-
1
-
-
0026320114
-
Incidence and risk factors for gout in white men
-
Roubenoff R, Klag MJ, Mead LA, Liang KY, Seidler AJ, Hochberg MC. Incidence and risk factors for gout in white men. JAMA. 1991;266:3004-3007.
-
(1991)
JAMA
, vol.266
, pp. 3004-3007
-
-
Roubenoff, R.1
Klag, M.J.2
Mead, L.A.3
Liang, K.Y.4
Seidler, A.J.5
Hochberg, M.C.6
-
2
-
-
0001427965
-
Gout and hyperuricemia
-
Ruddy S, Harris ED Jr, Sledge CB, eds. Philadelphia: W. B. Saunders
-
Wortmami RL, Kelley WN. Gout and hyperuricemia. In: Ruddy S, Harris ED Jr, Sledge CB, eds. Kelley's Textbook of Rheumatology. 6th ed. Philadelphia: W. B. Saunders; 2001:1339-1376.
-
(2001)
Kelley's Textbook of Rheumatology. 6th Ed.
, pp. 1339-1376
-
-
Wortmami, R.L.1
Kelley, W.N.2
-
3
-
-
0023634573
-
Asymptomatic hyperuricemia: Risks and consequences in the Normative Aging Study
-
Campion EW, Glynn RJ, DeLabry LO. Asymptomatic hyperuricemia: risks and consequences in the Normative Aging Study. Am J Med. 1987;82:421-426.
-
(1987)
Am J Med
, vol.82
, pp. 421-426
-
-
Campion, E.W.1
Glynn, R.J.2
DeLabry, L.O.3
-
4
-
-
0036286849
-
The association between gout and nephrolithiasis: The National Health and Nutrition Examination Survey III, 1988-1994
-
Kramer HM, Curhan G. The association between gout and nephrolithiasis: the National Health and Nutrition Examination Survey III, 1988-1994. Am J Kidney Dis. 2002;40:37-42.
-
(2002)
Am J Kidney Dis
, vol.40
, pp. 37-42
-
-
Kramer, H.M.1
Curhan, G.2
-
5
-
-
3442899325
-
Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population
-
Wallace KL, Riedel AA, Joseph-Ridge N, Wortmann R. Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population. J Rheumatol. 2004;31:1582-1587.
-
(2004)
J Rheumatol
, vol.31
, pp. 1582-1587
-
-
Wallace, K.L.1
Riedel, A.A.2
Joseph-Ridge, N.3
Wortmann, R.4
-
6
-
-
0027516964
-
Prevention and management of gout
-
Star VL, Hochberg MC. Prevention and management of gout. Drugs. 1993;45:212-222.
-
(1993)
Drugs
, vol.45
, pp. 212-222
-
-
Star, V.L.1
Hochberg, M.C.2
-
7
-
-
0037449776
-
An extremely potent inhibitor of xanthine oxidoreductase: Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition
-
Okamoto K, Eger BT, Nishino T, Kondo S, Pai EF, Nishino T. An extremely potent inhibitor of xanthine oxidoreductase: crystal structure of the enzyme-inhibitor complex and mechanism of inhibition. J Biol Chem. 2003;278:1848-1855.
-
(2003)
J Biol Chem
, vol.278
, pp. 1848-1855
-
-
Okamoto, K.1
Eger, B.T.2
Nishino, T.3
Kondo, S.4
Pai, E.F.5
Nishino, T.6
-
8
-
-
13444257733
-
Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase
-
Takano Y, Hase-Aoki K, Horiuchi H, et al. Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase. Life Sci. 2005;76:1835-1847.
-
(2005)
Life Sci
, vol.76
, pp. 1835-1847
-
-
Takano, Y.1
Hase-Aoki, K.2
Horiuchi, H.3
-
9
-
-
0027205542
-
Hypouricemic effect of the novel xanthine oxidase inhibitor, TEI-6720, in rodents
-
Osada Y, Tsuchimoto M, Fukushima H, et al. Hypouricemic effect of the novel xanthine oxidase inhibitor, TEI-6720, in rodents. Eur J Pharmacol. 1993;241:183-188.
-
(1993)
Eur J Pharmacol
, vol.241
, pp. 183-188
-
-
Osada, Y.1
Tsuchimoto, M.2
Fukushima, H.3
-
10
-
-
0027745255
-
Hypouricemic effect of allopurinol and the novel xanthine oxidase inhibitor TEI-6720 in chimpanzees
-
Komoriya K, Osada Y, Hasegawa M, et al. Hypouricemic effect of allopurinol and the novel xanthine oxidase inhibitor TEI-6720 in chimpanzees. Eur J Pharmacol. 1993;250:455-460.
-
(1993)
Eur J Pharmacol
, vol.250
, pp. 455-460
-
-
Komoriya, K.1
Osada, Y.2
Hasegawa, M.3
-
11
-
-
0033511044
-
A comparative study on the hypouricemic activity and potency in renal xanthine calculus formation of two xanthine oxidase/xanthine dehydrogenase inhibitors: TEI-6720 and allopurinol in rats
-
Horiuchi H, Ota M, Kobayashi M, et al. A comparative study on the hypouricemic activity and potency in renal xanthine calculus formation of two xanthine oxidase/xanthine dehydrogenase inhibitors: TEI-6720 and allopurinol in rats. Res Commun Mol Pathol Pharmacol. 1999;104:307-319.
-
(1999)
Res Commun Mol Pathol Pharmacol
, vol.104
, pp. 307-319
-
-
Horiuchi, H.1
Ota, M.2
Kobayashi, M.3
-
12
-
-
14944345365
-
Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: A twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout
-
Becker MA, Schumacher HR, Wortmann RL, et al. Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout. Arthritis Rheum. 2005;52:916-923.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 916-923
-
-
Becker, M.A.1
Schumacher, H.R.2
Wortmann, R.L.3
-
13
-
-
22744448920
-
Febuxostat, a novel non-purine selective inhibitor of xanthine oxidase, in a phase III placebo-controlled double-blind clinical trial in Japanese subjects with gout or hyperuricemia
-
Kamatani N, Fujimori S, Hada T, et al. Febuxostat, a novel non-purine selective inhibitor of xanthine oxidase, in a phase III placebo-controlled double-blind clinical trial in Japanese subjects with gout or hyperuricemia [abstract]. Arthritis Rheum. 2004;50:S337.
-
(2004)
Arthritis Rheum
, vol.50
-
-
Kamatani, N.1
Fujimori, S.2
Hada, T.3
-
14
-
-
10344260696
-
Febuxostat (TMX-67), a novel, non-purine, selective inhibitor of xanthine oxidase, is safe and decreases serum urate in healthy volunteers
-
Becker MA, Kisicki J, Khosravan R, et al. Febuxostat (TMX-67), a novel, non-purine, selective inhibitor of xanthine oxidase, is safe and decreases serum urate in healthy volunteers. Nucleosides Nucleotides Nucleic Acid. 2004;23:1111-1116.
-
(2004)
Nucleosides Nucleotides Nucleic Acid
, vol.23
, pp. 1111-1116
-
-
Becker, M.A.1
Kisicki, J.2
Khosravan, R.3
-
15
-
-
28944437578
-
Febuxostat compared with allopurinol in patients with hyperuricemia and gout
-
Becker MA, Schumacher HR, Wortmann RL, et al. Febuxostat compared with allopurinol in patients with hyperuricemia and gout. N Engl J Med. 2005;353:2450-2461.
-
(2005)
N Engl J Med
, vol.353
, pp. 2450-2461
-
-
Becker, M.A.1
Schumacher, H.R.2
Wortmann, R.L.3
-
16
-
-
29644432854
-
Metabolic fate of [14C]-TEI-6720, a novel xanthine oxidase inhibitor: Tissue distribution after oral administration in rats, protein binding and metabolism in vivo and in vitro
-
Kondo S, Nishimura S, Mochizuki T, et al. Metabolic fate of [14C]-TEI-6720, a novel xanthine oxidase inhibitor: tissue distribution after oral administration in rats, protein binding and metabolism in vivo and in vitro [abstract]. Drug Metab Review. 1995;18:56.
-
(1995)
Drug Metab Review
, vol.18
, pp. 56
-
-
Kondo, S.1
Nishimura, S.2
Mochizuki, T.3
-
17
-
-
22744459654
-
Metabolites of TMX-67, a new pharmaceutical entity for the treatment of gout or hyperuricemia, and their pharmacokinetic profiles in human
-
Hoshide S, Nishimura S, Ishii S, Matsuzawa K, Saito N, Tanaka T. Metabolites of TMX-67, a new pharmaceutical entity for the treatment of gout or hyperuricemia, and their pharmacokinetic profiles in human [abstract]. Drug Metab Rev. 2000;32:269.
-
(2000)
Drug Metab Rev
, vol.32
, pp. 269
-
-
Hoshide, S.1
Nishimura, S.2
Ishii, S.3
Matsuzawa, K.4
Saito, N.5
Tanaka, T.6
-
18
-
-
17144396355
-
Pharmacokinetics and pharmacodynamics of febuxostat, a new non-purine selective inhibitor of xanthine oxidase in subjects with renal impairment
-
Mayer MD, Khosravan R, Vernillet L, Wu J, Joseph-Ridge N, Mulford DJ. Pharmacokinetics and pharmacodynamics of febuxostat, a new non-purine selective inhibitor of xanthine oxidase in subjects with renal impairment. Am J Ther. 2005;12:22-34.
-
(2005)
Am J Ther
, vol.12
, pp. 22-34
-
-
Mayer, M.D.1
Khosravan, R.2
Vernillet, L.3
Wu, J.4
Joseph-Ridge, N.5
Mulford, D.J.6
-
19
-
-
0017210803
-
Kinetics of indomethacin absorption, elimination and enterohepatic circulation in man
-
Kwan KC, Breault GO, Umbenhauer ER, McMahon FG, Duggan DE. Kinetics of indomethacin absorption, elimination and enterohepatic circulation in man. J Pharmacokinet Biopharm. 1975;4:255-280.
-
(1975)
J Pharmacokinet Biopharm
, vol.4
, pp. 255-280
-
-
Kwan, K.C.1
Breault, G.O.2
Umbenhauer, E.R.3
McMahon, F.G.4
Duggan, D.E.5
-
20
-
-
0018131361
-
Studies on the fate of naproxen II: Metabolic fate in various animals and man
-
Sugawara Y, Fujihara M, Miura K, Hayashida K, Takahashi T. Studies on the fate of naproxen II: metabolic fate in various animals and man. Chem Pharm Bull. 1978;26:3312-3321.
-
(1978)
Chem Pharm Bull
, vol.26
, pp. 3312-3321
-
-
Sugawara, Y.1
Fujihara, M.2
Miura, K.3
Hayashida, K.4
Takahashi, T.5
-
21
-
-
0016201597
-
Protein binding of indomethacin: Binding of indomethacin to human plasma albumin and its displacement from binding by ibuprofen, phenylbutazone and salicylate, in vitro
-
Mason RW, MacQueen EG. Protein binding of indomethacin: binding of indomethacin to human plasma albumin and its displacement from binding by ibuprofen, phenylbutazone and salicylate, in vitro. Pharmacol. 1974;12:12-19.
-
(1974)
Pharmacol
, vol.12
, pp. 12-19
-
-
Mason, R.W.1
MacQueen, E.G.2
-
22
-
-
8244257840
-
The plasma protein binding properties of a new non-steroidal anti-inflammatory agent
-
Ellis DJ, Martin B. The plasma protein binding properties of a new non-steroidal anti-inflammatory agent [abstract]. Fed Proc. 1971;30:1200.
-
(1971)
Fed Proc
, vol.30
, pp. 1200
-
-
Ellis, D.J.1
Martin, B.2
-
23
-
-
0019785115
-
Clinical pharmacokinetics of indomethacin
-
Helleberg L. Clinical pharmacokinetics of indomethacin. Clin Pharmacokinet. 1981;6:245-258.
-
(1981)
Clin Pharmacokinet
, vol.6
, pp. 245-258
-
-
Helleberg, L.1
-
25
-
-
0017860713
-
The interaction between indomethacin and probenecid
-
Baber N, Holliday L, Sibeon R, Littler T, Orme MLE. The interaction between indomethacin and probenecid. Clin Pharmacol Ther. 1978;24:298-307.
-
(1978)
Clin Pharmacol Ther
, vol.24
, pp. 298-307
-
-
Baber, N.1
Holliday, L.2
Sibeon, R.3
Littler, T.4
Orme, M.L.E.5
-
26
-
-
0018256314
-
Naproxen-probenecid interaction
-
Runkel R, Mroszczak E, Chaplin M, Sevellus H, Segre E. Naproxen-probenecid interaction. Clin Pharmacol Ther. 1978;24:706-713.
-
(1978)
Clin Pharmacol Ther
, vol.24
, pp. 706-713
-
-
Runkel, R.1
Mroszczak, E.2
Chaplin, M.3
Sevellus, H.4
Segre, E.5
-
27
-
-
0025850455
-
The effect of various drugs on the pharmacokinetics of zidovudine (azidothymidine; AZT) by human liver microsomes
-
Sim SM, Back DJ, Breckenridge AM. The effect of various drugs on the pharmacokinetics of zidovudine (azidothymidine; AZT) by human liver microsomes. Br J Clin Pharmacol. 1991;32:17-21.
-
(1991)
Br J Clin Pharmacol
, vol.32
, pp. 17-21
-
-
Sim, S.M.1
Back, D.J.2
Breckenridge, A.M.3
-
28
-
-
0028837971
-
(S)oxazepam glucuronidation is inhibited by ketoprofen and other susbstrates of UGT2B7
-
Patel M, Tang BK, Kalow W. (S)oxazepam glucuronidation is inhibited by ketoprofen and other susbstrates of UGT2B7. Pharmacogenetics. 1995;5:43-49.
-
(1995)
Pharmacogenetics
, vol.5
, pp. 43-49
-
-
Patel, M.1
Tang, B.K.2
Kalow, W.3
-
29
-
-
0027181456
-
The effects of indomethacin and naproxen on zidovudine pharmacokinetics
-
Barry M, Howe J, Back D, et al. The effects of indomethacin and naproxen on zidovudine pharmacokinetics. Br J Clin Pharmacol. 1993;36:82-85.
-
(1993)
Br J Clin Pharmacol
, vol.36
, pp. 82-85
-
-
Barry, M.1
Howe, J.2
Back, D.3
-
31
-
-
1842298228
-
The fate of rectally administered radioactive indomethacin in human subjects: A preliminary report
-
Rothermich NO. The fate of rectally administered radioactive indomethacin in human subjects: a preliminary report. Clin Pharmacol Ther. 1971;12:300-301.
-
(1971)
Clin Pharmacol Ther
, vol.12
, pp. 300-301
-
-
Rothermich, N.O.1
-
32
-
-
0017210803
-
Kinetics of indomethacin absorption, elimination and enterohepatic circulation in man
-
Kwan KC, Breault GO, Umbenhauer ER, McMahon FG, Duggan DE. Kinetics of indomethacin absorption, elimination and enterohepatic circulation in man. J Pharmacokinet Biopharm. 1975;4:255-280.
-
(1975)
J Pharmacokinet Biopharm
, vol.4
, pp. 255-280
-
-
Kwan, K.C.1
Breault, G.O.2
Umbenhauer, E.R.3
McMahon, F.G.4
Duggan, D.E.5
-
33
-
-
22344442057
-
Glucuronidation of nonsteroidal anti-inflammatory drugs: Identifying the enzymes responsible in human liver microsomes
-
Kuehl GE, Lampe JW, Potter JD, Bigler J. Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes. Drug Metab Dispos. 2005;33:1027-1035.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1027-1035
-
-
Kuehl, G.E.1
Lampe, J.W.2
Potter, J.D.3
Bigler, J.4
-
34
-
-
33646537617
-
Febuxostat vs allopurinol and placebo in subjects with hyperuricemia and gout: The 28-week APEX study
-
Schumacher HR, Becker MA, Wortmann RL, et al. Febuxostat vs allopurinol and placebo in subjects with hyperuricemia and gout: the 28-week APEX study [abstract]. Arthritis Rheum. 2005;52:S680.
-
(2005)
Arthritis Rheum
, vol.52
-
-
Schumacher, H.R.1
Becker, M.A.2
Wortmann, R.L.3
-
35
-
-
33745874833
-
Pharmacokinetics of single dose administration of naproxen at 10:00 and 22:00 hours
-
Rao BR, Rambhau D, Rao VVS. Pharmacokinetics of single dose administration of naproxen at 10:00 and 22:00 hours. Chronobiol Int. 1992;9:1436-1441.
-
(1992)
Chronobiol Int
, vol.9
, pp. 1436-1441
-
-
Rao, B.R.1
Rambhau, D.2
Rao, V.V.S.3
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