.2    Everson, L.3    Hughes, K.4    Salmond, G.P.5
  • 15
    • 10244250426 scopus 로고    scopus 로고
    • Synthesis and stability of small molecule probes for Pseudomonas aeruginosa quorum sensing modulation
    • Glansdorp, F. G., Thomas, G. L., Lee, J. K., Dutton, J. M., Salmond, G. P., Welch, M. & Spring, D. R. (2004). Synthesis and stability of small molecule probes for Pseudomonas aeruginosa quorum sensing modulation. Org Biomol Chem 2, 3329-3336.
    • (2004) Org Biomol Chem , vol.2 , pp. 3329-3336
    • Glansdorp, F.G.1    Thomas, G.L.2    Lee, J.K.3    Dutton, J.M.4    Salmond, G.P.5    Welch, M.6    Spring, D.R.7
  • 16
    • 0018424632 scopus 로고
    • Induction of luciferase synthesis in Beneckea harveyi by other marine bacteria
    • Greenberg, E. P., Hastings, J. W. & Ulitzer, S. (1979). Induction of luciferase synthesis in Beneckea harveyi by other marine bacteria. Arch Microbiol 120, 87-91.
    • (1979) Arch Microbiol , vol.120 , pp. 87-91
    • Greenberg, E.P.1    Hastings, J.W.2    Ulitzer, S.3
  • 18
    • 0029146378 scopus 로고
    • Bacteriocin 28b, a chromosomally encoded bacteriocin produced by most Serratia marcescens biotypes
    • Guasch, J. F., Enfedaque, J., Ferrer, S., Gargallo, D. & Regue, M. (1995). Bacteriocin 28b, a chromosomally encoded bacteriocin produced by most Serratia marcescens biotypes. Res Microbiol 146, 477-483.
    • (1995) Res Microbiol , vol.146 , pp. 477-483
    • Guasch, J.F.1    Enfedaque, J.2    Ferrer, S.3    Gargallo, D.4    Regue, M.5
  • 19
    • 9144222164 scopus 로고    scopus 로고
    • The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation
    • Harris, A. K., Williamson, N. R., Slater, H., Cox, A., Abbasi, S., Foulds, I., Simonsen, H. T., Leeper, F. J. & Salmond, G. P. (2004). The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation. Microbiology 150, 3547-3560.
    • (2004) Microbiology , vol.150 , pp. 3547-3560
    • Harris, A.K.1    Williamson, N.R.2    Slater, H.3    Cox, A.4    Abbasi, S.5    Foulds, I.6    Simonsen, H.T.7    Leeper, F.J.8    Salmond, G.P.9
  • 21
    • 0023774771 scopus 로고
    • Genetic analysis of extracellular proteins of Serratia marcescens
    • Hines, D. A., Saurugger, P. N., Ihler, G. M. & Benedik, M. J. (1988). Genetic analysis of extracellular proteins of Serratia marcescens. J Bacteriol 170, 4141-4146.
    • (1988) J Bacteriol , vol.170 , pp. 4141-4146
    • Hines, D.A.1    Saurugger, P.N.2    Ihler, G.M.3    Benedik, M.J.4
  • 22
    • 18644385349 scopus 로고    scopus 로고
    • The LuxR family protein SpnR functions as a negative regulator of N-acylhomoserine lactone-dependent quorum sensing in Serratia marcescens
    • & 7 other authors
    • Horng, Y. T., Deng, S. C., Daykin, M. & 7 other authors (2002). The LuxR family protein SpnR functions as a negative regulator of N-acylhomoserine lactone-dependent quorum sensing in Serratia marcescens. Mol Microbiol 45, 1655-1671.
    • (2002) Mol Microbiol , vol.45 , pp. 1655-1671
    • Horng, Y.T.1    Deng, S.C.2    Daykin, M.3
  • 23
    • 1642541008 scopus 로고    scopus 로고
    • Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1
    • Labbate, M., Queck, S. Y., Koh, K. S., Rice, S. A., Givskov, M. & Kjelleberg, S. (2004). Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. J Bacteriol 186, 692-698.
    • (2004) J Bacteriol , vol.186 , pp. 692-698
    • Labbate, M.1    Queck, S.Y.2    Koh, K.S.3    Rice, S.A.4    Givskov, M.5    Kjelleberg, S.6
  • 24
    • 3142681119 scopus 로고    scopus 로고
    • Regulatory circuits and communication in Gram-negative bacteria
    • Lazdunski, A. M., Ventre, I. & Sturgis, J. N. (2004). Regulatory circuits and communication in Gram-negative bacteria. Nat Rev Microbiol 2, 581-592.
    • (2004) Nat Rev Microbiol , vol.2 , pp. 581-592
    • Lazdunski, A.M.1    Ventre, I.2    Sturgis, J.N.3
  • 25
    • 0031755841 scopus 로고    scopus 로고
    • N-acyl-L-homoserine lactone autoinducers control production of an extracellular lipopeptide biosurfactant required for swarming motility of Serratia liquefaciens MG1
    • Lindum, P. W., Anthoni, U., Christophersen, C., Eberl, L., Molin, S. & Givskov, M. (1998). N-acyl-L-homoserine lactone autoinducers control production of an extracellular lipopeptide biosurfactant required for swarming motility of Serratia liquefaciens MG1. J Bacteriol 180, 6384-6388.
    • (1998) J Bacteriol , vol.180 , pp. 6384-6388
    • Lindum, P.W.1    Anthoni, U.2    Christophersen, C.3    Eberl, L.4    Molin, S.5    Givskov, M.6
  • 26
    • 0028869728 scopus 로고
    • Mutational analysis of flagellum-independent surface spreading of Serratia marcescens 274 on a low-agar medium
    • Matsuyama, T., Bhasin, A. & Harshey, R. M. (1995). Mutational analysis of flagellum-independent surface spreading of Serratia marcescens 274 on a low-agar medium. J Bacteriol 177, 987-991.
    • (1995) J Bacteriol , vol.177 , pp. 987-991
    • Matsuyama, T.1    Bhasin, A.2    Harshey, R.M.3
  • 27
    • 0031467411 scopus 로고    scopus 로고
    • Quorum sensing and Chromobacterium violaceum: Exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones
    • & 9 other authors
    • McClean, K. H., Winson, M. K., Fish, L. & 9 other authors (1997). Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones. Microbiology 143, 3703-3711.
    • (1997) Microbiology , vol.143 , pp. 3703-3711
    • McClean, K.H.1    Winson, M.K.2    Fish, L.3
  • 28
    • 0037379038 scopus 로고    scopus 로고
    • Mutation of luxS affects biofilm formation in Streptococcus mutans
    • Merritt, J., Qi, F., Goodman, S. D., Anderson, M. H. & Shi, W. (2003). Mutation of luxS affects biofilm formation in Streptococcus mutans. Infect Immun 71, 1972-1979.
    • (2003) Infect Immun , vol.71 , pp. 1972-1979
    • Merritt, J.1    Qi, F.2    Goodman, S.D.3    Anderson, M.H.4    Shi, W.5
  • 29
    • 0036016826 scopus 로고    scopus 로고
    • The autoregulatory role of EsaR, a quorum-sensing regulator in Pantoea stewartii ssp. stewartii: Evidence for a repressor function
    • Minogue, T. D., Wehland-von Trebra, M., Bernhard, F. & von Bodman, S. B. (2002). The autoregulatory role of EsaR, a quorum-sensing regulator in Pantoea stewartii ssp. stewartii: evidence for a repressor function. Mol Microbiol 44, 1625-1635.
    • (2002) Mol Microbiol , vol.44 , pp. 1625-1635
    • Minogue, T.D.1    Wehland-von Trebra, M.2    Bernhard, F.3    von Bodman, S.B.4
  • 30
    • 16244403932 scopus 로고    scopus 로고
    • The cell density-dependent expression of stewartan exopolysaccharide in Pantoea stewartii ssp. stewartii is a function of EsaR-mediated repression of the rcsA gene
    • Minogue, T. D., Carlier, A. L., Koutsoudis, M. D. & von Bodman, S. B. (2005). The cell density-dependent expression of stewartan exopolysaccharide in Pantoea stewartii ssp. stewartii is a function of EsaR-mediated repression of the rcsA gene. Mol Microbiol 56, 189-203.
    • (2005) Mol Microbiol , vol.56 , pp. 189-203
    • Minogue, T.D.1    Carlier, A.L.2    Koutsoudis, M.D.3    von Bodman, S.B.4
  • 31
    • 3843091794 scopus 로고    scopus 로고
    • Chemical communication in proteobacteria: Biochemical and structural studies of signal synthases and receptors required for intercellular signalling
    • Pappas, K. M., Weingart, C. L. & Winans, S. C. (2004). Chemical communication in proteobacteria: biochemical and structural studies of signal synthases and receptors required for intercellular signalling. Mol Microbiol 53, 755-769.
    • (2004) Mol Microbiol , vol.53 , pp. 755-769
    • Pappas, K.M.1    Weingart, C.L.2    Winans, S.C.3
  • 32
    • 18244395069 scopus 로고    scopus 로고
    • Biofilm formation and sloughing in Serratia marcescens are controlled by quorum sensing and nutrient cues
    • Rice, S. A., Koh, K. S., Queck, S. Y., Labbate, M., Lam, K. W. & Kjelleberg, S. (2005). Biofilm formation and sloughing in Serratia marcescens are controlled by quorum sensing and nutrient cues. J Bacteriol 187, 3477-3485.
    • (2005) J Bacteriol , vol.187 , pp. 3477-3485
    • Rice, S.A.1    Koh, K.S.2    Queck, S.Y.3    Labbate, M.4    Lam, K.W.5    Kjelleberg, S.6
  • 33
    • 0035116865 scopus 로고    scopus 로고
    • N-acyl-L-homoserine lactone-mediated regulation of the lip secretion system in Serratia liquefaciens MG1
    • Riedel, K., Ohnesorg, T., Krogfelt, K. A., Hansen, T. S., Omori, K., Givskov, M. & Eberl, L. (2001). N-acyl-L-homoserine lactone-mediated regulation of the lip secretion system in Serratia liquefaciens MG1. J Bacteriol 183, 1805-1809.
    • (2001) J Bacteriol , vol.183 , pp. 1805-1809
    • Riedel, K.1    Ohnesorg, T.2    Krogfelt, K.A.3    Hansen, T.S.4    Omori, K.5    Givskov, M.6    Eberl, L.7
  • 35
    • 0024842848 scopus 로고
    • Genome walking by single-specific-primer polymerase chain reaction: SSP-PCR
    • Shyamala, V. & Ames, G. F. (1989). Genome walking by single-specific-primer polymerase chain reaction: SSP-PCR. Gene 84, 1-8.
    • (1989) Gene , vol.84 , pp. 1-8
    • Shyamala, V.1    Ames, G.F.2
  • 36
    • 0037244560 scopus 로고    scopus 로고
    • Phosphate availability regulates biosynthesis of two antibiotics, prodigiosin and carbapenem, in Serratia via both quorum-sensing-dependent and -independent pathways
    • Slater, H., Crow, M., Everson, L. & Salmond, G. P. (2003). Phosphate availability regulates biosynthesis of two antibiotics, prodigiosin and carbapenem, in Serratia via both quorum-sensing-dependent and -independent pathways. Mol Microbiol 47, 303-320.
    • (2003) Mol Microbiol , vol.47 , pp. 303-320
    • Slater, H.1    Crow, M.2    Everson, L.3    Salmond, G.P.4
  • 37
    • 0030158571 scopus 로고    scopus 로고
    • The Staden sequence analysis package
    • Staden, R. (1996). The Staden sequence analysis package. Mol Biotechnol 5, 233-241.
    • (1996) Mol Biotechnol , vol.5 , pp. 233-241
    • Staden, R.1
  • 38
    • 0032499746 scopus 로고    scopus 로고
    • Quorum sensing in Escherichia coli and Salmonella typhimurium
    • Surette, M. G. & Bassler, B. L, (1998). Quorum sensing in Escherichia coli and Salmonella typhimurium. Proc Natl Acad Sci U S A 95, 7046-7050.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7046-7050
    • Surette, M.G.1    Bassler, B.L.2
  • 39
    • 0033574064 scopus 로고    scopus 로고
    • Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: A new family of genes responsible for autoinducer production
    • Surette, M. G., Miller, M. B. & Bassler, B. L. (1999). Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: a new family of genes responsible for autoinducer production. Proc Natl Acad Sci U S A 96, 1639-1644.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 1639-1644
    • Surette, M.G.1    Miller, M.B.2    Bassler, B.L.3
  • 40
    • 0034016854 scopus 로고    scopus 로고
    • Biosynthesis of carbapenem antibiotic and prodigiosin pigment in Serratia is under quorum sensing control
    • Thomson, N. R., Crow, M. A., McGowan, S. J., Cox, A. & Salmond, G. P. (2000). Biosynthesis of carbapenem antibiotic and prodigiosin pigment in Serratia is under quorum sensing control. Mol Microbiol 36, 539-556.
    • (2000) Mol Microbiol , vol.36 , pp. 539-556
    • Thomson, N.R.1    Crow, M.A.2    McGowan, S.J.3    Cox, A.4    Salmond, G.P.5
  • 41
    • 17844389564 scopus 로고    scopus 로고
    • Making 'sense' of metabolism: Autoinducer-2, LuxS and pathogenic bacteria
    • Vendeville, A., Winzer, K., Heurlier, K., Tang, C. M. & Hardie, K. R. (2005). Making 'sense' of metabolism: autoinducer-2, LuxS and pathogenic bacteria. Nat Rev Microbiol 3, 383-396.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 383-396
    • Vendeville, A.1    Winzer, K.2    Heurlier, K.3    Tang, C.M.4    Hardie, K.R.5
  • 43
    • 18444391489 scopus 로고    scopus 로고
    • Biosynthesis of the red antibiotic, prodigiosin, in Serratia: Identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces
    • Williamson, N. R., Simonsen, H. T., Ahmed, R. A., Goldet, G., Slater, H., Woodley, L., Leeper, F. J. & Salmond, G. P. (2005). Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces. Mol Microbiol 56, 971-989.
    • (2005) Mol Microbiol , vol.56 , pp. 971-989
    • Williamson, N.R.1    Simonsen, H.T.2    Ahmed, R.A.3    Goldet, G.4    Slater, H.5    Woodley, L.6    Leeper, F.J.7    Salmond, G.P.8
  • 44
    • 30844473318 scopus 로고    scopus 로고
    • Disruption of the copper efflux pump (CopA) of Serratia marcescens ATCC274 pleiotropically affects copper sensitivity and production of the tripyrrole secondary metabolite, prodigiosin
    • Williamson, N. R., Simonsen, H. T., Harris, A. K., Leeper, F. J. & Salmond, G. P. (2006). Disruption of the copper efflux pump (CopA) of Serratia marcescens ATCC274 pleiotropically affects copper sensitivity and production of the tripyrrole secondary metabolite, prodigiosin. J Ind Microbiol Biotechnol 33, 151-158.
    • (2006) J Ind Microbiol Biotechnol , vol.33 , pp. 151-158
    • Williamson, N.R.1    Simonsen, H.T.2    Harris, A.K.3    Leeper, F.J.4    Salmond, G.P.5
  • 45
    • 0036224825 scopus 로고    scopus 로고
    • LuxS: Its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone
    • & 8 other authors
    • Winzer, K., Hardie, K. R., Burgess, N. & 8 other authors (2002). LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone. Microbiology 148, 909-922.
    • (2002) Microbiology , vol.148 , pp. 909-922
    • Winzer, K.1    Hardie, K.R.2    Burgess, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.