Cyclodextrin-mediated micellar electrokinetic chromatography and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for the enantiomer separation of racemorphan in human urine

Journal of Chromatography A

Volumn 853, Issue 1-2, 1999, Pages 439-447

  Ban, Eunmi ^a   Choi, Soonwook ^a   Lee, Jeong Ae ^a   Lho, Dong Seok ^a   Yoo, Young Sook ^a  

^a Korea Institute of Science and Technology   (South Korea)

Author keywords

Doping analysis; Enantiomer separation; Racemorphan

Indexed keywords

BETA CYCLODEXTRIN; BUFFER; CYCLODEXTRIN; DEXTROMETHORPHAN; DEXTRORPHAN; DODECYL SULFATE SODIUM; DRUG METABOLITE; LEVORPHANOL; PROPANOL; RACEMORPHAN;

ANALYTIC METHOD; CHIRAL CHROMATOGRAPHY; CONFERENCE PAPER; CONTROLLED STUDY; DESORPTION; DOPING; DRUG URINE LEVEL; ENANTIOMER; HUMAN; HUMAN EXPERIMENT; IONIZATION; LASER; MASS SPECTROMETRY; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PH; PRIORITY JOURNAL; REPRODUCIBILITY; SOLID PHASE EXTRACTION; ULTRAVIOLET SPECTROPHOTOMETRY; VOLUNTEER;

CHROMATOGRAPHY, MICELLAR ELECTROKINETIC CAPILLARY; HUMANS; HYDROGEN-ION CONCENTRATION; LEVORPHANOL; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STEREOISOMERISM;

EID: 0032805541     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(99)00551-8     Document Type: Conference Paper

References (20)

1. Aumatell A., Well R.J. J. Chromatogr. Sci. 31:1993;502.
2. Calensnik B., Chistensen J.A. Clin. Phamacol. Ther. 8:1967;374.
3. Zysset T., Zeugin T., Kupfer A. Biochem. Phamacol. 37:1988;3155.
4. Ward T.J. Anal. Chem. 66:1994;633A.
5. Maris F.A., Vervoort R.J.M., Hindriks H. J. Chromatogr. 547:1991;45.
6. Venema A., Henderiks H. J. High Resolut. Chromatogr. 14:1991;676.
7. Wren S.A.C., Rowe R.C. J. Chromatogr. 603:1992;235.
8. Weiberger R. Practical Capillary Electrophoresis. 1993;Academic Press, New York. Ch. 7.
9. Landes J.P. Handbook of Capillary Electrophoresis. 2nd ed :1997;CRC Press, Boca Raton, FL. Ch. 3.
10. Li S., Fried K., Wainer I.W., Lloyd D.K. Chromatographia. 35:1993;216.
11. Yoo Y.S., Han Y.S., Suh M.J., Park J.S. J. Chromatogr. A. 763:1997;285.
12. Suh M.J., Kim Y.S., Yoo Y.S. J. Chromatogr. A. 781:1997;263.
13. Terabe S., Miyashita Y., Shibata O., Barhart E.R., Alexander L.R., Patterson D.J., Karger B.L., Hosoya K., Tanaka N. J. Chromatogr. 516:1990;23.
14. Nishi H., Fukuyama T., Terabe S. J. Chromatogr. 553:1991;503.
15. Noroski J.E., Mayo D.J., Moran M. J. Pharm. Biomed. Anal. 13:1995;45.
16. Wren S.A.C., Rowe R.C. J. Chromatogr. 609:1992;363.
17. Nishi H., Terabe S. J. Chromatogr. A. 694:1995;245.
18. Bender M.L., Komyama M. Cyclodextrin Chemistry. 1978;Springer, Berlin.
19. Terabe S., Ishihama Y., Nishi H., Fukuyama F., Otska K. J. Chromatogr. 545:1991;359.
20. Wenk M., Keller B., Fellath F. J. Pharm. Biomed. Anal. 9:1991;341.