Glycosylation patterns of human chorionic gonadotropin revealed by liquid chromatography-mass spectrometry and bioinformatics

Electrophoresis

Volumn 27, Issue 13, 2006, Pages 2734-2746

  Toll, Hansjörg ^a   Berger, Peter ^b   Hofmann, Andreas ^a   Hildebrandt, Andreas ^a   Oberacher, Herbert ^a,c   Lenhof, Hans Peter ^a   Huber, Christian G ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Electrospray ionization mass spectrometry; Glycosylation; Heterogeneity; High performance liquid chromatography; Human chorionic gonadotropin

Indexed keywords

AMINO ACIDS; BIOINFORMATICS; ELECTROSPRAY IONIZATION; GLYCOSYLATION; MASS SPECTROMETERS; MASS SPECTROMETRY; MOLECULAR MASS; PEPTIDES; POLYSACCHARIDES; SEARCH ENGINES;

ELECTROSPRAY IONIZATION MASS SPECTROMETRY; GLYCANS; GLYCOFORMS; GLYCOSYLATIONS; HETEROGENEITY; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN CHORIONIC GONADOTROPHINS; INTACT PROTEINS; MASS SPECTRA; POST-TRANSLATIONAL MODIFICATIONS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN ALPHA SUBUNIT; CHORIONIC GONADOTROPIN BETA SUBUNIT; GLYCAN; GLYCOPROTEIN;

ALGORITHM; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ARTICLE; BIOINFORMATICS; COMPUTER PROGRAM; DIAGNOSTIC TEST; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE URINE LEVEL; HUMAN; IMMUNOASSAY; MOLECULAR WEIGHT; OXIDATION; PREGNANCY; PROTEIN ANALYSIS; PROTEIN DATABASE; PROTEIN DENATURATION; PROTEIN DETERMINATION; PROTEIN GLYCOSYLATION; PROTEIN POLYMORPHISM; PROTEIN PROCESSING; PROTEOMICS; REFERENCE VALUE; SEPARATION TECHNIQUE; URINALYSIS;

EID: 33745961481     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200600022     Document Type: Article

References (41)

1. O'Connor, J. F., Birken, S., Lustbader, J. W., Krichevsky, A. et al., Endocrinol. Rev. 1994, 15, 650-683.
2. Cole, L. A., Shahabi, S., Butler, S. A., Mitchell, H. et al., Clin. Chem. 2001, 47, 308-315.
3. Goverman, J. M., Parsons, T. F., Pierce, J. G., J. Biol. Chem. 1982, 257, 15059-15064.
4. Nemansky, M., Thotakura, N. R., Lyons, C. D., Ye, S. et al., J. Biol. Chem. 1998, 273, 12068-12076.
5. Skarulis, M. C., Wehmann, R. E., Nisula, B. C., Blithe, D. L., J. Clin. Endocrinol. Metab. 1992, 75, 91-96.
6. Mizuochi, T., Nishimura, R., Derappe, C., Taniguchi, T. et al., J. Biol. Chem. 1983, 258, 14 126-14 129.
7. Elliott, M. M., Kardana, A., Lustbader, J. W., Cole, L. A., Endocrine 1997, 7, 15-32.
8. Bogart, M. H., Pandian, M. R., Jones, O. W., Prenat Diagn. 1987, 7, 623-630.
9. Berger, P., Sturgeon, C., Bidart, J. M., Paus, E. et at, Tumour Biol. 2002, 23, 1-38.
10. An, H. J., Peavy, T. R., Hedrick, J. L., Lebrilla, C. B., Anal. Chem. 2003, 75, 5628-5637.
11. Demelbauer, U. M., Plematl, A., Josic, D., Allmaier, G., Rizzi, A., J. Chromatogr. A 2005, 1080, 15-21.
12. Demelbauer, U. M., Zehl, M., Plematl, A., Allmaier, G., Rizzi, A., Rapid Commun. Mass Spectrom. 2004, 18, 1575-1582.
13. Wuhrer, M., Deelder, A. M., Hokke, C. H., J. Chromatogr. B 2005, 825, 124-133.
14. Liu, C., Bowers, L. D., J. Mass Spectrom. 1997, 32, 33-42.
15. Kessler, M. J., Reddy, M. S., Shah, R. H., Bahl, O. P., J. Biol. Chem. 1979, 254, 7901-7908.
16. Kessler, M. J., Mise, T., Ghai, R. D., Bahl, O. P., J. Biol. Chem. 1979, 254, 7909-7914.
17. Harvey, D. J., Proteomics 2001, 1, 311-328.
18. Mechref, Y., Muzikar, J., Novotny, M. V., Electrophoresis 2005, 26, 2034-2046.
19. Cancilla, M. T., Penn, S. G., Lebrilla, C. B., Anal. Chem. 1998, 70, 663-672.
20. Cancilla, M. T., Wong, A. W., Voss, L. R., Lebrilla, C. B., Anal. Chem. 1999, 71, 3206-3218.
21. Mechref, Y., Zidek, L., Ma, W., Novotny, M. V., Glycobiology 2000, 10, 231-235.
22. Que, A. H., Novotny, M. V., Anal. Chem. 2002, 74, 5184-5191.
23. Gervais, A., Hammel, Y. A., Pelloux, S., Lepage, P. et al., Glycobiology 2003, 13, 179-189.
24. Fenn, J. B., Mann, M., Meng, C. K., Wong, S. F., Whitehouse, C. M., Science 1989, 246, 64-71.
25. Zolla, L., Rinalducci, S., Timperio, A. M., Huber, C. G., Righetti, P. G., Electrophoresis 2004, 25, 1353-1366.
26. Demelbauer, U. M., Plematl, A., Kremser, L., Allmaier, G. et al., Electrophoresis 2004, 25, 2026-2032.
27. Neusüss, C., Demelbauer, U., Pelzing, M., Electrophoresis 2005, 26, 1442-1450.
28. Liu, C., Bowers, L. D., Clin. Chem. 1997, 43, 1172-1181.
29. Birken, S., Berger, P., Bidart, J. M., Weber, M. et al., Clin. Chem. 2003, 49, 144-154.
30. Premstaller, A., Oberacher, H., Huber, C. G., Anal. Chem. 2000, 72, 4386-4393.
31. Oberacher, H., Walcher, W., Huber, C. G., J. Mass Spectrom. 2003, 38, 108-116.
32. Reinert, K., Kohlbacher, O., Hildebrandt, A., http://open-ms.sourceforge.net.
33. Mise, T., Bahl, O. P., J. Biol. Chem. 1980, 255, 8516-8522.
34. Fujiki, Y., Rathnam, P., Saxena, B. B., Biochim. Biophys. Acta 1980, 624, 428-435.
35. Blithe, D. L., Iles, R. K., Endocrinology 1995, 136, 903-910.
36. Mise, T., Bahl, O. P., J. Biol. Chem. 1981, 256, 6587-6592.
37. Pierce, J. G., Parsons, T. F., Annu. Rev. Biochem. 1981, 50, 465-495.
38. Davis, M. T., Beierle, J., Bures, E. T., McGinley, M. D. et al., J. Chromatogr. B 2001, 752, 281-291.
39. Wang, H., Segal, S. J., Koide, S. S., Endocrinology 1988, 123, 795-803.
40. Laidler, P., Cowan, D. A., Hider, R. C., Keane, A., Kicman, A. T., Rapid Commun. Mass Spectrom. 1995, 9, 1021-1026.
41. Cormen, T. H., Leiserson, C. E., Rivest, R. L., Stein, C., Introduction to Algorithms, MIT Press, Cambridge 2001.