A CD-MEKC method utilizing a neutral surfactant for enantiomeric purity determination of an oxazolidinone drug candidate

Chromatographia

Volumn 64, Issue 1-2, 2006, Pages 57-64

  Antczak, A ^a   Ramstad, T ^b   Johnson, R ^c  

^a KALAMAZOO COLLEGE   (United States)

^b PFIZER INC   (United States)

^c Pharmaceutical Product Development   (United States)

Author keywords

Brij 35 surfactant; CE method validation; Chiral capillary electrophoresis; Highly sulfated gamma cyclodextrin; Micellar electrokinetic chromatography

Indexed keywords

1 [4 [5 [[(2,2 DIFLUORO 1 THIOETHYL)AMINO]METHYL] 2 OXO 3 OXAZOLIDINYL] 2 FLUOROPHENYL] 4 (HYDROXYACETYL)PIPERAZINE; BUFFER; CYCLODEXTRIN; ELECTROLYTE; LITHIUM DERIVATIVE; OXAZOLIDINONE DERIVATIVE; PHA 549184; POLIDOCANOL; SURFACTANT; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CHIRAL CHROMATOGRAPHY; DRUG DETERMINATION; DRUG SOLUBILITY; ENANTIOMER; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SAMPLE; SENSITIVITY ANALYSIS; STANDARD; VALIDATION PROCESS;

EID: 33745939910     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1365/s10337-006-0828-4     Document Type: Article

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