Ocular toxicity of systemic asthma and allergy treatments

Current Allergy and Asthma Reports

Volumn 6, Issue 4, 2006, Pages 299-305

  Bielory, Leonard ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIALLERGIC AGENT; ANTIASTHMATIC AGENT; ANTIHISTAMINIC AGENT; ANTIINFLAMMATORY AGENT; ASTEMIZOLE; BECLOMETASONE DIPROPIONATE; BUDESONIDE; CETIRIZINE; CHLORPHENIRAMINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; CROMOGLYCATE DISODIUM; DESLORATADINE; DIPHENHYDRAMINE; FLUNISOLIDE; FLUTICASONE PROPIONATE; LORATADINE; NEDOCROMIL; PLACEBO; PREDNISONE; TERFENADINE;

CARDIOVASCULAR DISEASE; CATARACT; CLINICAL TRIAL; CONJUNCTIVA DISEASE; DISEASE EXACERBATION; DISEASE PREDISPOSITION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG INDUCED DISEASE; DRUG INDUCED HEADACHE; DRY EYE; EYE ALLERGY; EYE TOXICITY; GLAUCOMA; GROWTH RETARDATION; HUMAN; IMMUNOPATHOLOGY; INTRAOCULAR HYPERTENSION; METABOLIC DISORDER; MUSCULOSKELETAL DISEASE; NASAL PRURITUS; NONHUMAN; NOSE CONGESTION; OCULAR PRURITUS; OPEN ANGLE GLAUCOMA; REVIEW; RHINORRHEA; SEDATION; SKIN TOXICITY; SNEEZING; SOMNOLENCE; SUBCAPSULAR CATARACT; TEAR FILM;

ADRENAL CORTEX HORMONES; ANTI-ASTHMATIC AGENTS; ASTHMA; DRY EYE SYNDROMES; EYE DISEASES; HISTAMINE ANTAGONISTS; HUMANS;

EID: 33745964586     PISSN: 15297322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11882-006-0063-y     Document Type: Review

References (51)

1. Allen DB, Bielory L, Derendorf H, et al.: Inhaled corticosteroids: past lessons and future issues. J Allergy Clin Immunol 2003, 112:S1-S40.
2. Kewley GD: Possible association between beclomethasone diproprionate aerosol and cataracts. Aust Paediatr J 1980, 16:117-118.
3. Black R, Oglesby R, von Sallmann L, Bunim J: Posterior subcapsular cataracts induced by corticosteroids in patients with rheumatoid arthritis. JAMA 1960, 174:150-171.
4. Bhagat RG, Chai H: Development of posterior subcapsular cataracts in asthmatic children. Pediatrics 1984, 73:626-630.
5. Rooklin A, Lampert S, Jaeger E, et al.: Posterior subcapsular cataracts in steroid requiring asthmatic children. J Allergy Clin Immunol 1979, 63:383-386.
6. Urban R, Cotlier E: Corticosteroid induced cataracts. Surv Ophthalmol 1986, 31:102-110.
7. Forman AR, Loreto JA, Tina LU: Reversibility of corticosteroid-associated cataracts in children with the nephrotic syndrome. Am J Ophthalmol 1977, 84:75-78.
8. Oglesby R, Black R, von Sallmarm L, Bunim J: Cataracts in patients with rheumatic diseases treated with corticosteroids. Arch Ophthalmol 1961, 66:41-46.
9. Nassif E, Weinberger M, Sherman B, Brown K: Extrapulmonary effects of maintenance corticosteroid therapy with alternate-day prednisone and inhaled beclomethasone in children with chronic asthma. J Allergy Clin Immunol 1987, 80:518-529.
10. Toogood JH, Markov AE, Baskerville J, Dyson C: Association of ocular cataracts with inhaled and oral steroid therapy during long-term treatment of asthma. J Allergy Clin Immunol 1993, 91:571-579.
11. Simons FE, Persaud MP, Gillespie CA, et al.: Absence of posterior subcapsular cataracts in young patients treated with inhaled glucocorticoids. Lancet 1993, 342:776-778.
12. Russell G: Inhaled corticosteroid therapy in children: an assessment of the potential for side effects. Thorax 1994, 49:1185-1188.
13. Cumming R, Mitchell P, Leeder S: Use of inhaled corticosteroids and the risk of cataracts. N Engl J Med 1997, 337:8-14.
14. Garbe E, Suissa S, LeLorier J:. Association of inhaled corticosteroid use with cataract extraction in elderly patients. JAMA 1998, 280:539-543.
15. Hanania NA, Chapman KR, Kesten S: Adverse effects of inhaled corticosteroids. Am J Med 1995, 98:196-208.
16. Dluhy RG: Effect of inhaled beclomethasone dipropionate and budesonide on adrenal function, skin changes and cataract formation. Respir Med 1998, 92(Suppl B):15-23.
17. Agertoft L, Larsen FE, Pedersen S: Posterior subcapsular cataracts, bruises and hoarseness in children with asthma receiving long-term treatment with inhaled budesonide. Eur Respir J 1998, 12:130-135.
18. Long-term effects of budesonide or nedocromil in children with asthma. The Childhood Asthma Management Program Research Group. N Engl J Med 2000, 343:1054-1063.
19. Moller C, Ahlstrom H, Henricson KA, et al.: Safety of nasal budesonide in the long-term treatment of children with perennial rhinitis. Clin Exp Allergy 2003, 33:816-822.
20. Jick SS, Vasilakis-Scaramozza C, Maier WC: The risk of cataract among users of inhaled steroids. Epidemiology 2001, 12:229-234.
21. Bisgaard H, Allen D, Milanowski J, et al.: Twelve-month safety and efficacy of inhaled fluticasone propionate in children aged 1 to 3 years with recurrent wheezing. Pediatrics 2004, 113:e87-e94.
22. Sheffer AL, Silverman M, Woolcock AJ, et al.: Long-term safety of once-daily budesonide in patients with early-onset mild persistent asthma: results of the Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) study. Ann Allergy Asthma Immunol 2005, 94:48-54.
23. Tripathi RC, Parapuram SK, Tripathi BJ, et al.: Corticosteroids and glaucoma risk. Drugs Aging 1999, 15:439-450.
24. Zhang X, Clark AF, Yorio T: Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-beta. Invest Ophthalmol Vis Sci 2005, 46:4607-4616.
25. Stokes J, Walker BR, Campbell JC, et al.: Altered peripheral sensitivity to glucocorticoids in primary open-angle glaucoma. Invest Ophthalmol Vis Sci 2003, 44:5163-5167.
26. Dreyer EB: Inhaled steroid use and glaucoma. N Engl J Med 1993, 329:1822.
27. Opatowsky I, Feldman RM, Gross R, Feldman ST: Intraocular pressure elevation associated with inhalation and nasal corticosteroids. Ophthalmology 1995, 102:177-179.
28. Desnoeck M, Casteels I, Casteels K: Intraocular pressure elevation in a child due to the use of inhalation steroids - a case report. Bull Soc Belge Ophtalmol 2001, 280:97-100.
29. Hartung J, Knapp G: [A re-analysis of the Blue Mountain eye study on the risk of cataracts from inhaled corticosteroids. A contribution to objectifying the discussion]. Pneumologie 1999, 53:411-416.
30. Garbe E, LeLorier J, Boivin JF, Suissa S: Inhaled and nasal glucocorticoids and the risks of ocular hypertension or open-angle glaucoma. JAMA 1997, 277:722-727.
31. Behbehani AH, Owayed AF, Hijazi ZM, et al.: Cataract and ocular hypertension in children on inhaled corticosteroid therapy. J Pediatr Ophthalmol Strabismus 2005, 42:23-27.
32. Duh MS, Walker AM, Lindmark B, Laties AM: Association between intraocular pressure and budesonide inhalation therapy in asthmatic patients. Ann Allergy Asthma Immunol 2000, 85:356-361.
33. Dibildox J:. Safety and efficacy of mometasone furoate aqueous nasal spray in children with allergic rhinitis: results of recent clinical trials. J Allergy Clin Immunol 2001, 108(1 Suppl):S54-S58.
34. Tripathi RC, Kipp MA, Tripathi BJ, et al.: Ocular toxicity of prednisone in pediatric patients with inflammatory bowel disease. Lens Eye Toxic Res 1992, 9:469-482.
35. Bui CM, Chen H, Shyr Y, Joos KM: Discontinuing nasal steroids might lower intraocular pressure in glaucoma. J Allergy Clin Immunol 2005, 116:1042-1047.
36. Berger W, Abelson MB, Gomes PJ, et al.: Effects of adjuvant therapy with 0.1% olopatadine hydrochloride ophthalmic solution on quality of life in patients with allergic rhinitis using systemic or nasal therapy. Ann Allergy Asthma Immunol 2005, 95:361-371.
37. Bielory L, Lien KW, Bigelsen S: Efficacy and tolerability of newer antihistamines in the treatment of allergic conjunctivitis. Drugs 2005, 65:215-228.
38. Bielory L, Ghafoor S: Histamine receptors and the conjunctiva. Curr Opin Allergy Clin Immunol 2005, 5:437-440.
39. Thorig L, Halperin M, van Haeringen NJ: The fine-thread method: lacrimation test for measuring ocular side-effects of drugs in the rat. Doc Ophthalmol 1983, 56:35-39.
40. Thorig L, Halperin M, van Haeringen NJ: Cotton-thread tear test: an experimental study for testing drugs suspected of side effects on lacrimation. Doc Ophthalmol 1984, 58:307-315.
41. Horak F, Jager S, Berger U: Onset and duration of the effects of three antihistamines in current use - astemizole, loratadine and terfenadine forte - studied during prolonged, controlled allergen challenges in volunteers. J Int Med Res 1992, 20:422-434.
42. Welch D, Ousler GW 3rd, Nally LA, et al.: Ocular drying associated with oral antihistamines (loratadine) in the normal population-an evaluation of exaggerated dose effect. Adv Exp Med Biol 2002, 506 (Pt B): 1051-1055.
43. Ousler GW, Wilcox KA, Gupta G, Abelson MB: An evaluation of the ocular drying effects of 2 systemic antihistamines: loratadine and cetirizine hydrochloride. Ann Allergy Asthma Immunol 2004, 93:460-464.
44. Howell G 3rd, West L, Jenkins C, et al.: In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine. BMC Pharmacol 2005, 5:13.
45. Liu H, Farley JM: Effects of first and second generation antihistamines on muscarinic induced mucus gland cell ion transport. BMC Pharmacol 2005, 5:8.
46. Grumetto L, Cennamo G, Del Prete A, et al.: Pharmacokinetics of cetirizine in tear fluid after a single oral dose. Clin Pharmacokinet 2002, 41:525-531.
47. Tinkelman DG, Reed CE, Nelson HS, Offord KP: Aerosol beclomethasone dipropionate compared with theophylline as primary treatment of chronic, mild to moderately severe asthma in children. Pediatrics 1993, 92:64-77.
48. Volovitz B, Amir J, Malik H, et al.: Growth and pituitary-adrenal function in children with severe asthma treated with inhaled budesonide. N Engl J Med 1993, 329:1703-1708.
49. Ozturk F, Yuceturk AV, Kurt E, et al.: Evaluation of intraocular pressure and cataract formation following the long-term use of nasal corticosteroids. Ear Nose Throat J 1998, 77:846-848, 850-841.
50. Cumming RG, Mitchell P: Inhaled corticosteroids and cataract: prevalence, prevention and management. Drug Saf 1999, 20:77-84.
51. Wagener JS, Wojtczak HA: Inhaled steroids in children: risks versus rewards. J Pediatr 1998, 132(3 Pt 1):381-383.