Finite element simulation of drug release from swelling matrix

International Journal of Nonlinear Sciences and Numerical Simulation

Volumn 7, Issue 3, 2006, Pages 309-312

  Wu, H A ^a   Lei, Z F ^a   Wang, X X ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Arbitrary Lagrangian Eulerian formulation; Drug release; Finite element method; Swelling

Indexed keywords

EID: 33745933484     PISSN: 15651339     EISSN: None     Source Type: Journal    
DOI: 10.1515/IJNSNS.2006.7.3.309     Document Type: Article

References (11)

1. Colombo, P., R. Bettini, and N.A. Peppas, Observation of swelling process and diffusion front position during swelling in hydroxypropyl methyl cellulose (HPMC) matrices containing a soluble drug. Journal of Controlled Release, 1999. 61(1-2): p. 83-91.
2. Siepmann, J., et al., HPMC-matrices for controlled drug delivery: A new model combining diffusion, swelling, and dissolution mechanisms and predicting the release kinetics. Pharmaceutical Research, 1999. 16(11): p. 1748-1756.
3. Kiil, S. and K. Dam-Johansen, Controlled drug delivery from swellable hydroxypropylmethylcellulose matrices: model-based analysis of observed radial front movements. Journal of Controlled Release, 2003. 90(1): p. 1-21.
4. Siepmann, J. and N.A. Peppas, Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Advanced Drug Delivery Reviews, 2001. 48(2-3): p. 139-157.
5. Boobis, A., et al., In silica prediction of ADME and pharmacokinetics - Report of an expert meeting organised by COST B15. European Journal of Pharmaceutical Sciences, 2002. 17(4-5): p. 183-193.
6. Rowland, M., L. Balant, and C. Peck, Physiologically Based Pharmacokinetics in Drug Development and Regula-tory Science: A Workshop Report. AAPS Pharmaceutical Science, 2004. 6(1): p. 1-12.
7. Bathe, K.J., Finite Element Procedures. 1996, New Jersey: Prentice Hall Inc.
8. Gu, B.H., H.P. Zhang, Ballistic impact damage of laminated composite penetrated by cylindrical rigid projectile: A finite element simulation, International Journal of Nonlinear Sciences and Numerical Simulation, 2005, 6 (3): 215-222
9. Kim, Y.H., K.Kim, H.S. Kim, Effects of moment arms on spinal stability subjected to follower loads: A finite element analysis study, International Journal of Nonlinear Sciences and Numerical Simulation, 2005, 6 (3): 311-3162005
10. Zeng, Y.C., H.F. Guo, C.W. Yu,A novel approach to fiber/air flow, International Journal of Nonlinear Sciences and Numerical Simulation, 2005, 6 (3): 329-330
11. Xie, K., G. Song, A. Hou, Y. Liu, Mathematical Model of Reaction for Reactive Dyes Containing Fluorotriazine, Journal of Nonlinear Sciences and Numerical Simulation, 2006, 7(1): 117-118