Calcium spikes in basal dendrites of layer 5 pyramidal neurons during action potential bursts

Journal of Neuroscience

Volumn 26, Issue 28, 2006, Pages 7424-7432

  Kampa, Björn M ^a,b   Stuart, Greg J ^a  

^a Biology and Environment   (Australia)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Action potential; Backpropagation; Dendrite; Imaging; Neocortex; STDP

Indexed keywords

CALCIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POTASSIUM CHANNEL; SODIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITE; MOUSE; NERVE CELL PLASTICITY; NERVE EXCITABILITY; NERVE POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PYRAMIDAL NERVE CELL; SIGNAL TRANSDUCTION; SIMULATION; SPIKE WAVE; ANIMAL; CELL POLARITY; DRUG POTENTIATION; EXCITATORY POSTSYNAPTIC POTENTIAL; IN VITRO STUDY; PHYSIOLOGY; RAT; SYNAPSE; WISTAR RAT;

ACTION POTENTIALS; ANIMALS; CALCIUM; CELL POLARITY; DENDRITES; EXCITATORY POSTSYNAPTIC POTENTIALS; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES;

EID: 33746039343     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3062-05.2006     Document Type: Article

References (43)

1. Antic SD (2003) Action potentials in basal and oblique dendrites of rat neocortical pyramidal neurons. J Physiol (Lond) 550:35-50.
2. Bekkers JM (2000) Distribution and activation of voltage-gated potassium channels in cell-attached and outside-out patches from large layer 5 cortical pyramidal neurons of the rat. J Physiol (Lond) 525:611-620.
3. Bi G-Q, Poo M-M (1998) Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type. J Neurosci 18:10464-10472.
4. Bliss TV, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31-39.
5. Denk W, Yuste R, Svoboda K, Tank DW (1996) Imaging calcium dynamics in dendritic spines. Curr Opin Neurobiol 6:372-378.
6. 2+ signals by small oblique dendrites of CA1 pyramidal neurons. J Neurosci 23:3243-3250.
7. Hell JW, Westenbroek RE, Warner C, Ahlijanian MK, Prystay W, Gilbert MM, Snutch TP, Catterall WA (1993) Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunits. J Cell Biol 123:949-962.
8. 2+ signaling in dendrites of pyramidal neurons. Biophys J 70:1069-1081.
9. Hines ML, Carnevale NT (1997) The NEURON simulation environment. Neural Comput 9:1179-1209.
10. + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 387:869-875.
11. Kampa B, Letzkus JJ, Stuart GJ (2006) Requirement of dendritic calcium spikes for induction of spike-timing dependent synaptic plasticity. J Physiol (Lond) 574.1:283-290.
12. Korngreen A, Sakmann B (2000) Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats: subtypes and gradients. J Physiol (Lond) 525:621-639.
13. Larkman AU (1991) Dendritic morphology of pyramidal neurones of the visual cortex of the rat. III. Spine distributions. J Comp Neurol 306:332-343.
14. Larkum ME, Kaiser KM, Sakmann B (1999) Calcium electrogenesis in distal apical dendrites of layer 5 pyramidal cells at a critical frequency of back-propagating action potentials. Proc Natl Acad Sci USA 96:14600-14604.
15. Lisman JE (1997) Bursts as a unit of neural information: making unreliable synapses reliable. Trends Neurosci 20:38-43.
16. Magee JC, Johnston D (1997) A synaptically controlled, associative signal for Hebbian plasticity in hippocampal neurons. Science 275:209-213.
17. Markram H, Lübke J, Frotscher M, Sakmann B (1997a) Regulation of synaptic efficacy by coincidence of postsynaptic APs and EPSPs. Science 275:213-215.
18. Markram H, Lubke J, Frotscher M, Roth A, Sakmann B (1997b) Physiology and anatomy of synaptic connections between thick tufted pyramidal neurones in the developing rat neocortex. J Physiol (Lond) 500:409-440.
19. + conductance in the back-propagation of action potentials in the dendrites of hippocampal pyramidal neurons. J Comput Neurosci 7:5-15.
20. Milojkovic BA, Radojicic MS, Goldman-Rakic PS, Antic SD (2004) Burst generation in rat pyramidal neurones by regenerative potentials elicited in a restricted part of the basilar dendritic tree. J Physiol (Lond) 558:193-211.
21. Paulsen O, Sejnowski TJ (2000) Natural patterns of activity and long-term synaptic plasticity. Curr Opin Neurobiol 10:172-179.
22. Pike FG, Meredith RM, Olding AW, Paulsen O (1999) Postsynaptic bursting is essential for "Hebbian" induction of associative long-term potentiation at excitatory synapses in rat hippocampus. J Physiol (Lond) 518:571-576.
23. Polsky A, Mel BW, Schiller J (2004) Computational subunits in thin dendrites of pyramidal cells. Nat Neurosci 7:621-627.
24. 2+ ions in dendritic spines. Neuron 33:439-452.
25. Schaefer AT, Larkum ME, Sakmann B, Roth A (2003) Coincidence detection in pyramidal neurons is tuned by their dendritic branching pattern. J Neurophysiol 89:3143-3154.
26. Schiller J, Schiller Y, Stuart G, Sakmann B (1997) Calcium action potentials restricted to distal apical dendrites of rat neocortical pyramidal neurons. J Physiol (Lond) 505:605-616.
27. Schiller J, Schiller Y, Clapham DE (1998) NMDA receptors amplify calcium influx into dendritic spines during associative pre- and postsynaptic activation. Nat Neurosci 1:114-118.
28. Schiller J, Major G, Koester HJ, Schiller Y (2000) NMDA spikes in basal dendrites of cortical pyramidal neurons. Nature 404:285-289.
29. Sjostrom PJ, Turrigiano GG, Nelson SB (2001) Rate, timing, and cooperativity jointly determine cortical synaptic plasticity. Neuron 32:1149-1164.
30. Sjostrom PJ, Turrigiano GG, Nelson SB (2003) Neocortical LTD via coincident activation of presynaptic NMDA and cannabinoid receptors. Neuron 39:641-654.
31. Snider RK, Kabara JF, Roig BR, Bonds AB (1998) Burst firing and modulation of functional connectivity in cat striate cortex. J Neurophysiol 80:730-744.
32. Spruston N, Jaffe DB, Williams SH, Johnston D (1993) Voltage- and space-clamp errors associated with the measurement of electrotonically remote synaptic events. J Neurophysiol 70:781-802.
33. Stuart G, Spruston N (1998) Determinants of voltage attenuation in neocortical pyramidal neuron dendrites. J Neurosci 18:3501-3510.
34. Stuart G, Spruston N, Sakmann B, Häusser M (1997) Action potential initiation and backpropagation in neurons of the mammalian central nervous system. Trends Neurosci 20:125-131.
35. Stuart GJ, Hausser M (2001) Dendritic coincidence detection of EPSPs and action potentials. Nat Neurosci 4:63-71.
36. Stuart GJ, Sakmann B (1994) Active propagation of somatic action potentials into neocortical pyramidal cell dendrites. Nature 367:69-72.
37. Thomas MJ, Watabe AM, Moody TD, Makhinson M, O'Dell TJ (1998) Postsynaptic complex spike bursting enables the induction of LTP by theta frequency synaptic stimulation. J Neurosci 18:7118-7126.
38. Tsien RY (1989) Fluorescent probes of cell signaling. Annu Rev Neurosci 12:227-253.
39. 2+ unblock of NMDA receptors limits their contribution to spike generation in cortical pyramidal neurons. J Neurophysiol 89:2778-2783.
40. Vetter P, Roth A, Hausser M (2001) Propagation of action potentials in dendrites depends on dendritic morphology. J Neurophysiol 85:926-937.
41. Westenbroek RE, Hell JW, Warner C, Dubel SJ, Snutch TP, Catterall WA (1992) Biochemical properties and subcellular distribution of an N-type calcium channel alpha 1 subunit. Neuron 9:1099-1115.
42. Westenbroek RE, Sakurai T, Elliott EM, Hell JW, Starr TV, Snutch TP, Catterall WA (1995) Immunochemical identification and subcellular distribution of the α1A subunits of brain calcium channels. J Neurosci 15:6403-6418.
43. Williams SR, Stuart GJ (2000) Backpropagation of physiological spike trains in neocortical pyramidal neurons: implications for temporal coding in dendrites. J Neurosci 20:8238-8246.