Alert and sniffy-nosed about Mll-AF4?

Blood

Volumn 108, Issue 2, 2006, Pages 416-417

  Greaves, Mel ^a   So, C W Eric ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MIXED LINEAGE LEUKEMIA PROTEIN;

ALERTNESS; B LYMPHOCYTE; BONE MARROW CELL; CELL LINEAGE; FUSION GENE; GENETIC ENGINEERING; GENOTOXICITY; HUMAN; IN VITRO STUDY; LEUKEMOGENESIS; LYMPHATIC LEUKEMIA; LYMPHOID CELL; MLL AF4 GENE; MOLECULAR CLONING; MUTATION RATE; NONHUMAN; NOTE; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SNIFFING; STEM CELL;

EID: 33745968731     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-05-019539     Document Type: Note

References (7)

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3. Forster A, Pannell R, Drynan LF, et al. Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer. Cancer Cell. 2003;3:449-458.
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5. Metzler M, Forster A, Pannell R, et al. A conditional model of MLL-AF4 B-cell tumourigenesis using invertor technology. Oncogene. Prepublished online April 10, 2006, as DOI:10.1038/sj.onc.120936.
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7. Eguchi M, Eguchi-Ishimae M, Knight D, Kearney L, Slany R, Greaves M.MLLchimeric protein activation renders cells vulnerable to chromosomal damage: an explanation for the very short latency of infant leukemia. Genes Chromosomes Cancer. 2006;45:754-760.