GABA transporters regulate a standing GABAC receptor-mediated current at a retinal presynaptic terminal

Journal of Neuroscience

Volumn 26, Issue 26, 2006, Pages 6979-6984

  Hull, Court ^a   Li, Geng Lin ^a   Von Gersdorff, Henrique ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Bipolar cell; Gaba transporters; GAT 1; Presynaptic excitability; Retina; Tonic inhibition

Indexed keywords

1 [2 (BENZHYDRYLIDENEAMINOOXY)ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID C RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; AMINO ACID TRANSPORTER; PROTEIN GAT1; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID CARRIER; CALCIUM; GABA-C RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE DEPOLARIZATION; FEEDBACK SYSTEM; GABAERGIC SYSTEM; NERVE CONDUCTION; NERVE ENDING; NERVE EXCITABILITY; NERVE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RETINA AMACRINE CELL; RETINA BIPOLAR GANGLION CELL; RETINA NERVE CELL; SIGNAL TRANSDUCTION; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION; SYNAPTOSOME; VOLTAGE CLAMP; ACTION POTENTIAL; ANIMAL; DRUG ANTAGONISM; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGY; GOLDFISH; IN VITRO STUDY; PHYSIOLOGY; RETINA;

ACTION POTENTIALS; ANIMALS; CALCIUM; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGY; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GOLDFISH; PRESYNAPTIC TERMINALS; RECEPTORS, GABA; RETINA; RETINAL BIPOLAR CELLS;

EID: 33745943281     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1386-06.2006     Document Type: Article

References (36)

1. Amin J, Weiss DS (1994) Homomeric rho 1 GABA channels: activation properties and domains. Receptors Channels 2:227-236.
2. Beckman ML, Bernstein EM, Quick MW (1999) Multiple G protein-coupled receptors initiate protein kinase C redistribution of GABA transporters in hippocampal neurons. J Neurosci 19:RC9(1-6).
3. Bernstein EM, Quick MW (1999) Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA. J Biol Chem 274:889-895.
4. Bieda MC, Copenhagen DR (2000) Inhibition is not required for the production of transient spiking responses from retinal ganglion cells. Vis Neurosci 17:243-254.
5. Billups D, Attwell D (2002) Control of intracellular chloride concentration and GABA response polarity in rat retinal ON bipolar cells. J Physiol (Lond) 545:183-198.
6. Deken SL, Wang D, Quick MW (2003) Plasma membrane GABA transporters reside on distinct vesicles and undergo rapid regulated recycling. J Neurosci 23:1563-1568.
7. C feedback at bipolar terminals in tiger salamander retina. J Neurophysiol 79:2171-2180.
8. C-like receptors on catfish cone- but not rod-driven horizontal cells. J Neurosci 14:2648-2658.
9. Flores-Herr N, Protti DA, Wässle H (2001) Synaptic currents generating the inhibitory surround of ganglion cells in the mammalian retina. J Neurosci 21:4852-4863.
10. C receptors on carp retinal bipolar cells. NeuroReport 8:1331-1335.
11. C receptor activation. J Neurosci 22:3285-3292.
12. Ishikane H, Gangi M, Honda S, Tachibana M (2005) Synchronized retinal oscillations encode essential information for escape behavior in frogs. Nat Neurosci 8:1087-1095.
13. Johnson J, Chen TK, Rickman DW, Evans C, Brecha NC (1996) Multiple gamma-aminobutyric acid plasma membrane transporters (GAT-1, GAT-2, GAT-3) in the rat retina. J Comp Neurol 375:212-224.
14. Jonas P (1995) Fast application of agonists to isolated membrane patches. In: Single-channel recording, Ed 2 (Sakmann B, Neher E, eds), pp 231-243. New York: Plenum.
15. Jones MV, Jonas P, Sahara Y, Westbrook G (2001) Microscopic kinetics and energetics distinguish GABA(A) receptor agonists from antagonists. Biophys J 81:26602670.
16. C receptor antagonists on the b-wave of ERG recorded from the isolated rat retina. Vision Res 40:1653-1665.
17. A conductances in rat neocortex. J Neurophysiol 94:2073-2085.
18. Klooster J, Nunes Cardozo B, Yazulla S, Kamermans M (2004) Postsynaptic localization of gamma-aminobutyric acid transporters and receptors in the outer plexiform layer of the goldfish retina: An ultrastructural study. J Comp Neurol 474:58-74.
19. C receptor rho-subunits in the rat retina. Eur J Neurosci 10:115-127.
20. Law RM, Stafford A, Quick MW (2000) Functional regulation of gamma-aminobutyric acid transporters by direct tyrosine phosphorylation. J Biol Chem 275:23986-23991.
21. C receptor-mediated feedback in the mouse inner retina. J Neurophysiol 86:2285-2298.
22. Matthews G, Ayoub GS, Heidelberger R (1994) Presynaptic inhibition by GABA is mediated via two distinct GABA receptors with novel pharmacology. J Neurosci 14:1079-1090.
23. C receptor expression and alters visual processing in the mouse retina. J Neurosci 22:4163-4174.
24. Nusser Z, Mody I (2002) Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells. J Neurophysiol 87:2624-2628.
25. Overstreet LS, Westbrook GL (2003) Synapse density regulates independence at unitary inhibitory synapses. J Neurosci 23:2618-2626.
26. A receptors. J Neurosci 20:7914-7921.
27. 2+ action potentials by exocytosis in goldfish bipolar cell terminals. J Physiol (Lond) 572:747-762.
28. Palmer MJ, Tachenberger H, Hull C, Tremere L, von Gersdorff H (2003) Synaptic activation of presynaptic glutamate transporter currents in nerve terminals. J Neurosci 23:4831-4841.
29. Protti DA, Flores-Herr N, von Gersdorff H (2000) Light evokes calcium spikes in the axon terminals of a retinal bipolar cell. Neuron 25:215-227.
30. Sagdullaev BT, McCall MA, Lukasiewicz PD (2006) Presynaptic inhibition modulates spillover, creating distinct dynamic response ranges of sensory output. Neuron 50:923-935.
31. A receptors: modulating gain and maintaining the tone. Trends Neurosci 27:262-269.
32. Vigh J, Li GL, Hull C, von Gersdorff H (2005) Long-term plasticity mediated by mGluR1 at a retinal reciprocal synapse. Neuron 46:469-482.
33. Yang CY (1998) Gamma-aminobutyric acid transporter-mediated current from bipolar cells in tiger salamander retinal slices. Vision Res 38:2521-2526.
34. Yang CY, Brecha NC, Tsao E (1997) Immunocytochemical localization of GABA plasma membrane transporters in the tiger salamander retina. J Comp Neurol 389:117-126.
35. Zenisek D, Matthews G (1998) Calcium action potentials in retinal bipolar neurons. Vis Neurosci 15:69-75.
36. Zhang J, Jung CS, Slaughter MM (1997) Serial inhibitory synapses in retina. Vis Neurosci 14:553-563.