Coenzyme Q10 supplementation reduces corticosteroids dosage in patients with bronchial asthma

BioFactors

Volumn 25, Issue 1-4, 2005, Pages 235-240

  Gvozdjáková, Anna ^a   Kucharská, Jarmila ^a   Bartkovjaková, Mária ^a   Gazdíková, Katarína ^b   Gazdík, František ^b  

^a Physics and Informatics   (Slovakia)

^b SLOVAK MEDICAL UNIVERSITY   (Slovakia)

Author keywords

Bronchial asthma; Coenzyme Q10; Corticosteroids; DNA; Oxidative stress

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; Q GEL; UBIDECARENONE; DRUG DERIVATIVE; UBIQUINONE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ASTHMA; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG TISSUE LEVEL; DRUG UPTAKE; FEMALE; HUMAN; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RAT; SUPPLEMENTATION; TREATMENT DURATION; ANIMAL; ARTICLE; BLOOD; LUNG; METABOLISM; MIDDLE AGED; MITOCHONDRION; WISTAR RAT;

ADRENAL CORTEX HORMONES; ADULT; ALPHA-TOCOPHEROL; ANIMALS; ASCORBIC ACID; ASTHMA; CROSS-OVER STUDIES; FEMALE; HUMANS; LUNG; MALE; MIDDLE AGED; MITOCHONDRIA; RATS; RATS, WISTAR; UBIQUINONE;

EID: 33746047120     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520250129     Document Type: Conference Paper

References (12)

1. S.J. Gardai, R. Hoontrakoon, C.D. Goddard, B.J. Day, L.Y. Chang, P.M. Henson and D.L. Bratton, Oxidant-mediated mitochondrial injury in eosinophil apoptosis: Enhancement by glucocorticosteroids and inhibition by granulocyte-macrophage colony-stimulating factor, J Immunol 170 (2003), 556-566.
2. 10 in patients with bronchial asthma, Allergy 57 (2002), 811-814.
3. 10 Association, Abstract book, 2005, 108-109.
4. D.R. Janero and B. Burghardt, Thiobarbituric acid-reactive malondialdehyde formation during superoxide-dependent iron-catalyzed lipid peroxidation: influence of peroxidation conditions, Lipids 24 (1989), 125-131.
5. V.L. Kinnula, Production and degradation of oxygen metabolites during inflammatory states in the human lung, Curr Drug Targets Inflamm Allergy 4/4 (2005), 465-470.
6. J.K. Lang, K. Gohil and L. Packer, Simultaneous determination of tocopherols, ubiquinols and ubiquinones in blood, plasma, tissue homogenates, and subcellular fractions, Analytical Biochemistry 157 (1986), 106-116.
7. 10, gene expression and metabolic regulation, Mitochondrion 4/5-6 (2004), 779-789.
8. N.L. Misso, J. Brooks-Wildhaber, S. Ray, H. Vally and P.J. Thompson, Plasma concentrations of dietary and nondietary antioxidants are low in severe asthma, Eur Respir J. 26/2 (2005), 257-264.
9. T. Mitsui, H. Azuma, M. Nagasawa, T. Iuchi, M. Akaike, M. Odomi and T. Matsumoto, Chronic corticosteroid administration causes mitochondrial dysfunction in skeletal muscle, J Neurol. 249/8 (2002), 1004-1009.
10. T. Mitsui, Z. Umaki, M. Nagasawa, M. Akaike, K. Aki, H. Azuma, S. Ozaki, M. Odomi and T. Matsumoto, Mitochondrial damage in patients with long-term corticosteroid therapy: development of oculoskeletal symptoms similar to mitochondrial disease, Acta Neuropathol 104/3 (2002), 260-266.
11. K.R. Shanmugasundaram, S.S. Kumar and S. Rajajee, Excessive free radical generation in the blood of children suffering from asthma, Clin Chim Acta 305 (2001), 107-114.
12. H. Vural, N. Aksoy, E. Ceylan, M. Gencer and F. Ozguner, Leukocyte oxidant and antioxidant status in asthmatic patients, Arch Med Res 36/5 (2005), 502-506.